Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aishwarya A. Gogate"'
Autor:
David F. Read, Gregory T. Booth, Riza M. Daza, Dana L. Jackson, Rula Green Gladden, Sanjay R. Srivatsan, Brent Ewing, Jennifer M. Franks, Cailyn H. Spurrell, Anne Roshella Gomes, Diana O’Day, Aishwarya A. Gogate, Beth K. Martin, Haleigh Larson, Christian Pfleger, Lea Starita, Yiing Lin, Jay Shendure, Shin Lin, Cole Trapnell
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Sex differences and age-related changes in the human heart at the tissue, cell, and molecular level have been well-documented and many may be relevant for cardiovascular disease. However, how molecular programs within individual cell types v
Externí odkaz:
https://doaj.org/article/c78d59de759c46328c8bc8b520ab680e
Autor:
Melodi Tastemel, Aishwarya A. Gogate, Venkat S. Malladi, Kim Nguyen, Courtney Mitchell, Laura A. Banaszynski, Xiaoying Bai
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 250-255 (2017)
The pluripotency of embryonic stem cells (ESCs) relies on appropriate responsiveness to developmental cues. Promoter-proximal pausing of RNA polymerase II (Pol II) has been suggested to play a role in keeping genes poised for future activation. To id
Externí odkaz:
https://doaj.org/article/ba75b43b27ef4c13a2bc5597abb2a31f
Autor:
Xiuli Liu, Aishwarya A. Gogate, Melodi Tastemel, Venkat S. Malladi, Huiyu Yao, Kim Nguyen, Lily Jun-Shen Huang, Xiaoying Bai
Publikováno v:
Blood Advances, Vol 1, Iss 18, Pp 1358-1367 (2017)
Abstract: The negative elongation factor (NELF) complex is a metazoan-specific factor essential for establishing transcription pausing. Although NELF has been implicated in cell-fate regulation, the cellular regulation of NELF and its intrinsic role
Externí odkaz:
https://doaj.org/article/5896cb85a68d4dcc99f3ca330bbac786
Autor:
David F Read, Gregory T Booth, Riza M Daza, Dana L Jackson, Rula Green Gladden, Sanjay R Srivatsan, Brent Ewing, Jennifer M Franks, Cailyn H Spurrell, Anne Roshella Gomes, Diana O’Day, Aishwarya A Gogate, Beth K Martin, Lea Starita, Yiing Lin, Jay Shendure, Shin Lin, Cole Trapnell
Sex differences and age-related changes in the human heart at the tissue, cell, and molecular level have been well-documented and many may be relevant for cardiovascular disease. However, how molecular programs within individual cell types vary acros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a5e2ad749e3c77922df18cb42ac3c8
https://doi.org/10.1101/2022.07.12.496461
https://doi.org/10.1101/2022.07.12.496461
Autor:
Kenneth L, Chiou, Alex R, DeCasien, Katherina P, Rees, Camille, Testard, Cailyn H, Spurrell, Aishwarya A, Gogate, Hannah A, Pliner, Sébastien, Tremblay, Arianne, Mercer, Connor J, Whalen, Josué E, Negrón-Del Valle, Mareike C, Janiak, Samuel E, Bauman Surratt, Olga, González, Nicole R, Compo, Michala K, Stock, Angelina V, Ruiz-Lambides, Melween I, Martínez, Melissa A, Wilson, Amanda D, Melin, Susan C, Antón, Christopher S, Walker, Jérôme, Sallet, Jason M, Newbern, Lea M, Starita, Jay, Shendure, James P, Higham, Lauren J N, Brent, Michael J, Montague, Michael L, Platt, Noah, Snyder-Mackler
Publikováno v:
Nat Neurosci
Aging is accompanied by a host of social and biological changes that correlate with behavior, cognitive health and susceptibility to neurodegenerative disease. To understand trajectories of brain aging in a primate, we generated a multiregion bulk (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9838c4f453b08a97ddee61f15c2c2d49
https://pubmed.ncbi.nlm.nih.gov/36424430
https://pubmed.ncbi.nlm.nih.gov/36424430
Human Trophoblast Differentiation Is Associated With Profound Gene Regulatory and Epigenetic Changes
Publikováno v:
Endocrinology
Defective placental implantation and vascularization with accompanying hypoxia contribute to preeclampsia (PE), a leading cause of maternal and neonatal morbidity and mortality. Genetic and epigenetic mechanisms underlying differentiation of prolifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a7aa91ea6835d14059eb0fc7a513e7
https://doi.org/10.1210/en.2019-00144
https://doi.org/10.1210/en.2019-00144
Autor:
Jennifer Nguyen, Yu-Ching Teng, Laura A. Banaszynski, Aishwarya A. Gogate, Sara Martire, Amanuel Tafessu, Amanda Whitmill, Melodi Tastemel
Publikováno v:
Nature genetics
The histone variant H3.3 is enriched at enhancers and active genes, as well as repeat regions such as telomeres and retroelements, in mouse embryonic stem cells (mESCs)1–3. Although recent studies demonstrate a role for H3.3 and its chaperones in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798da4d808f89ce9a32126c031714352
https://doi.org/10.1038/s41588-019-0428-5
https://doi.org/10.1038/s41588-019-0428-5
Autor:
Huiyu Yao, Melodi Tastemel, Xiaoying Bai, Kim Nguyen, Venkat S. Malladi, Xiuli Liu, Lily Jun Shen Huang, Aishwarya A. Gogate
Publikováno v:
Blood Advances. 1:1358-1367
The negative elongation factor (NELF) complex is a metazoan-specific factor essential for establishing transcription pausing. Although NELF has been implicated in cell-fate regulation, the cellular regulation of NELF and its intrinsic role in specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f7d0b3719859f2fb9d6b15a20cc2ed
https://doi.org/10.1182/bloodadvances.2017008383
https://doi.org/10.1182/bloodadvances.2017008383