Zobrazeno 1 - 10
of 8 558
pro vyhledávání: '"Airway Hyperresponsiveness"'
Publikováno v:
Сибирский научный медицинский журнал, Vol 44, Iss 5, Pp 129-137 (2024)
The contribution of immunoregulatory cytokines to the formation of cold airway hyperresponsiveness in asthma patients is important for understanding approaches to therapy. Aim of the study was to investigate the interaction of tumor necrosis factor-a
Externí odkaz:
https://doaj.org/article/f3d17c1aa41548949b2a6fd1d0fbeb73
Autor:
Russell J. Hopp
Publikováno v:
Allergies, Vol 4, Iss 3, Pp 138-144 (2024)
Although the small airway component of chronic asthma is becoming a more important topic, its impact in the daily assessment of pediatric asthma is limited. The intrinsic airway autonomic control in asthma suggests some potential mechanisms by which
Externí odkaz:
https://doaj.org/article/fa4cf08594ad45c59a91a26da1158fe4
Autor:
Benoit Allard, Olga Ousova, Zhanna Savitskaya, Hannah Levardon, Elise Maurat, Marilyne Campagnac, Thomas Trian, Patrick Berger
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background While asthma exacerbations remain a major challenge in patient management, few animal models exist to explore the underlying mechanisms. Here, we established an animal model of asthma that can be used to study pathophysiological m
Externí odkaz:
https://doaj.org/article/c1b8c53d13f542be8cb337dd885642b2
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Shortening of airway smooth muscle and bronchoconstriction are pathognomonic for asthma. Airway shortening occurs through calcium-dependent activation of myosin light chain kinase, and RhoA-dependent calcium sensitization, which inhibits myo
Externí odkaz:
https://doaj.org/article/36e01c6825cf4c16a4d7be891eebbe2d
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Fibroblast differentiation to a myofibroblast phenotype is a feature of airway remodeling in asthma. Lung fibroblasts express the integrin receptor α4β7 and fibronectin induces myofibroblast differentiation via this receptor. Ob
Externí odkaz:
https://doaj.org/article/652d5d37d87d4c24a742b32c74f16008
Autor:
Tomoko Tajiri, Motohiko Suzuki, Hirono Nishiyama, Yoshiyuki Ozawa, Ryota Kurokawa, Norihisa Takeda, Keima Ito, Kensuke Fukumitsu, Yoshihiro Kanemitsu, Yuta Mori, Satoshi Fukuda, Takehiro Uemura, Hirotsugu Ohkubo, Masaya Takemura, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Kenji Izuhara, Akio Niimi
Publikováno v:
Allergology International, Vol 73, Iss 3, Pp 406-415 (2024)
Background: Dupilumab has clinical effects in patients with moderate-to-severe asthma. When considering interleukin (IL)-4 and IL-13 signaling, effects of dupilumab on airway mucus hypersecretion and airway remodeling are expected, but they have been
Externí odkaz:
https://doaj.org/article/54aaf13e615b4d6ba77f3fe4a3a4bbae
Autor:
Su Ji Kim, MD, Youn Joo Choi, MD, Man Yong Han, MD, PhD, Il Tae Hwang, MD, PhD, Hey-Sung Baek, MD, PhD
Publikováno v:
World Allergy Organization Journal, Vol 17, Iss 11, Pp 100991- (2024)
Background: Periostin and human chitinase-3-like protein 1 (YKL-40) have been suggested to be involved in the development of airway fibrosis and remodeling. This study aimed to investigate the relationship between serum periostin levels and airway hy
Externí odkaz:
https://doaj.org/article/4965f6a32a9145b8a1f5333099d03fa1
Autor:
Salik Hussain, Nairrita Majumder, Md Habibul Hasan Mazumder, Sara E. Lewis, Olanrewaju Olapeju, Murugesan Velayutham, Md Shahrier Amin, Kathleen Brundage, Eric E. Kelley, Jeroen Vanoirbeek
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103330- (2024)
The ability of air pollution to induce acute exacerbation of asthma is well documented. However, the ability of ozone (O3), the most reactive gaseous component of air pollution, to function as a modulator during sensitization is not well established.
Externí odkaz:
https://doaj.org/article/baacc4854cc84a069ee556f502f997ac
Autor:
Andrea Portacci, Ilaria Iorillo, Leonardo Maselli, Monica Amendolara, Vitaliano Nicola Quaranta, Silvano Dragonieri, Giovanna Elisiana Carpagnano
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4271-4285 (2024)
Galectins are a group of β-galactoside-binding proteins with several roles in immune response, cellular adhesion, and inflammation development. Current evidence suggest that these proteins could play a crucial role in many respiratory diseases such
Externí odkaz:
https://doaj.org/article/e9a8dec8dc124d57a6e742f12f97a539
Autor:
Akiko Sano, Takenori Kozuka, Nanase Watatani, Yuuki Kunita, Yoshiyuki Kawabata, Kyuya Gose, Ken Shirahase, Kazuya Yoshikawa, Ryo Yamazaki, Yusaku Nishikawa, Takashi Omori, Osamu Nishiyama, Takashi Iwanaga, Hiroyuki Sano, Ryuta Haraguchi, Yuji Tohda, Hisako Matsumoto
Publikováno v:
Allergology International, Vol 73, Iss 2, Pp 231-235 (2024)
Background: Obstructive sleep apnea (OSA) is one of the major co-morbidities and aggravating factors of asthma. In OSA-complicated asthma, obesity, visceral fat, and systemic inflammation are associated with its severity, but the role of bronchial hy
Externí odkaz:
https://doaj.org/article/67a4fe33267247b68a1eede4e9ee62d1