Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Aishah Al-Jarallah"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundHigh-density lipoprotein (HDL) protects against myocardial ischemia-reperfusion (I/R) injury. Mammalian target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2) play opposing roles in protecting against I/R injury, whereby mTORC1 appears t
Externí odkaz:
https://doaj.org/article/cce01eaec1a140d9a3c13b4c1f69781c
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1122 (2024)
Background: The pathogenesis of inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease is not well understood. This study investigated the roles and regulation of the claudin-1, -2, -3, and -4 isoforms in the pathogenesis of ulc
Externí odkaz:
https://doaj.org/article/31677c12e6c14df59152d0719b822307
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
Oxidative stress, induced by impaired insulin signaling in the brain contributes to cognitive loss in sporadic Alzheimer’s disease (sAD). This study evaluated early hippocampal oxidative stress, pre- and post-synaptic proteins in intraperitoneal (I
Externí odkaz:
https://doaj.org/article/43830fb80df742cd9029b7f1bde5f02e
Autor:
Aishah Al-Jarallah, Fawzi A. Babiker
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 497 (2024)
Background: High-density lipoprotein (HDL) protects against ischemia/reperfusion (I/R) injury via signaling through scavenger-receptor class B type-I (SR-BI) and sphingosine-1-phosphate receptors (S1PRs). We recently reported that HDL protects the he
Externí odkaz:
https://doaj.org/article/eff67974e58e4c5e9eb712976c0f53c6
Publikováno v:
Cells, Vol 12, Iss 13, p 1728 (2023)
Alzheimer’s disease (AD) is a neurological condition that affects the elderly and is characterized by progressive and irreversible neurodegeneration in the cerebral cortex [...]
Externí odkaz:
https://doaj.org/article/8afb020af0a6454e8bf1868aca3c5c65
Autor:
Aishah Al-Jarallah, Fawzi Babiker
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundHypertension is a key risk factor in the development of cardiovascular diseases. Elevation in blood pressure alters high density lipoprotein (HDL) function and composition. The exact role of HDL in cardiovascular complications observed in h
Externí odkaz:
https://doaj.org/article/a82bc7896b114e37862464917e20de1a
Publikováno v:
Cardiology Research and Practice, Vol 2019 (2019)
Background. Aging, left ventricular hypertrophy (LVH), diabetes mellitus, and pregnancy are well-recognized risk factors that increase the prevalence of cardio-ischemic events and are linked to poor clinical recovery following acute myocardial infarc
Externí odkaz:
https://doaj.org/article/ad855df548a5465ca8b7a0c9c75191b8
Autor:
Aishah Al-Jarallah, Mabayoje Oriowo
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0170792 (2017)
Increased levels of circulating sphingosine-1-phosphate (S1P) have been reported in ulcerative colitis. The objective of this study was to examine the effect of S1P on colonic smooth muscle contractility and how is it affected by colitis.Colonic infl
Externí odkaz:
https://doaj.org/article/8a231bdf81aa4ffda00ffbfa0b174336
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165777 (2016)
Accumulating evidence suggests a cardioprotective role of pacing postconditioning (PPC) maneuvers in animal models and more recently in humans. The procedure however remains to be optimized and its interaction with physiological systems remains to be
Externí odkaz:
https://doaj.org/article/55dd3c90f85049fc861ccaeff8c19da6
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106487 (2014)
HDL carries biologically active lipids such as sphingosine-1-phosphate (S1P) and stimulates a variety of cell signaling pathways in diverse cell types, which may contribute to its ability to protect against atherosclerosis. HDL and sphingosine-1-phos
Externí odkaz:
https://doaj.org/article/2aaae7c1ea5a4484b47ff4a0b8d5c7ff