Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Aiping Ma"'
Autor:
Aiping Ma, Guangdong Wang, Yan Du, Weixi Guo, Jiaxi Guo, Yi Hu, Dongyu Bai, Huiping Huang, Lianjin Zhuang, Jinhan Chen, Qun Liu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundChronic obstructive pulmonary disease (COPD) coexisting with lung cancer is associated with severe mortality and a worse prognosis. Inflammation plays an important role in common pathogenic pathways and disease progression. However, a few s
Externí odkaz:
https://doaj.org/article/5920439dfd9a402f991c0188bf7a07a3
Autor:
Guangdong Wang, Aiping Ma, Liang Zhang, Jiaxi Guo, Qun Liu, Frank Petersen, Zhanxiang Wang, Xinhua Yu
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Acute exacerbations show a significant impact on disease morbidity and mortality in chronic obstructive pulmonary disease (COPD). In contrast to stable COPD, the association of smoking status with clinical and laboratory characteristics in patients w
Externí odkaz:
https://doaj.org/article/274312205a8d4d489ec35f265baa8b83
Autor:
Aiping Ma, Liang Zhang, Xiaokai Ye, Jing Chen, Jie Yu, Liangjin Zhuang, Chaohang Weng, Frank Petersen, Zhanxiang Wang, Xinhua Yu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectivesThe coordinated immune response of the host is the key of the successful combat of the body against SARS-CoV-2 infection and is decisive for the development and progression of COVID-19. In this study, we aimed to investigate whether the imm
Externí odkaz:
https://doaj.org/article/d134e2742d764eba885df54c9baa37c1
Autor:
Yao-Song Gui, Lianmei Wang, Xinlun Tian, Xue Li, Aiping Ma, Weixun Zhou, Ni Zeng, Ji Zhang, Baiqiang Cai, Hongbing Zhang, Jing-Yu Chen, Kai-Feng Xu
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138625 (2015)
The mammalian target of rapamycin (mTOR) signaling pathway in pulmonary fibrosis was investigated in cell and animal models. mTOR overactivation in alveolar epithelial cells (AECs) was achieved in the conditional and inducible Tsc1 knock-down mice SP
Externí odkaz:
https://doaj.org/article/2e2c361516c941f1adf7b9bea34d94ef
Autor:
Yao-Song Gui, Lianmei Wang, Xinlun Tian, Ruie Feng, Aiping Ma, Baiqiang Cai, Hongbing Zhang, Kai-Feng Xu
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46076 (2012)
Although several Cre-loxP-based gene knockout mouse models have been generated for the study of gene function in alveolar epithelia in the lung, their applications are still limited. In this study, we developed a SPC-Cre-ER(T2) mouse model, in which
Externí odkaz:
https://doaj.org/article/36d68d59fca14ef5acac3a04ad9d4994
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:2458-2467
Background: Lung cancer is one of the leading causes of cancer-related deaths worldwide. Platycodin D (PD), a major pharmacological constituent from the Chinese medicinal herb named Platycodonis Radix, has shown potent anti-tumor activity. Also, it i
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Hemoglobin (Hb) Lepore is a rare deletional δβ-thalassemia caused by the fusion between delta-beta genes, and cannot be identified by traditional thaltassemia gene testing technology. The aim of this study was to conduct molecular diagnosi
Externí odkaz:
https://doaj.org/article/cdf33d28c58940f4ae9513fdd204a17c
Autor:
Ji Zhang, Yi Hu, Huiping Huang, Qun Liu, Yang Du, Guangdong Wang, Dehong Gao, Weixi Guo, Zhanxiang Wang, Aiping Ma
Fibroblast-to-myofibroblast transdifferentiation and myofibroblast hyperproliferation play a major role in Idiopathic pulmonary fibrosis (IPF). It was also reported that mTOR signaling pathway and SIRT6 have a critical role in pulmonary fibrosis. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7cf14a5336f3938c148d5b9bdf5e44b
https://doi.org/10.21203/rs.3.rs-1149371/v1
https://doi.org/10.21203/rs.3.rs-1149371/v1
Publikováno v:
Journal of Cancer
It is known that mammalian target of rapamycin (mTOR) signaling plays an important role in NSCLC cells proliferation. Torin2 is a second-generation ATP-competitive inhibitor which is selective for mTOR activity. In this study, we investigated whether
Autor:
Xiaohong Zhang, Fan Hong, Tingting Qin, Zhengyan Zhu, Aiping Ma, Xiongjie Zhang, Yang Xu, Xiaohong Xu
Publikováno v:
The American Journal of the Medical Sciences. 359:123-129
Background The poor outcomes in epithelial ovarian cancer necessitate new treatments. In this work, we systematically analyzed the inhibitory effects of ivermectin and the molecular mechanism of its action in ovarian cancer. Methods The effects of iv