Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Aiping Duan"'
Autor:
Hong Wang, Aiping Duan, Jing Zhang, Qi Wang, Yuexian Xing, Zhaohui Qin, Zhihong Liu, Jingping Yang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to
Externí odkaz:
https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16
Autor:
Aiping Duan, Hong Wang, Yan Zhu, Qi Wang, Jing Zhang, Qing Hou, Yuexian Xing, Jinsong Shi, Jinhua Hou, Zhaohui Qin, Zhaohong Chen, Zhihong Liu, Jingping Yang
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Cell type-specific transcriptional programming results from the combinatorial interplay between the repertoire of active regulatory elements. Disease-associated variants disrupt such programming, leading to altered expression of d
Externí odkaz:
https://doaj.org/article/989f32885b0f453ba0bb141152e08760
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Lipid metabolism plays a basic role in renal physiology, especially in tubules. Hypoxia and hypoxia-induced factor (HIF) activation are common in renal diseases; however, the relationship between HIF and tubular lipid metabolism is poorly understood.
Externí odkaz:
https://doaj.org/article/ce21bcd5507b406792a56968442c902b
Autor:
Yang Hu, Tangsong Zhu, Shaohui gao, Aiping Duan, Weisong Qin, Zhihong Liu, Ruinian Hua, Qiuhong Zhang, Hao Bao
Background: Chronic kidney disease (CKD) is the most common renal disease. Renal interstitial fibrosis (RIF) is an important marker of the progression of chronic kidney disease. Epithelial-interstitial transformation (EMT) and the release of inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79b970369556f146186624ccfd7fccf1
https://doi.org/10.21203/rs.3.rs-2360595/v1
https://doi.org/10.21203/rs.3.rs-2360595/v1
Autor:
Song Jiang, Masaru Motojima, Qing Hou, Aiping Duan, Zhihong Liu, Jinhua Hou, Difei Zhang, Jingping Yang, Mingchao Zhang, Yu Pan, Tsutomu Kume, Jing-Song Shi, Zhaohui S. Qin
Publikováno v:
J Am Soc Nephrol
Background Transcriptional programs control cell fate, and identifying their components is critical for understanding diseases caused by cell lesion, such as podocytopathy. Although many transcription factors (TFs) are necessary for cell-state mainte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfe4f6ba673ea859f2379e071ed0ee3
https://doi.org/10.1681/asn.2020081177
https://doi.org/10.1681/asn.2020081177
Autor:
Aiping Duan, Qi Wang, Zhaohui S. Qin, Hong Wang, Jingping Yang, Zhihong Liu, Yuexian Xing, Jing Zhang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Communications Biology
Communications Biology
Elucidating transcription mediated by the glucocorticoid receptor (GR) is crucial for understanding the role of glucocorticoids (GCs) in the treatment of diseases. Podocyte is a useful model for studying GR regulation because GCs are the primary medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1d847df44af236ee4ceb8f13357a24
https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16
https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16
Publikováno v:
The FEBS Journal. 288:5446-5458
Cellular injury caused by stimuli plays an important role in the progression of various diseases including acute and chronic kidney diseases. The dynamic transcriptional regulation responding to stimuli underlies the important mechanism of injury. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f07e59a17bbbdd52e1b2693dc1ebcbe
https://doi.org/10.1111/febs.15818
https://doi.org/10.1111/febs.15818
Autor:
Jinsong Shi, Aiping Duan, Zhaohui S. Qin, Qi Wang, Jinhua Hou, Zhaohong Chen, Qing Hou, Zhihong Liu, Hong Wang, Jingping Yang, Yuexian Xing, Yan Zhu, Jing Zhang
Publikováno v:
BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-13 (2021)
BMC Biology, Vol 19, Iss 1, Pp 1-13 (2021)
BackgroundCell type-specific transcriptional programming results from the combinatorial interplay between the repertoire of active regulatory elements. Disease-associated variants disrupt such programming, leading to altered expression of downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fca4a394916cd030fad0b1f875cd09d
https://doi.org/10.1186/s12915-021-00977-7
https://doi.org/10.1186/s12915-021-00977-7
Autor:
Aiping Duan, Wang, Hong, Zhu, Yan, Wang, Qi, Zhang, Jing, Hou, Qing, Yuexian Xing, Jinsong Shi, Jinhua Hou, Zhaohui Qin, Zhaohong Chen, Zhihong Liu, Yang, Jingping
Additional file 1: Fig. Correlation of replications for histione modifications ChIP-seq. Fig. S2. Histone modifications and RNA tracks for HK2 cell line and whole kidney. Fig. S3. Histone modification tracks at DAB2 enhancer. Fig. S4. Immunochemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25887c6443bbbc2f6825444b3a1ab9d