Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aisha N Rekab"'
Autor:
Timothy J Walker, Eduardo Reyes-Alvarez, Brandy D Hyndman, Michael G Sugiyama, Larissa CB Oliveira, Aisha N Rekab, Mathieu JF Crupi, Rebecca Cabral-Dias, Qianjin Guo, Patricia LM Dahia, Douglas S Richardson, Costin N Antonescu, Lois M Mulligan
Publikováno v:
eLife, Vol 12 (2024)
Internalization from the cell membrane and endosomal trafficking of receptor tyrosine kinases (RTKs) are important regulators of signaling in normal cells that can frequently be disrupted in cancer. The adrenal tumor pheochromocytoma (PCC) can be cau
Externí odkaz:
https://doaj.org/article/56671c5952a34e068944e75893122071
Autor:
Eric Y. Lian, Lois M. Mulligan, Brandy D. Hyndman, Mathieu J.F. Crupi, Eduardo Reyes-Alvarez, Costin N. Antonescu, Aisha N. Rekab, Sarah M. Maritan, Serisha Moodley
Publikováno v:
Oncogene. 39(6)
The RET receptor tyrosine kinase plays important roles in regulating cellular proliferation, migration, and survival in the normal development of neural crest derived tissues. However, aberrant activation of RET, through oncogenic mutations or overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e64e2b1c2cfe87b8e62c8073198cb2
https://pubmed.ncbi.nlm.nih.gov/31645646
https://pubmed.ncbi.nlm.nih.gov/31645646
Autor:
Eric Y. Lian, Costin N. Antonescu, Susan Peng, Lois M. Mulligan, Leslie N. Bone, Aisha N. Rekab, Brandy D. Hyndman, Mathieu J.F. Crupi, Simona M. Wagner
Publikováno v:
Journal of Cell Science.
The RET receptor tyrosine kinase is implicated in normal development and cancer. RET is expressed as two isoforms, RET9 and RET51, with unique C-terminal tail sequences that recruit distinct protein complexes to mediate signals. Upon activation, RET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12e05d5402d9584d9b845f726cee726
https://doi.org/10.1242/jcs.203885
https://doi.org/10.1242/jcs.203885