Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Aisha M. Swaih"'
Autor:
Aisha M. Swaih, Carlo Breda, Korrapati V. Sathyasaikumar, Natalie Allcock, Mary E. W. Collier, Robert P. Mason, Adam Feasby, Federico Herrera, Tiago F. Outeiro, Robert Schwarcz, Mariaelena Repici, Flaviano Giorgini
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2294 (2022)
The flavoprotein kynurenine 3-monooxygenase (KMO) is localised to the outer mitochondrial membrane and catalyses the synthesis of 3-hydroxykynurenine from L-kynurenine, a key step in the kynurenine pathway (KP) of tryptophan degradation. Perturbation
Externí odkaz:
https://doaj.org/article/be2564a631cf4c249225a13d12f95bc8
Autor:
Flaviano Giorgini, Aisha M. Swaih, Anna Straatman-Iwanowska, Charalambos P. Kyriacou, Daniel C. Maddison, Mónica Alfonso-Núñez, Susanna Campesan, Natalie Allcock, Carlo Breda
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 11, p e1009129 (2020)
PLoS Genetics, Vol 16, Iss 11, p e1009129 (2020)
The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd690b874d8039bfeb5a7717f001153
http://europepmc.org/articles/PMC7654755
http://europepmc.org/articles/PMC7654755
Publikováno v:
Pathogenic mechanisms.
Background Kynurenine 3-monooxygenase (KMO), an outer mitochondrial membrane protein, catalyses the conversion of l-kynurenine to the neurotoxin 3-hydroxykynurenine (3-HK) – thereby playing a critical role in the kynurenine pathway (KP). Increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c5f059401e8ad746866c231313e8995
https://doi.org/10.1136/jnnp-2018-ehdn.27
https://doi.org/10.1136/jnnp-2018-ehdn.27
Autor:
Richard J. Johnson, Charles E. West, Steven J. Rowland, Benjamin D. Folwell, Aisha M. Swaih, Corinne Whitby, Ben E. Smith
Publikováno v:
Environmental Microbiology. 14:872-882
Naphthenic acids (NAs) are complex mixtures of carboxylic acids found in weathered crude oils and oil sands, and are toxic, corrosive and persistent. However, little is known about the microorganisms and mechanisms involved in NA degradation. We isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9af4a91188776db5329136843a39464
https://doi.org/10.1111/j.1462-2920.2011.02649.x
https://doi.org/10.1111/j.1462-2920.2011.02649.x
Autor:
Daniel C Maddison, Mónica Alfonso-Núñez, Aisha M Swaih, Carlo Breda, Susanna Campesan, Natalie Allcock, Anna Straatman-Iwanowska, Charalambos P Kyriacou, Flaviano Giorgini
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009129 (2020)
The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzym
Externí odkaz:
https://doaj.org/article/aea42986a97645b6b78125a87fbcc1a9