Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Aiqiu Zhao"'
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
Previous studies suggest that sarcolemmal potassium currents play important roles in cardiac hypertrophy. IGF-1 contributes to cardiac hypertrophy via activation of PI3K/Akt signaling. However, the relationships between IGF-1, PI3K/Akt signaling and
Externí odkaz:
https://doaj.org/article/d5f9e0bad67f4565ad7313cf1da8c48b
Autor:
Aiqiu Zhao, Georges E. Haddad, Graham G. Laurence, Majd Hajj-MoussaM. Hajj-Moussa, Zikiar Alvin, Bernell R. Coleman
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Summary Background Early development of cardiac hypertrophy may be beneficial but sustained hypertrophic activation leads to myocardial dysfunction. Regulation of the repolarizing currents can be modulated by the activation of humoral factors, such a
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 295:H1834-H1845
The potassium channels IK and IK1, responsible for the action potential repolarization and resting potential respectively, are altered during cardiac hypertrophy. The activation of insulin-like growth factor-I (IGF-I) during hypertrophy may affect ch
Autor:
Layron O. Long, Chiledum Ahaghotu, Carolina Bonilla, Trevor Tullock, William Aiken, Frankly Bennett, Tshela Mason, Vincent L. Freeman, Weidong Chen, Aiqiu Zhao, Kathleen Coard, Rick A. Kittles, Aoua Coulibaly
Publikováno v:
The Prostate. 66:546-556
BACKGROUND The E-cadherin (CDH1) gene has been implicated in prostate cancer (PCA) risk, however, the exact mechanism is unknown. Several polymorphisms, such as the C/A variant −160 base pairs from the transcription start site, in the CDH1 gene pro
Autor:
Jing Ma, Aiqiu Zhao, Fang Hua, Georges E. Haddad, I. William Browder, Xiang Gao, Tuanzhu Ha, Chuanfu Li, Yuehua Li, David L. Williams, Race L. Kao, Jim Kelley
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H985-H994
In this study, we evaluated whether blocking myeloid differentiation factor-88 (MyD88) could decrease cardiac myocyte apoptosis following pressure overload. Adenovirus expressing dominant negative MyD88 (Ad5-dnMyD88) or Ad5-green fluorescent protein
Autor:
Xiang Gao, Georges E. Haddad, Aiqiu Zhao, Fang Hua, Tuanzhu Ha, David L. Williams, Jinag Ma, Chuanfu Li, Yuehua Li, Race L. Kao, Jim Kelley, I. William Browder
Publikováno v:
Cardiovascular Research. 68:224-234
Objective: We have previously demonstrated that nuclear factor kappa B (NFκB) activation is needed for the development of cardiac hypertrophy in vivo. NFκB is a downstream transcription factor in the Toll-like receptor (TLR)-mediated signaling path
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H695-H704
ANG II plays a major role in development of cardiac hypertrophy through its AT1receptor subtype, whereas angiotensin-converting enzyme (ACE) inhibitors are effective in reversing effects of ANG II on the heart. The objective of this study was to inve
Publikováno v:
The FASEB Journal. 24
Publikováno v:
The FASEB Journal. 24
Publikováno v:
The FASEB Journal. 24