Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Aintzane García‐Bea"'
Autor:
Chaejin Kim, Valentina Lo Re, Monica Rodriguez, John C. Lukas, Nerea Leal, Cristina Campo, Aintzane García‐Bea, Elena Suarez, Stephan Schmidt, Valvanera Vozmediano
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 1006-1017 (2021)
Abstract The objective of this study was to evaluate bilastine dosing recommendations in older adults and overcome the limitation of insufficient data from phase I studies in this underrepresented population. This was achieved by integrating bilastin
Externí odkaz:
https://doaj.org/article/2409e3bfd14a4f6db9eeca7e4cc482ea
Autor:
Rebeca Diez-Alarcia, Carolina Muguruza, Guadalupe Rivero, Aintzane García-Bea, Vanessa Gómez-Vallejo, Luis F. Callado, Jordi Llop, Abraham Martín, J. Javier Meana
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The status of serotonin 5HT2A receptors (5HT2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about 5HT2AR densit
Externí odkaz:
https://doaj.org/article/ab7a5744879b4c13a57c83edf01eeb7b
Autor:
Stephan Schmidt, Cristina Campo, Nerea Leal, Aintzane García-Bea, Valvanera Vozmediano, Valentina Lo Re, John C. Lukas, Chaejin Kim, Elena Suarez, Monica Rodriguez
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
Addi. Archivo Digital para la Docencia y la Investigación
instname
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 1006-1017 (2021)
Addi. Archivo Digital para la Docencia y la Investigación
instname
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 1006-1017 (2021)
The objective of this study was to evaluate bilastine dosing recommendations in older adults and overcome the limitation of insufficient data from phase I studies in this underrepresented population. This was achieved by integrating bilastine physico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86450b1de363cc6dfe49dd101c9c56c6
https://doi.org/10.1002/psp4.12671
https://doi.org/10.1002/psp4.12671
Autor:
Anahí Yáñez, Aintzane García-Bea, Luis Labeaga, Monica Rodriguez, Valvanera Vozmediano, Cristina Campo, Zoltán Novák
Publikováno v:
European Journal of Pediatrics
Bilastine, a second-generation antihistamine, is approved in Europe for the treatment of allergic rhinoconjunctivitis and urticaria in adults and children aged ≥ 6 years. Pharmacokinetic data for children aged 6–11 years were extracted post hoc f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6a9d4b05a7d04e016f2ac8c118e0f4
http://europepmc.org/articles/PMC7160087
http://europepmc.org/articles/PMC7160087
Autor:
Aintzane García-Bea, José Ramón Azanza, Cristina Campo, Luis Labeaga, Belén Sádaba, Román Valiente
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 45:265-272
Bilastine is a non-sedating H1 antihistamine indicated for the treatment of allergic rhinoconjunctivitis and urticaria. The aim of this trial was to assess the bioequivalence of three novel pediatric oral formulations of bilastine. An open label, ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d777e5d88939b2cd46a3002730e247
https://doi.org/10.1007/s13318-019-00596-2
https://doi.org/10.1007/s13318-019-00596-2
Autor:
Patricia Miranda-Azpiazu, Iria Brocos-Mosquera, Luis F. Callado, Brendan Kelly, Aaron P. Keogh, Helene B. Mihigo, Michela McMullan, Aintzane García-Bea, Fernando Rodriguez, Isabel Rozas
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Compounds with excellent receptor engagement displaying alpha(2)-AR antagonist activity are useful not only for therapeutic purposes (e.g. antidepressants), but also to help in the crystallization of this particular GPCR. Therefore, based on our broa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00098d673f7bf3bff0e2233d76891f00
http://hdl.handle.net/10810/50321
http://hdl.handle.net/10810/50321
Autor:
Aintzane, García-Bea, Patricia, Miranda-Azpiazu, Carolina, Muguruza, Sara, Marmolejo-Martinez-Artesero, Rebeca, Diez-Alarcia, Ane M, Gabilondo, Luis F, Callado, Benito, Morentin, Javier, González-Maeso, J Javier, Meana
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 29(12)
Serotonin 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f7dbf8a4a935d64d3b0cab299175467
https://pubmed.ncbi.nlm.nih.gov/31734018
https://pubmed.ncbi.nlm.nih.gov/31734018
Autor:
Carolina Muguruza, Aintzane García-Bea, Luis F. Callado, Rebeca Diez-Alarcia, Patricia Miranda-Azpiazu, Benito Morentin, Sara Marmolejo-Martinez-Artesero, Javier González-Maeso, Ane M. Gabilondo, J. Javier Meana
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
instname
Serotonin 5-HT2A receptors (5-HT(2A)Rs) have been implicated in schizophrenia. However, postmortem studies on 5-HT(2A)Rs expression and functionality in schizophrenia are scarce. The 5-HT2AR mRNA and immunoreactive protein expression were evaluated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f0075557243c9ce1e5ba1fa6c735e7
http://hdl.handle.net/10810/41959
http://hdl.handle.net/10810/41959
Autor:
Isabel Rozas, Patricia Miranda-Azpiazu, Aintzane García-Bea, Michela McMullan, Luis F. Callado
Publikováno v:
European Journal of Medicinal Chemistry. 123:48-57
In this paper we report the design, synthesis and pharmacological evaluation of new N-substituted 2-amino-1,4-dihydroquinazolines, 2-amino-1,4-dihydropyridopyrimidines and 2-amino-4,5-dihydro-1,3-benzodiazepines as α2-adrenoceptors ligands. Computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee5a304d9ae5bff3fd59e4633b727fc
https://doi.org/10.1016/j.ejmech.2016.07.011
https://doi.org/10.1016/j.ejmech.2016.07.011
Autor:
Yan Jiang, Carolina Muguruza, Daisuke Ibi, Carlos R. Escalante, Maryum K. Ijaz, Daniel J. Christoffel, Schahram Akbarian, Alexey Kozlenkov, Scott J. Russo, Nebojsa Kezunovic, Vishaka Santosh, Jeremy Seto, Javier González-Maeso, Terrell Holloway, Supriya A Gaitonde, Luis F. Callado, J. Javier Meana, Mario de la Fuente Revenga, José L. Moreno, Stella Dracheva, Mitsumasa Kurita, Grace E. Mosley, George W. Huntley, Juan F. López-Giménez, Aintzane García-Bea, Yongchao Ge, Justin M. Saunders
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Ibi, Daisuke et al.
Antipsychotic drugs remain the standard for schizophrenia treatment. Despite their effectiveness in treating hallucinations and delusions, prolonged exposure to antipsychotic medications leads to cognitive deficits in both sc
Antipsychotic drugs remain the standard for schizophrenia treatment. Despite their effectiveness in treating hallucinations and delusions, prolonged exposure to antipsychotic medications leads to cognitive deficits in both sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66464623ccb19b82f6f131f694dde974
https://pubmed.ncbi.nlm.nih.gov/28783139
https://pubmed.ncbi.nlm.nih.gov/28783139