Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Aisling Chaney"'
1
Akademický článek
Infection Augments Expression of Mechanosensing Piezo1 Channels in Amyloid Plaque-Reactive Astrocytes
Autor: María Velasco-Estevez, Myrthe Mampay, Hervé Boutin, Aisling Chaney, Peter Warn, Andrew Sharp, Ellie Burgess, Emad Moeendarbary, Kumlesh K. Dev, Graham K. Sheridan
Publikováno v: Frontiers in Aging Neuroscience, Vol 10 (2018)
A defining pathophysiological hallmark of Alzheimer’s disease (AD) is the amyloid plaque; an extracellular deposit of aggregated fibrillar Aβ1-42 peptides. Amyloid plaques are hard, brittle structures scattered throughout the hippocampus and cereb
Externí odkaz: https://doaj.org/article/4df186f4fb1d4111b88addf82ee99b77
Zobrazit plný text záznamu
2
Visions by Women in Molecular Imaging Network: Antiracism and Allyship in Action
Autor: Mona Purcell, Carmen Azevedo, Jenny N. Ijoma, Savita Dhanvantari, Patrícia M. R. Pereira, Xiaowei Wang, Oluwatosin Y. Ibhagui, Aisling Chaney, Kyeara N. Mack, Veronica L. Nagle, Oluwatayo F. Ikotun, Vanessa A. Sanders, Eman A. Akam, Monica Shokeen, Kelly E. Henry, Kimberly J. Edwards
Publikováno v: Molecular Imaging and Biology
Recent events in America in 2020 have stimulated a worldwide movement to dismantle anti-Black racism in all facets of our lives. Anti-Black racism is, as defined by the Movement for Black Lives, a "term used to specifically describe the unique discri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac766cbc33eae715471f6f263d66812
https://doi.org/10.1007/s11307-021-01597-x
Zobrazit plný text záznamu
3
Neuroinflammation PET Imaging: Current Opinion and Future Directions
Autor: Mackenzie L. Carlson, Isaac M. Jackson, Michelle L. James, Poorva Jain, Anoushka Rao, Aisling Chaney
Publikováno v: J Nucl Med
Neuroinflammation is a key pathologic hallmark of numerous neurologic diseases, however, its exact role in vivo is yet to be fully understood. PET imaging enables investigation, quantification, and tracking of different neuroinflammation biomarkers i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f7347f3c56e1fe19e9f668517c6acf
https://doi.org/10.2967/jnumed.119.229443
Zobrazit plný text záznamu
4
11C-DPA-713 Versus 18F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke
Autor: Kendra J. Lechtenberg, Marion S. Buckwalter, Aisling Chaney, Haley C. Cropper, Emily M. Johnson, Todd C. Peterson, Marc Y. Stevens, Michelle L. James
Publikováno v: Journal of Nuclear Medicine
Neuroinflammation plays a key role in neuronal injury after ischemic stroke. PET imaging of translocator protein 18 kDa (TSPO) permits longitudinal, noninvasive visualization of neuroinflammation in both preclinical and clinical settings. Many TSPO t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb7e4106c1d6d590d433009d6ca9dfc
http://europepmc.org/articles/PMC6354224
Zobrazit plný text záznamu
5
Whole-body PET Imaging of T-cell Response to Glioblastoma
Autor: Michelle L. James, Zunyu Xiao, Carmel T. Chan, Sanjiv S. Gambhir, Aaron T. Mayer, Tomomi Nobashi, Aisling Chaney
Publikováno v: Clin Cancer Res
Purpose:Immunotherapy is a promising approach for many oncological malignancies, including glioblastoma, however, there are currently no available tools or biomarkers to accurately assess whole-body immune responses in patients with glioblastoma trea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b84304852f6d858e852f3c29211774
https://pubmed.ncbi.nlm.nih.gov/34548318
Zobrazit plný text záznamu
6
Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer's disease rats
Autor: Graham K. Sheridan, Maria Velasco-Estevez, Kumlesh K. Dev, Aisling Chaney, Hervé Boutin, Myrthe Mampay, Emad Moeendarbary, Sara O. Rolle
Publikováno v: Mampay, M, Velasco-Estevez, M, Rolle, S O, Chaney, A M, Boutin, H, Dev, K K, Moeendarbary, E & Sheridan, G K 2021, ' Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer's disease rats ', FEBS open bio . https://doi.org/10.1002/2211-5463.13036
FEBS Open Bio
Upregulation of the transcription factor, REST, is neuroprotective in the ageing brain. We quantified changes in nuclear REST expression in the brains of ageing wild‐type (WT) and Alzheimer’s disease (AD) rats. REST increased in structures involv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc94e35768f220f05c828ee09bb86177
https://doi.org/10.1002/2211-5463.13036
Zobrazit plný text záznamu
10
Development of a CD19 PET tracer for detecting B cells in a mouse model of multiple sclerosis
Autor: Marion S. Buckwalter, Michelle L. James, Isaac M. Jackson, Kendra J. Lechtenberg, Haley C. Cropper, Katherine L. Lucot, Aisling Chaney, Marc Y. Stevens
Publikováno v: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammation
Background B cells play a central role in multiple sclerosis (MS) through production of injurious antibodies, secretion of pro-inflammatory cytokines, and antigen presentation. The therapeutic success of monoclonal antibodies (mAbs) targeting B cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5c4e0228341946574d70239dca4508
https://doi.org/10.21203/rs.3.rs-19155/v1
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje