Výsledky vyhledávání - "Aishika, Datta"

Pharmacological Strategies for Stroke Intervention: Assessment of Pathophysiological Relevance and Clinical Trials

Autor: Geetesh, Verma, Deepaneeta, Sarmah, Aishika, Datta, Avirag, Goswami, Nikita, Rana, Harpreet, Kaur, Anupom, Borah, Sudhir, Shah, Pallab, Bhattacharya

Publikováno v: Clinical Neuropharmacology. 46:17-30

The present review describes stroke pathophysiology in brief and discusses the spectrum of available treatments with different promising interventions that are in clinical settings or are in clinical trials.Relevant articles were searched using Googl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9f5650fc59985ee5d9a6f18e8465ab
https://doi.org/10.1097/wnf.0000000000000534

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Phyllanthus emblica L. Regulates BDNF/PI3K Pathway to Modulate Glutathione for Mitoprotection and Neuroprotection in a Rodent Model of Ischemic Stroke

Autor: Pallab Bhattacharya, Deepaneeta Sarmah, Geetesh Verma, Aishika Datta, Namrata Vadak, Antra Chaudhary, Kiran Kalia

Publikováno v: Central Nervous System Agents in Medicinal Chemistry. 22:175-187

Introduction: Ischemic stroke remains the leading cause of death worldwide and is the primary cause of disability globally. Numerous studies have shown that plant-origin medicines are promising and can influence the treatment of neurological disorder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a0ec6d943719c722f9489f62d9c576c
https://doi.org/10.2174/1871524922666220607093400

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Endovascular Stem Cell Therapy Promotes Neuronal Remodeling to Enhance Post Stroke Recovery by Alleviating Endoplasmic Reticulum Stress Modulated by BDNF Signaling

Autor: Harpreet Kaur, Deepaneeta Sarmah, Aishika Datta, Anupom Borah, Dileep R Yavagal, Pallab Bhattacharya

Publikováno v: Stem Cell Reviews and Reports. 19:264-274

The impact of increased BDNF expression in brain by endovascular delivered mesenchymal stem cells (MSCs) post stroke towards modulating endoplasmic reticulum (ER) stress mediated neuronal remodeling has not been directly studied. Therefore, the prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb5ab6127141c22c107810b1c336dfc
https://doi.org/10.1007/s12015-022-10461-6

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Drug repurposing for stroke intervention

Autor: Debarati, Ghosh, Karan, Sehgal, Babasaheb, Sodnar, Nikhil, Bhosale, Deepaneeta, Sarmah, Aishika, Datta, Antra, Chaudhary, Kiran, Kalia, Xin, Wang, Pallab, Bhattacharya

Publikováno v: Drug Discovery Today. 27:1974-1982

Despite the availability of advanced interventions, stroke remains one of the most significant causes of mortality and morbidity worldwide. US Food and Drug Administration (FDA)-approved treatment options for stroke include tissue plasminogen activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8d9acb73505b8e35a410da826961b1
https://doi.org/10.1016/j.drudis.2022.03.003

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Advancement in CRISPR/Cas9 Technology to Better Understand and Treat Neurological Disorders

Autor: Aishika, Datta, Deepaneeta, Sarmah, Harpreet, Kaur, Antra, Chaudhary, Namrata, Vadak, Anupom, Borah, Sudhir, Shah, Xin, Wang, Pallab, Bhattacharya

Publikováno v: Cellular and Molecular Neurobiology. 43:1019-1035

Neurological disorders have complicated pathophysiology that may involve several genetic mutations. Conventional treatment has limitations as they only treat apparent symptoms. Although, personalized medicine is emerging as a promising neuro-interven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff4194d3de6c56beb57b441dbd8a5f6
https://doi.org/10.1007/s10571-022-01242-3

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Sirtuin-1 - Mediated NF-κB Pathway Modulation to Mitigate Inflammasome Signaling and Cellular Apoptosis is One of the Neuroprotective Effects of Intra-arterial Mesenchymal Stem Cell Therapy Following Ischemic Stroke

Autor: Deepaneeta Sarmah, Aishika Datta, Harpreet Kaur, Kiran Kalia, Anupom Borah, Anne Marie Rodriguez, Dileep R. Yavagal, Pallab Bhattacharya

Publikováno v: Stem Cell Reviews and Reports. 18:821-838

Stroke results in long term serious disability that affect millions across the globe. Several clinical and preclinical studies have reinforced the therapeutic use of stem cells in stroke patients to enhance their quality of life. Previous studies fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a014706d020f98e46f8ce25ca458c9
https://doi.org/10.1007/s12015-021-10315-7

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