Zobrazeno 1 - 10
of 4 346
pro vyhledávání: '"Airway epithelial cells"'
Autor:
Akina Mori, Marjolein Vermeer, Lenie J. van den Broek, Jeroen Heijmans, Arnaud Nicolas, Josse Bouwhuis, Todd Burton, Kazushi Matsumura, Kazuhiro Ohashi, Shigeaki Ito, Bart Kramer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Airway inflammation, a protective response in the human body, can disrupt normal organ function when chronic, as seen in chronic obstructive pulmonary disease (COPD) and asthma. Chronic bronchitis induces goblet cell hyperplasia and metaplas
Externí odkaz:
https://doaj.org/article/4acd63646b44459f875e9616d74284d6
Autor:
Arunava Ghosh, Keith L. Rogers, Samuel C. Gallant, Yong Ho Kim, Julia E. Rager, M. Ian Gilmour, Scott H. Randell, Ilona Jaspers
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Exposure to military burn pit smoke during deployment is associated with different respiratory and non-respiratory diseases. However, information linking smoke exposure to human pulmonary health is lacking. This study examined the
Externí odkaz:
https://doaj.org/article/8f0502da750347f6b28f6a5b75108904
Autor:
LI Xixuan, PENG Donghong
Publikováno v:
陆军军医大学学报, Vol 46, Iss 12, Pp 1395-1402 (2024)
Objective To investigate the effects and underlying mechanisms of NaNO2 on oxidative damage in human bronchial epithelial cells pretreated with house dust mite (HDM). Methods Human bronchial epithelial cell line 16HBE were pretreated with HDM and the
Externí odkaz:
https://doaj.org/article/4e149993f8ea46f793fee248bc9afbfe
Autor:
Xiuying Li, Sowmya P. Lakshmi, Kiyoshi Uemasu, Zachary Lane, Rajan T. Reddy, Divay Chandra, Chunbin Zou, Yu Jiang, Toru Nyunoya
Publikováno v:
COPD, Vol 21, Iss 1 (2024)
AbstractObjective: To investigate the effects of cigarette smoke (CS) on Serine/Threonine Kinase 11 (STK11) and to determine STK11’s role in CS-induced airway epithelial cell cytotoxicity.Methods: STK11 expression levels in the lung tissues of smok
Externí odkaz:
https://doaj.org/article/a59d3a06d44c46958f69c2220a69414f
Autor:
Valentina Lazzara, Paola Pinto, Serena Di Vincenzo, Maria Ferraro, Filippo Catalano, Pietro Provinzano, Elisabetta Pace, Maria Rosaria Bonsignore
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and Aim: Increased oxidative stress within the airways is associated to epithelial damage and amplification of inflammatory responses that in turn contribute to Chronic Obstructive Pulmonary Disease (COPD) progression. This study was aimed
Externí odkaz:
https://doaj.org/article/dc5f3ca45dab4f209b6fb2da2a3909f7
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Asthma comprises one of the most common chronic inflammatory conditions, yet still lacks effective diagnostic markers and treatment targets. To gain deeper insights, we comprehensively analyzed microarray datasets of airway epithelial samples from as
Externí odkaz:
https://doaj.org/article/01f05c43eee74818bea9c68d9cd412b1
Autor:
Ye Yao, Yu Yang, Ming Ji, Qingwu Qin, Kun Xu, Zhenkun Xia, Huijun Liu, Lin Yuan, Yunchang Yuan, Ling Qin, Xizi Du, Leyuan Wang, Kai Zhou, Xinyu Wu, Weijie Wang, Bei Qing, Yang Xiang, Xiangping Qu, Ming Yang, Xiaoqun Qin, Chi Liu
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract Acute asthma exacerbation refers to the progressive deterioration of asthma symptoms that is always triggered by virus infection represented by respiratory syncytial virus (RSV). After RSV infection, exaggerated Th2‐mediated pulmonary infl
Externí odkaz:
https://doaj.org/article/5c5acdb73e274cef95ac0f85cf8a7c2e
Autor:
Maria Gabriella Matera, Barbara Rinaldi, Cecilia Calabrese, Carmela Belardo, Luigino Calzetta, Mario Cazzola, Clive Page
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Airway epithelial cells (AECs) are a major component of local airway immune responses. Direct effects of type 2 cytokines on AECs are implicated in type 2 asthma, which is driven by epithelial-derived cytokines and leads to airway
Externí odkaz:
https://doaj.org/article/10bb2828b54c4c25a28aae842e455bec
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 12, Pp 1438-1443 (2023)
Objective(s): We previously revealed that scorpio and centipede (SC) improve the inflammatory response in asthma, whereas it is unclear whether ferroptosis is involved in this process.Materials and Methods: The asthmatic mouse model was established a
Externí odkaz:
https://doaj.org/article/612e198fd6274a29abbc8ab135e2531f
Autor:
Naoki Iwanaga, Ayaka Ota, Hiroki Ashizawa, Yuya Ito, Tatsuro Hirayama, Masataka Yoshida, Kazuaki Takeda, Shotaro Ide, Masato Tashiro, Naoki Hosogaya, Noriho Sakamoto, Takahiro Takazono, Kosuke Kosai, Mariko Naito, Yoshimasa Tanaka, Kazuhiro Yatera, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae
Publikováno v:
Antibiotics, Vol 13, Iss 9, p 909 (2024)
Objectives: In the present study, we aimed to clarify the mechanisms by which periodontal pathogens, particularly Prevotella intermedia, induce severe neutrophilic inflammation. In addition, we aimed to test the efficacy of macrolides, which has not
Externí odkaz:
https://doaj.org/article/a3b2725af27243d4a7def22c9111aa13