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pro vyhledávání: '"Aishwarya S. Iyer"'
Autor:
Aishwarya S. Iyer, Issac Chaudry, Seung H. Choi, Matthew R. Orellana, Tatiana Rodriguez, Bryce Edwards, Hannah Carter, Michael W. Lopresti, Siarhei Kharytonchyk, Karndeep Singh, Lindsay Glang, Kailan Stewart, Jana Hijji, Ubiomo Oboh, Alice Telesnitsky, Joshua D. Brown, David A. Case, Frances Grace Ghinger, Yash Desai, Dillion Francis, Michael F. Summers, Ghazal Becker, Patrick Chen
Publikováno v:
Science
One guanosine determines transcript fate Transcripts of the HIV-1 RNA genome can be either spliced and translated into viral proteins or packaged into new virions as a progeny genome. The path taken depends on whether the transcript contains one guan
Autor:
Joshua D. Brown, Michael F. Summers, Aishwarya S. Iyer, John Collins, Alice Telesnitsky, Siarhei Kharytonchyk, Krista L. Stilger, Saif Yasin
Publikováno v:
Journal of Molecular Biology. 430:2066-2079
The packaging signal (Ψ) and Rev responsive element (RRE), enable unspliced HIV-1 RNAs’ export from the nucleus and packaging into virions. For some retroviruses, engrafting Ψ onto a heterologous RNA is sufficient to direct encapsidation. In cont