Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Aisha M. Mergaert"'
Autor:
Aisha M. Mergaert, Michael F. Denny, Brock Kingstad-Bakke, Mandar Bawadekar, S. Janna Bashar, Thomas F. Warner, Marulasiddappa Suresh, Miriam A. Shelef
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
The peptidylarginine deiminases (PADs) and the citrullinated proteins that they generate have key roles in innate immunity and rheumatoid arthritis, an inflammatory arthritis with antibodies that target citrullinated proteins. However, the importance
Externí odkaz:
https://doaj.org/article/6fd59b6353344d72996e41b25de3b5fa
Autor:
Aisha M. Mergaert, Zihao Zheng, Michael F. Denny, Maya F. Amjadi, S. Janna Bashar, Michael A. Newton, Vivianne Malmström, Caroline Grönwall, Sara S. McCoy, Miriam A. Shelef
Publikováno v:
Arthritis Rheumatol
Rheumatoid arthritis (RA) patients often develop rheumatoid factors (RFs), antibodies that bind IgG Fc, and anti-modified protein antibodies (AMPAs), multireactive autoantibodies that commonly bind citrullinated, homocitrullinated, and acetylated ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af855094c3a96f3464c1a721d6edde9
https://doi.org/10.1002/art.42064
https://doi.org/10.1002/art.42064
Autor:
Adrian B. McDermott, Sandeep Narpala, Aisha M Mergaert, Peter Halfmann, Ajay K. Sethi, Christopher R. Glover, Britta Flach, Sarah O’Connell, S. Janna Bashar, David H. O’Connor, Alison Taylor, Miriam A. Shelef, Tammy Armbrust, Anna S. Heffron, Yoshihiro Kawaoka, Maya F. Amjadi
Publikováno v:
medRxiv
Lasting immunity will be critical for overcoming COVID-19. However, the factors associated with the development of high titers of anti–SARS-CoV-2 Abs and how long those Abs persist remain incompletely defined. In particular, an understanding of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a681ab2254c2a8513077af04d1e102
https://doi.org/10.4049/immunohorizons.2100022
https://doi.org/10.4049/immunohorizons.2100022
Publikováno v:
Bioinformatics
Summary Peptide microarrays have emerged as a powerful technology in immunoproteomics as they provide a tool to measure the abundance of different antibodies in patient serum samples. The high dimensionality and small sample size of many experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dea87f430b06f1b285cb84fbde043a6
https://doi.org/10.1093/bioinformatics/btab162
https://doi.org/10.1093/bioinformatics/btab162
Publikováno v:
Methods in cell biology. 168
Rheumatoid arthritis is an incurable chronic inflammatory disease for which the pathophysiology is not fully understood, and treatment options are flawed. Thus, animal models are used to dissect disease pathogenesis and to develop improved therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19c93a6c9091a4a7c52987850b7553a4
https://pubmed.ncbi.nlm.nih.gov/35366979
https://pubmed.ncbi.nlm.nih.gov/35366979
Publikováno v:
Methods in Cell Biology ISBN: 9780323899451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80fc3567e29674aeadf1f3e3076cc59d
https://doi.org/10.1016/bs.mcb.2021.12.012
https://doi.org/10.1016/bs.mcb.2021.12.012
Autor:
Sara S. McCoy, Gage K. Moreno, Katarina M. Braun, Maya F. Amjadi, Srishti Gupta, David H. O’Connor, Miriam A. Shelef, Aisha M Mergaert, Thomas C. Friedrich, Nasia Safdar, S. Janna Bashar, Ryan R Adyniec
The consequences of past COVID-19 infection for personal health and long-term population immunity are only starting to be revealed. Unfortunately, detecting past infection is currently a challenge, limiting clinical and research endeavors. Widely ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db5be3470c37a72334c210e52f4428f
https://doi.org/10.1101/2021.11.02.21265750
https://doi.org/10.1101/2021.11.02.21265750
Autor:
Maya F. Amjadi, Sarah E. O’Connell, Tammy Armbrust, Aisha M. Mergaert, Sandeep R. Narpala, Peter J. Halfmann, S. Janna Bashar, Christopher R. Glover, Anna S. Heffron, Alison Taylor, Britta Flach, David H. O’Connor, Yoshihiro Kawaoka, Adrian B. McDermott, Ajay K. Sethi, Miriam A. Shelef
Publikováno v:
Immunohorizons
Lasting immunity will be critical for overcoming COVID-19. However, the factors associated with the development of high titers of anti-SARS-CoV-2 antibodies and how long those antibodies persist remain incompletely defined. In particular, an understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20281f329ea51340719a8c8f665a0c3d
https://pubmed.ncbi.nlm.nih.gov/34398806
https://pubmed.ncbi.nlm.nih.gov/34398806
Autor:
Caitlyn L. Holmes, Laura Massarenti, Ryan Rebernick, Aisha M Mergaert, Miriam A. Shelef, Steven J. Schrodi, Mandar Bawadekar, Thai Q Nguyen
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3093 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 12
International Journal of Molecular Sciences
Volume 20
Issue 12
Autoantibodies against citrullinated proteins are a hallmark of rheumatoid arthritis, a destructive inflammatory arthritis. Peptidylarginine deiminase 4 (PAD4) has been hypothesized to contribute to rheumatoid arthritis by citrullinating histones to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e46ecf491354386293d0df592b5b987
https://www.mdpi.com/1422-0067/20/12/3093
https://www.mdpi.com/1422-0067/20/12/3093
Autor:
Aisha M Mergaert, Michael A. Newton, Zihao Zheng, Alan J. Bridges, Lauren M Fahmy, Miriam A. Shelef, Caitlyn L. Holmes, Irene M. Ong, Mandar Bawadekar
Publikováno v:
Arthritis Rheumatol
OBJECTIVE Anti-citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are commonly present in rheumatoid arthritis (RA) without a clear rationale for their coexistence. Moreover, autoantibodies develop against proteins with different pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d222eee9f4529d7aaeac4d76527dc4d
https://pubmed.ncbi.nlm.nih.gov/31397047
https://pubmed.ncbi.nlm.nih.gov/31397047