Nanoscale Tweezers for Single Cell Biopsies

Autor: Paulose Nadappuram, B, Cadinu, P, Barik, A, Ainscough, AJ, Devine, MJ, Kang, M, Gonzalez-Garcia, J, Kittler, JT, Willison, KR, Vilar, R, Actis, P, Wojciak-Stothard, B, Oh, S-H, Ivanov, AP, Edel, JB

Much of the functionality of multi-cellular systems arises from the spatial organisation and dynamic behaviours, both within and between cells. Current single-cell genomic methods only provide a transcriptional “snapshot” of individual cells. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::067deb377a9badf03a718b7579009784
https://eprints.whiterose.ac.uk/136471/13/s41565-018-0315-8.pdf

Embedding Biomimetic Vascular Networks via Coaxial Sacrificial Writing into Functional Tissue.

Autor: Stankey PP; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Kroll KT; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Ainscough AJ; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Reynolds DS; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Elamine A; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Fichtenkort BT; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Uzel SGM; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Lewis JA; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Sep; Vol. 36 (36), pp. e2401528. Date of Electronic Publication: 2024 Aug 02.

An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis.

Autor: Ainscough AJ; National Heart and Lung Institute, Imperial College London, London, UK.; Department of Chemistry, Imperial College London, London, UK., Smith TJ; Department of Chemistry, Imperial College London, London, UK., Haensel M; National Heart and Lung Institute, Imperial College London, London, UK., Rhodes CJ; National Heart and Lung Institute, Imperial College London, London, UK., Fellows A; National Heart and Lung Institute, Imperial College London, London, UK., Whitwell HJ; National Phenome Centre and Imperial Clinical Phenotyping Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Vasilaki E; National Heart and Lung Institute, Imperial College London, London, UK., Gray K; Emerging Innovations Unit, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Freeman A; Emerging Innovations Unit, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Howard LS; National Heart and Lung Institute, Imperial College London, London, UK., Wharton J; National Heart and Lung Institute, Imperial College London, London, UK., Dunmore B; Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Royal Papworth Hospitals, Cambridge, UK., Upton PD; Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Royal Papworth Hospitals, Cambridge, UK., Wilkins MR; National Heart and Lung Institute, Imperial College London, London, UK., Edel JB; Department of Chemistry, Imperial College London, London, UK., Wojciak-Stothard B; National Heart and Lung Institute, Imperial College London, London, UK. b.wojciak-stothard@imperial.ac.uk.

Publikováno v: Communications biology [Commun Biol] 2022 Nov 07; Vol. 5 (1), pp. 1192. Date of Electronic Publication: 2022 Nov 07.

Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.

Autor: Sindi HA; National Heart and Lung Institute, Imperial College London, London, UK.; University of Jeddah, College of Science, Department of Biology, Jeddah, Saudi Arabia., Russomanno G; National Heart and Lung Institute, Imperial College London, London, UK., Satta S; National Heart and Lung Institute, Imperial College London, London, UK., Abdul-Salam VB; National Heart and Lung Institute, Imperial College London, London, UK., Jo KB; National Heart and Lung Institute, Imperial College London, London, UK., Qazi-Chaudhry B; Department of Physics, King's College London UK, London, UK., Ainscough AJ; National Heart and Lung Institute, Imperial College London, London, UK., Szulcek R; Amsterdam UMC, VU University Medical Center, Department of Pulmonary Diseases, Amsterdam Cardiovascular Sciences (ACS), Amsterdam, The Netherlands., Bogaard HJ; Amsterdam UMC, VU University Medical Center, Department of Pulmonary Diseases, Amsterdam Cardiovascular Sciences (ACS), Amsterdam, The Netherlands., Morgan CC; National Heart and Lung Institute, Imperial College London, London, UK., Pullamsetti SS; Max Planck Institute for Heart and Lung Research, Department of Lung Development and Remodeling, Member of the German Center for Lung Research (DZL), Bad Nauheim, Germany.; Department of Internal MedicineUniversities of Giessen and Marburg Lung Center (UGMLC), Member of the DZL, Justus Liebig University, Giessen, Germany., Alzaydi MM; National Heart and Lung Institute, Imperial College London, London, UK.; National Center for Biotechnology, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia., Rhodes CJ; National Heart and Lung Institute, Imperial College London, London, UK., Piva R; Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy., Eichstaedt CA; Centre for Pulmonary Hypertension, Thoraxclinic, Institute for Human Genetics, University of Heidelberg, Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Laboratory of Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Heidelberg, Germany., Grünig E; Centre for Pulmonary Hypertension, Thoraxclinic, Institute for Human Genetics, University of Heidelberg, Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany., Wilkins MR; National Heart and Lung Institute, Imperial College London, London, UK., Wojciak-Stothard B; National Heart and Lung Institute, Imperial College London, London, UK. b.wojciak-stothard@imperial.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2020 Jun 30; Vol. 11 (1), pp. 3300. Date of Electronic Publication: 2020 Jun 30.

Nanoscale tweezers for single-cell biopsies.

Autor: Nadappuram BP; Department of Chemistry, Imperial College London, London, UK., Cadinu P; Department of Chemistry, Imperial College London, London, UK., Barik A; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, USA., Ainscough AJ; Department of Chemistry, Imperial College London, London, UK.; Department of Experimental Medicine and Toxicology, Imperial College London, London, UK., Devine MJ; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK., Kang M; Department of Chemistry, Imperial College London, London, UK., Gonzalez-Garcia J; Department of Chemistry, Imperial College London, London, UK., Kittler JT; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK., Willison KR; Department of Chemistry, Imperial College London, London, UK., Vilar R; Department of Chemistry, Imperial College London, London, UK., Actis P; School of Electronic and Electrical Engineering, Pollard Institute, University of Leeds, Leeds, UK., Wojciak-Stothard B; Department of Experimental Medicine and Toxicology, Imperial College London, London, UK., Oh SH; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, USA., Ivanov AP; Department of Chemistry, Imperial College London, London, UK. alex.ivanov@imperial.ac.uk., Edel JB; Department of Chemistry, Imperial College London, London, UK. joshua.edel@imperial.ac.uk.

Publikováno v: Nature nanotechnology [Nat Nanotechnol] 2019 Jan; Vol. 14 (1), pp. 80-88. Date of Electronic Publication: 2018 Dec 03.