Novel diagnostic approaches and management of coronary microvascular dysfunction

Autor: Graziella Pompei, Nandine Ganzorig, Christos P. Kotanidis, Mohammad Alkhalil, Carlos Collet, Aish Sinha, Divaka Perera, John Beltrame, Vijay Kunadian

Publikováno v: American Journal of Preventive Cardiology, Vol 19, Iss , Pp 100712- (2024)

The mechanism underlying ischaemic heart disease (IHD) has been primarily attributed to obstructive coronary artery disease (CAD). However, non-obstructive coronary arteries are identified in >50% of patients undergoing elective coronary angiography,

Externí odkaz: https://doaj.org/article/0495903128994fd390afc723748a24d7

The King’s Brief Interstitial Lung Disease (KBILD) questionnaire: an updated minimal clinically important difference

Autor: Sabrina Bajwah, Irene J Higginson, Toby M Maher, Aish Sinha, Amit Suresh Patel, Richard J Siegert, Elizabeth A Renzoni, Athol U Wells, Surinder S Birring

Publikováno v: BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)

Introduction The King’s Brief Interstitial Lung Disease (KBILD) is a 15-item validated health-related quality of life (HRQOL) questionnaire. The method of scoring the KBILD has recently changed to incorporate a logit-scale transformation from one t

Externí odkaz: https://doaj.org/article/318a01875b134f6dbc8e5251217b9cae

Evaluation of the causes of sex disparity in heart failure trials

Autor: Holly Morgan, Aish Sinha, Margaret Mcentegart, Suzanna Marie Hardman, Divaka Perera

Publikováno v: Morgan, H, Sinha, A, McEntegart, M, Hardman, S M & Perera, D 2022, ' Evaluation of the causes of sex disparity in heart failure trials ', Heart, vol. 108, no. 19, 320696, pp. 1547-1552 . https://doi.org/10.1136/heartjnl-2021-320696

ObjectivesCardiovascular disease is one of the leading causes of mortality and morbidity in women. Despite this, even in contemporary research, female patients are poorly represented in trials. This study aimed to explore reasons behind the sex dispa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c793d33c28013d2d45b1176352d79f6
https://doi.org/10.1136/heartjnl-2021-320696

Rapid risk stratification of acute coronary syndrome: adoption of an adapted European Society of Cardiology 0/1-hour troponin algorithm in a real-world setting

Autor: Liam S Couch, Aish Sinha, Roshan Navin, Laura Hunter, Divaka Perera, Michael S Marber, Thomas E Kaier

Publikováno v: European Heart Journal Open. 2

Aims To evaluate the clinical feasibility of implementing the 2020 ESC 0/1 hr algorithm for rapid rule-out/rule-in of acute coronary syndrome (ACS). Methods and results Data were collected retrospectively from 5496 patients in 2020 and 7363 patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5251760e407f85506580f69ec34bb7bc
https://doi.org/10.1093/ehjopen/oeac048

Ischaemia without obstructive coronary artery disease: the pathophysiology of microvascular dysfunction

Autor: Divaka Perera, Haseeb Rahman, Aish Sinha

Publikováno v: Current Opinion in Cardiology. 35:720-725

Purpose of review Nearly one-third of patients presenting with angina have unobstructed epicardial coronary arteries and evidence of coronary microvascular disease. Up until recently, the pathophysiology of coronary microvascular disease has been poo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbad33972c36f45513999cd20263771
https://doi.org/10.1097/hco.0000000000000788