Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aishwarya Movva"'
Autor:
Srikanth Neelakantham, Tapan K. Majumdar, Aishwarya Movva, Atish Salunke, Charles D. Meyers, Kenneth Kulmatycki, Anne Crissey, Jin Chen, Adele Noe
Publikováno v:
Clinical Pharmacology in Drug Development. 5:450-459
Pradigastat, a novel diacylglycerol acyltransferase 1 inhibitor, has been studied in familial chylomicronemia syndrome. To evaluate the effects of supratherapeutic concentrations of pradigastat on the QTc interval, 2 studies were conducted. The first
Autor:
Jin Chen, Gangadhar Sunkara, Kenneth Kulmatycki, Sam Rebello, Tapan K. Majumdar, Arpine Vapurcuyan, Aishwarya Movva, Atish Salunke, Dan Meyers, Imad Hanna, Adrienne Natrillo
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 53:345-355
Objective An in vitro drugdrug interaction (DDI) study was performed to assess the potential for pradigastat to inhibit breast cancer resistance protein (BCRP), organic anion-transporting polypeptide (OATP), and organic anion transporter 3 (OAT3) tra