Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aishwarya Bhaskar"'
Autor:
Lyndi M. Rice, Jing-Jing Yang, Mariya Nestor, Aishwarya Bhaskar, Sophie Bail, Amy Werda, Michelle Pusey, Ewa Wandzioch
PDF file - 340K, Table S1. siRNA and shRNA sequences targeting the gene PPME1, which codes for PME-1 protein. Table S2. Tumor and normal adjacent tissue (NAT) matched pairs were purchased from Proteogenex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd51a4ea07cca8d8e067b9a27cacda4
https://doi.org/10.1158/0008-5472.22398746
https://doi.org/10.1158/0008-5472.22398746
Autor:
Christopher L. Carpenter, Eldridge N. Nartey, Dominic Suarez, Elisabeth A. Minthorn, Jesus R. Medina, Louis V. LaFrance, Ralph A. Rivero, James F. Mack, Charles F. McHugh, Xinrong Tian, Dirk A. Heerding, Christina Ng Di Marco, Thomas J. Berrodin, Aishwarya Bhaskar, Biju Mangatt, William Hoi Hong Li, Brackley James, Martyr Cuthbert, Lorena A. Kallal, Michael Butticello, Jacob Rubin
Publikováno v:
Journal of Medicinal Chemistry. 64:16056-16087
Elevated expression of the c-MYC oncogene is one of the most common abnormalities in human cancers. Unfortunately, efforts to identify pharmacological inhibitors that directly target MYC have not yet yielded a drug-like molecule due to the lack of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be3a3a04dfdce0aa0aa268d1655c5476
https://doi.org/10.1021/acs.jmedchem.1c01416
https://doi.org/10.1021/acs.jmedchem.1c01416
Autor:
Gurpreet Kapoor, Stefan Zajic, Sunil Suchindran, Jaegil Kim, Uma Saxena, Aishwarya Bhaskar, Heather Kaczynski, Michael Nathenson, Jimson D'Souza, Benjamin Rich, Sandra D'Angelo, Mihaela Druta, Brian Van Tine, Neeta Somaiah, David Liebner, Scott Schuetze, Ioanna Eleftheriadou
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e345a61468fc594a656a5c54b5a416
https://doi.org/10.1136/jitc-2022-sitc2022.0601
https://doi.org/10.1136/jitc-2022-sitc2022.0601
Autor:
Jesús R, Medina, Xinrong, Tian, William H, Li, Dominic, Suarez, James F, Mack, Louis, LaFrance, Cuthbert, Martyr, James, Brackley, Christina, Di Marco, Ralph, Rivero, Dirk A, Heerding, Charles, McHugh, Elisabeth, Minthorn, Aishwarya, Bhaskar, Jacob, Rubin, Michael, Butticello, Christopher, Carpenter, Eldridge N, Nartey, Thomas J, Berrodin, Lorena A, Kallal, Biju, Mangatt
Publikováno v:
Journal of medicinal chemistry. 64(21)
Elevated expression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30e906e5f811e1b96b38c311683c1ee4
https://pubmed.ncbi.nlm.nih.gov/34669409
https://pubmed.ncbi.nlm.nih.gov/34669409
Autor:
Natalie Barnett-Bernodat, Joseph T. Nickels, Rajash Pallai, Aishwarya Bhaskar, Christina Gallo-Ebert, Lyndi M. Rice, Michelle Pusey
Publikováno v:
Tumor Biology. 36:6383-6390
Using yeast two-hybrid analysis, we identified several novel protein interactions for the oncoprotein Cancerous Inhibitor of PP2A (CIP2A) and confirmed a subset of these interactions in human cancer cell lines. Analysis of the interaction in prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe282de6ea9942ec316c43f34f561f6
https://doi.org/10.1007/s13277-015-3326-1
https://doi.org/10.1007/s13277-015-3326-1
Autor:
Lyndi M. Rice, Aishwarya Bhaskar, Christina Gallo-Ebert, Rajash Pallai, Natalie Barnett-Bernodat, Joseph T. Nickels
Publikováno v:
Tumor Biology. 36:6067-6074
Yeast two-hybrid (Y2H) studies have shown that cancerous Inhibitor of protein phosphatase 2A (CIP2A) interacted with several proteins, including leucine-rich repeat-containing protein 59 (LRRC59), suggesting that CIP2A may interact with the chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035a09c612252c8bfb4ca64d1dfd8919
https://doi.org/10.1007/s13277-015-3284-7
https://doi.org/10.1007/s13277-015-3284-7
Publikováno v:
Transcription. 3:323-335
Cancerous inhibitor of protein phosphatase 2A (CIP2A) has been identified as a proto-oncogene that is overexpressed in various types of human cancers. CIP2A acts by inhibiting protein phosphatase 2A-dependent destabilization of c-Myc, resulting in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae041dfdb1c90ca5a1865ff60809bb5
https://doi.org/10.4161/trns.22518
https://doi.org/10.4161/trns.22518
Autor:
Ewa Wandzioch, Amy Werda, Sophie Bail, Michelle Pusey, Aishwarya Bhaskar, Lyndi M. Rice, Jing-Jing Yang, Mariya Nestor
Publikováno v:
Cancer research. 74(16)
Protein phosphatase 2A (PP2A) negatively regulates tumorigenic signaling pathways, in part, by supporting the function of tumor suppressors like p53. The PP2A methylesterase PME-1 limits the activity of PP2A by demethylating its catalytic subunit. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ed260228cfeee73aec560123fb692f
https://pubmed.ncbi.nlm.nih.gov/24928782
https://pubmed.ncbi.nlm.nih.gov/24928782
Autor:
Walter F. Stafford, Yuri L. Lyubchenko, TuKiet T. Lam, Aishwarya Bhaskar, Roopa Thapar, Patrick Itotia, Ronald Berezney, Nitin Bansal, Minyou Zhang, Andrew Fritz, Eunhee Lee, Lyudmila S. Shlyakhtenko
Publikováno v:
Biochemistry. 52(3)
The SLIP1-SLBP complex activates translation of replication-dependent histone mRNAs. In this report, we describe how the activity of the SLIP1-SLBP complex is modulated by phosphorylation and oligomerization. Biophysical characterization of the free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd45909478b658d35a034c17e98f488
https://pubmed.ncbi.nlm.nih.gov/23286197
https://pubmed.ncbi.nlm.nih.gov/23286197
Autor:
Bansal, Nitin, Minyou Zhang, Aishwarya Bhaskar, Patrick Itotia, EunHee Lee, Shlyakhtenko, Lyudmila S., Lam, TuKiet T., Fritz, Andrew, Berezney, Ronald, Lyubchenko, Yuri L., Stafford, Walter F., Thapar, Roopa
Publikováno v:
Biochemistry; 1/22/2013, Vol. 52 Issue 3, p520-536, 17p