P185Regulation of coagulation by zinc: characterisation of zinc-dependent heparin neutralisation by fibrinogen and histidine-rich-glycoprotein

Autor: Omar Kassaar, Siavash Khazaipoul, Alan J. Stewart, Samantha J. Pitt, R Yu, Claudia A. Blindauer, Ais Sobczak, Ramzi A. Ajjan

Publikováno v: Cardiovascular Research. 114:S50-S50

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a77e49cea4bdc6423d1dcd49f45df00b
https://doi.org/10.1093/cvr/cvy060.142

Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein.

Autor: Ackermann K; EaStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland., Khazaipoul S; Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; School of Medicine, University of St Andrews, North Haugh, St Andrews KY16 9TF, Scotland., Wort JL; EaStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland., Sobczak AIS; Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; School of Medicine, University of St Andrews, North Haugh, St Andrews KY16 9TF, Scotland., Mkami HE; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews KY16 9SS, Scotland., Stewart AJ; Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; School of Medicine, University of St Andrews, North Haugh, St Andrews KY16 9TF, Scotland., Bode BE; EaStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.; Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, Scotland.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2023 Apr 12; Vol. 145 (14), pp. 8064-8072. Date of Electronic Publication: 2023 Mar 31.

Albumin-mediated alteration of plasma zinc speciation by fatty acids modulates blood clotting in type-2 diabetes.

Autor: Sobczak AIS; School of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546., Katundu KGH; School of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.; College of Medicine, University of Malawi Blantyre Malawi., Phoenix FA; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds Leeds UK., Khazaipoul S; School of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546., Yu R; School of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.; Key Laboratory of Tibetan Medicine Research, Northwest Plateau Institute of Biology, Chinese Academy of Sciences 23 Xinning Road Xining Qinghai 810001 China., Lampiao F; College of Medicine, University of Malawi Blantyre Malawi., Stefanowicz F; Scottish Trace Element and Micronutrient Diagnostic and Research Laboratory, Department of Biochemistry NHS Greater Glasgow and Clyde Glasgow UK., Blindauer CA; Department of Chemistry, University of Warwick Coventry UK., Pitt SJ; School of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546., Smith TK; School of Biology, Biomedical Sciences Research Complex, University of St Andrews St Andrews UK., Ajjan RA; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds Leeds UK., Stewart AJ; School of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.

Publikováno v: Chemical science [Chem Sci] 2021 Feb 01; Vol. 12 (11), pp. 4079-4093. Date of Electronic Publication: 2021 Feb 01.

Reduced Plasma Magnesium Levels in Type-1 Diabetes Associate with Prothrombotic Changes in Fibrin Clotting and Fibrinolysis.

Autor: Sobczak AIS; School of Medicine, University of St Andrews, St Andrews, United Kingdom., Phoenix FA; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Pitt SJ; School of Medicine, University of St Andrews, St Andrews, United Kingdom., Ajjan RA; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom., Stewart AJ; School of Medicine, University of St Andrews, St Andrews, United Kingdom.

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2020 Feb; Vol. 120 (2), pp. 243-252. Date of Electronic Publication: 2020 Jan 03.

Total plasma magnesium, zinc, copper and selenium concentrations in type-I and type-II diabetes.

Autor: Sobczak AIS; School of Medicine, University of St Andrews, Medical and Biological Sciences Building, St Andrews, Fife, KY16 9TF, UK., Stefanowicz F; Scottish Trace Element and Micronutrient Diagnostic and Research Laboratory, Department of Clinical Biochemistry, NHS Greater Glasgow and Clyde, Glasgow, UK., Pitt SJ; School of Medicine, University of St Andrews, Medical and Biological Sciences Building, St Andrews, Fife, KY16 9TF, UK., Ajjan RA; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK., Stewart AJ; School of Medicine, University of St Andrews, Medical and Biological Sciences Building, St Andrews, Fife, KY16 9TF, UK. ajs21@st-andrews.ac.uk.

Publikováno v: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine [Biometals] 2019 Feb; Vol. 32 (1), pp. 123-138. Date of Electronic Publication: 2019 Jan 22.