Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Aire Laine"'
Publikováno v:
Journal of Functional Foods, Vol 25, Iss , Pp 160-173 (2016)
The angiotensin I-converting enzyme (ACE) inhibitory and antihypertensive properties of potato and rapeseed protein-derived peptides were investigated. Proteins from potato tubers were digested by autolysis and rapeseed meal proteins were hydrolysed
Externí odkaz:
https://doaj.org/article/f1d2da2fadb44334ad5729cc2809dc5d
Publikováno v:
Luminescence. 26:251-258
Human leukemic THP-1 promonocytes are widely used as a model for peripheral blood monocytes. However, superoxide production during respiratory burst (RB) of non-differentiated THP-1 (nd-THP-1) cells is very low. Here we present a rapid and low-cost m
Autor:
Kalervo Väänänen, Johanna Dahllund, L. Kangas, Mikko Koskinen, Natalia Cockcroft, Aire Laine, Zhiqi Peng, Kari Hemminki, Pirkko Härkönen, Qiang Qu, Huili Zheng
Publikováno v:
Endocrinology. 141:809-820
FC1271a is a novel triphenylethylene compound with a tissue-selective profile of estrogen agonistic and weak antagonistic effects. It specifically binds to the estrogen receptor alpha and beta with affinity closely similar to that of toremifene and t
Autor:
Mari Kielosto, Terho O. Eloranta, Essi Kääriäinen, Michael J. Birrer, Olli A. Jänne, Aire Laine, Aino Paasinen-Sohns, Erkki Hölttä
Publikováno v:
The Journal of Cell Biology
All mammalian cells absolutely require polyamines (putrescine, spermidine, and spermine) for growth. Here we show that the overexpression of cDNA for S-adenosylmethionine decarboxylase (AdoMetDC), the main regulatory enzyme in the biosynthesis of hig
Publikováno v:
JNCI Journal of the National Cancer Institute. 85:1412-1418
BACKGROUND Antiestrogens inhibit the stimulative effects of estrogens on breast cancer growth, but the mechanism(s) by which they trigger tumor regression are not completely understood. Growth retardation and tumor regression can be achieved by enhan
Publikováno v:
European Journal of Nuclear Medicine. 18:339-345
We have evaluated the effects of tumour mass and circulating antigen (prostatic acid phosphatase, PAP) on the biodistribution and the incorporation of111In-labelled F(ab′)2 monoclonal antibody (MoAb) fragments directed against human PAP into human
Autor:
Jukka Hiltunen, Tuomo Nikula, Aire Laine, Sven-Erik Strand, Torsten Wahlström, Kalevi Kairemo, Pirkko Penttilä, Kaj Ljunggren
Publikováno v:
Acta oncologica (Stockholm, Sweden). 32(7-8)
Tumor stroma contains much fibrin, and so monoclonal antifibrin antibody can accumulate in tumors. We treated nude mice bearing human ovarian carcinoma xenografts with 90Y-labeled monoclonal antifibrin antibody Fab fragments administered intratumoral
Publikováno v:
European Journal of Nuclear Medicine. 18
Publikováno v:
International journal of cancer. 49(4)
Amplification and enhanced expression of the erbB2/HER-2/neu gene has been associated with an increased growth rate and poor prognosis of human breast cancer. We have studied the relationship between erbB2 expression and the regulation of cell growth
Autor:
Kari Y. H. Lagerspetz, Aire Laine
Publikováno v:
Comparative Biochemistry and Physiology Part A: Physiology. 87:873-876
1. 1-5 mM n-hexanol added to the outer (mucosal) medium of isolated skin of the frog Rana temporaria increases the short circuit current (Isc) across it. 2. This effect shows a saturable dependency on the outer sodium concentration, also when NaCl is