Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Aiping Bai"'
Autor:
Aiping Bai, Alan Moss, Sonja Rothweiler, Maria Serena Longhi, Yan Wu, Wolfgang G. Junger, Simon C. Robson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/ef28daa6ed6f4fb999a3ed66d699f3af
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215770 (2019)
The purpose of this study was to determine the profile of bioactive sphingolipids in xenograft mouse tissues of head and neck squamous cell carcinoma. We utilized UHPLC-MS/MS to determine the profile of full set of ceramides, sphingosine, and sphingo
Externí odkaz:
https://doaj.org/article/0843b86616b6499da992bb54151582ab
Autor:
Aiping Bai, Cungui Mao, Russell W Jenkins, Zdzislaw M Szulc, Alicja Bielawska, Yusuf A Hannun
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177805 (2017)
Acid ceramidase, which catalyzes ceramide hydrolysis to sphingosine and free fatty acid mainly in the lysosome, is being recognized as a potential therapeutic target for cancer. B13 is an effective and selective acid ceramidase inhibitor in vitro, bu
Externí odkaz:
https://doaj.org/article/3ce94aae187747b5aa33eeef1dbeb586
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86881 (2014)
BACKGROUND:AMP-activated protein kinase (AMPK) is an important enzyme in regulation of cellular energy homeostasis. We have previously shown that AMPK activation by 5-aminoimidazole-4-carboxamide (AICAR) results in suppression of immune responses, in
Externí odkaz:
https://doaj.org/article/38581de316b74c5a89328fad22657a13
Autor:
Maria Serena Longhi, Alan Moss, Aiping Bai, Yan Wu, Huang Huang, Adam Cheifetz, Francisco J Quintana, Simon C Robson
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87956 (2014)
Induced regulatory T-cells (iT-reg) and T helper type 17 (Th17) in the mouse share common CD4 progenitor cells and exhibit overlapping phenotypic and functional features. Here, we show that human Th17 cells endowed with suppressor activity (supTh17)
Externí odkaz:
https://doaj.org/article/34b7a9aeeec246f993a1a00c43a73f38
Autor:
Shu Bian, Xiaofeng Sun, Aiping Bai, Chunqing Zhang, Linglin Li, Keiichi Enjyoji, Wolfgang G Junger, Simon C Robson, Yan Wu
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60184 (2013)
Extracellular adenosine triphosphate (ATP) functions as a novel danger signal that boosts antitumor immunity and can also directly kill tumor cells. We have previously reported that chronic exposure of tumor cells to ATP provokes P2X7-mediated tumor
Externí odkaz:
https://doaj.org/article/7326675dae354327b9332cc4b9cf4ed2
Figure S1. KSHV infection up-regulates SphK2 expression from endothelial cells. Figure S2. ABC294640 significantly increases endogenous total ceramides/dh-ceramides from TIVE-LTC but not TIVE cells. Figure S3. Chloroquine effectively blocks autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bf9689a004d4e732eb93db3cacb26c
https://doi.org/10.1158/1535-7163.22503679
https://doi.org/10.1158/1535-7163.22503679
Autor:
Houjian Cai, Scott D. Pegan, Iryna Lebedyeva, Alicja Bielawska, Zdzislaw M. Szulc, James S. Norris, Y. George Zheng, Zanna Beharry, Thomas Albers, Aiping Bai, Zhen Han, Essilvo Sulejmani, Qianjin Li, Octavia Goodwin, Omar Awad Alsaidan, Sungjin Kim
Figure S1. Knockdown of NMT1 by shRNA-NMT1 inhibits Src myristoylation and proliferation of prostate cancer cells. Figure S2. Knockdown of Src and Fyn kinase inhibits the growth of prostate cancer cells. Figure S3. The contribution of myristoylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278376ee2ab1a539f486aaacd526a3d0
https://doi.org/10.1158/0008-5472.22416945
https://doi.org/10.1158/0008-5472.22416945
Autor:
Houjian Cai, Scott D. Pegan, Iryna Lebedyeva, Alicja Bielawska, Zdzislaw M. Szulc, James S. Norris, Y. George Zheng, Zanna Beharry, Thomas Albers, Aiping Bai, Zhen Han, Essilvo Sulejmani, Qianjin Li, Octavia Goodwin, Omar Awad Alsaidan, Sungjin Kim
Data collection and refinement statistics (molecular replacement)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfaaea0e4d61af9d6f5471820be0f13
https://doi.org/10.1158/0008-5472.22416924.v1
https://doi.org/10.1158/0008-5472.22416924.v1
Autor:
Houjian Cai, Scott D. Pegan, Iryna Lebedyeva, Alicja Bielawska, Zdzislaw M. Szulc, James S. Norris, Y. George Zheng, Zanna Beharry, Thomas Albers, Aiping Bai, Zhen Han, Essilvo Sulejmani, Qianjin Li, Octavia Goodwin, Omar Awad Alsaidan, Sungjin Kim
Loss of myristoylation in Src kinase inhibits its interaction with androgen receptor (AR) and activation of AR down-stream signaling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52beac319bff9c691e689b287eb25010
https://doi.org/10.1158/0008-5472.22416939
https://doi.org/10.1158/0008-5472.22416939