Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ainhoa Sánchez-López"'
Autor:
Víctor Collado-Díaz, Maria Ángeles Martinez-Cuesta, Maria Amparo Blanch-Ruiz, Ainhoa Sánchez-López, Patricia García-Martínez, José E Peris, Iris Usach, Maria Dolores Ivorra, Alessandra Lacetera, Sonsoles Martín-Santamaría, Juan V. Esplugues, Angeles Alvarez
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The cardiovascular toxicity of Abacavir is related to its purinergic structure. Purinergic P2X7-receptors (P2X7R), characterized by activation by high concentrations of ATP and with high plasticity, seem implicated. We appraise the nature of the inte
Externí odkaz:
https://doaj.org/article/b54c2fc280984118ad7cf4027208431e
Autor:
Maria Amparo Blanch‐Ruíz, Ainhoa Sánchez‐López, César Ríos‐Navarro, Raquel Ortega‐Luna, Víctor Collado‐Díaz, Samuel Orden, María Angeles Martínez‐Cuesta, Juan V. Esplugues, Ángeles Álvarez
Publikováno v:
British Journal of Pharmacology. 180:1516-1532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48dc222c58805b6f86cd5f35ba85f0ca
https://doi.org/10.1111/bph.16016
https://doi.org/10.1111/bph.16016
Autor:
Maria Amparo, Blanch-Ruíz, Ainhoa, Sánchez-López, César, Ríos-Navarro, Raquel, Ortega-Luna, Víctor, Collado-Díaz, Samuel, Orden, María Angeles, Martínez-Cuesta, Juan V, Esplugues, Angeles, Alvarez
Publikováno v:
British journal of pharmacology.
Abacavir (ABC) - antiretroviral drug used in HIV-therapy and associated with myocardial infarction - promotes thrombosis through purinergic P2X7R. The role of platelets as pro-thrombotic cells is acknowledged while that of neutrophils - due to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12f414ff407348b7434f5a32b76dab4a
https://pubmed.ncbi.nlm.nih.gov/36541109
https://pubmed.ncbi.nlm.nih.gov/36541109
Autor:
Ainhoa Sánchez-López, Raquel Ortega-Luna, M. A. Martínez-Cuesta, Ángeles Álvarez, María Amparo Blanch-Ruiz
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8454, p 8454 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 8454, p 8454 (2020)
The P2X7 receptor (P2X7R) possesses a unique structure associated to an as yet not fully understood mechanism of action that facilitates cell permeability to large ionic molecules through the receptor itself and/or nearby membrane proteins. High extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c01d11cc647b030f4e1ae4cc6512efc
https://doi.org/10.3390/ijms21228454
https://doi.org/10.3390/ijms21228454
Autor:
Isabel Andújar, María Amparo Blanch-Ruiz, Samuel Orden, Juan V. Esplugues, M. A. Martínez-Cuesta, Ángeles Álvarez, Ana Blas-Garcia, Ainhoa Sánchez-López, Victor Collado-Diaz
Publikováno v:
The Journal of infectious diseases. 218(2)
Background The purinergic system is known to underlie prothrombotic and proinflammatory vascular programs, making the profile of experimental actions demonstrated by abacavir compatible with thrombogenesis. However, direct evidence of a prothrombotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f298741e0c12fdd85704c85770c3292
https://pubmed.ncbi.nlm.nih.gov/29346575
https://pubmed.ncbi.nlm.nih.gov/29346575
Autor:
Alejandro Álvaro-Meca, María A. Jiménez-Sousa, Dariela Micheloud, Ainhoa Sánchez-Lopez, María Heredia-Rodríguez, Eduardo Tamayo, Salvador Resino, on behalf of the Group of Biomedical Research in Critical Care Medicine (BioCritic)
Publikováno v:
Population Health Metrics, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Sepsis has represented a substantial health care and economic burden worldwide during the previous several decades. Our aim was to analyze the epidemiological trends of hospital admissions, deaths, hospital resource expenditures,
Externí odkaz:
https://doaj.org/article/b8c471315f994dfeaf8d481e2692f527