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of 2
pro vyhledávání: '"Aisling Hall"'
Autor:
Gretchen Pritchard, Aisling Hall, Sagie Wagage, Christopher Dupont, Steven Reiner, Christopher Hunter
Publikováno v:
The Journal of Immunology. 190:134.4-134.4
The role of T-bet, a hallmark transcription factor of Type 1 immune responses, has been examined in a variety of infection models. The results of these studies have been contradictory in that the immune response to some pathogens (e.g. Salmonella, TB
Autor:
Kiyoshi Hirahara, Kamran Ghoreschi, Xiang-Ping Yang, Hayato Takahashi, Arian Laurence, Golnaz Vahedi, Giuseppe Sciumè, Aisling Hall, Christopher Dupont, Loise Francisco, Qian Chen, Masao Tanaka, Yuka Kanno, Hong-Wei Sun, Arlene Sharpe, Christopher Hunter, John O’Shea
Publikováno v:
The Journal of Immunology. 188:59.1-59.1
Interleukin (IL)-27 is a key immunosuppressive cytokine that counters Th17-mediated pathology. To identify mechanisms by which IL-27 might exert its immunosuppressive effect, we analyzed genes in naïve CD4+ T cells rapidly induced by IL-27 stimulat