Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ainhoa Arbués"'
Autor:
Hellen Hiza, Michaela Zwyer, Jerry Hella, Ainhoa Arbués, Mohamed Sasamalo, Sonia Borrell, Zhi Ming Xu, Amanda Ross, Daniela Brites, Jacques Fellay, Klaus Reither, Sébastien Gagneux, Damien Portevin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this
Externí odkaz:
https://doaj.org/article/8b12710901d645ebb56de03bec491002
Autor:
Hellen Hiza, Jerry Hella, Ainhoa Arbués, Beatrice Magani, Mohamed Sasamalo, Sebastien Gagneux, Klaus Reither, Damien Portevin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract CD4 T cell phenotyping-based blood assays have the potential to meet WHO target product profiles (TPP) of non-sputum-biomarker-based tests to diagnose tuberculosis (TB). Yet, substantial refinements are required to allow their implementation
Externí odkaz:
https://doaj.org/article/04efe1c3328540c29aa3a11fea40f034
Autor:
Hellen Hiza, Jerry Hella, Ainhoa Arbués, Mohamed Sasamalo, Veronica Misana, Jacques Fellay, Sébastien Gagneux, Klaus Reither, Damien Portevin
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, their modulation may be used to assess antibiotic t
Externí odkaz:
https://doaj.org/article/29c22cb010bb4c4a9ef4bd8f4e67f9cd
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Several in vitro cellular models have been developed with the aim to reproduce and dissect human granulomatous responses, the hallmark of tuberculosis (TB) immunopathogenesis. In that context, we compared two- (2D) versus three-dimensional (3D) granu
Externí odkaz:
https://doaj.org/article/b556ae6d4c984394a3b3c29e0c3059f9
Publikováno v:
Bio-Protocol, Vol 10, Iss 22 (2020)
Granulomas are organized multicellular structures that constitute the hallmark of an infection by the human pathogen Mycobacterium tuberculosis (Mtb). A better understanding of the complex host-Mtb interactions within the granuloma’s environment ma
Externí odkaz:
https://doaj.org/article/48cbfedba9e94d538e890b6bf6cc8cf7
Autor:
Irene Pérez, Santiago Uranga, Fadel Sayes, Wafa Frigui, Sofía Samper, Ainhoa Arbués, Nacho Aguiló, Roland Brosch, Carlos Martín, Jesús Gonzalo-Asensio
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Background: Human tuberculosis (TB) is caused by a plethora of Mycobacterium tuberculosis complex (MTBC) strains belonging to seven phylogenetic branches. Lineages 2, 3 and 4 are considered “modern” branches of the MTBC responsible for the majori
Externí odkaz:
https://doaj.org/article/ad2a78e067c8439d9387b50429cbef1c
Autor:
Ainhoa Arbués, Dominique Brees, Salah-Dine Chibout, Todd Fox, Michael Kammüller, Damien Portevin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008312 (2020)
TNF-α- as well as non-TNF-α-targeting biologics are prescribed to treat a variety of immune-mediated inflammatory disorders. The well-documented risk of tuberculosis progression associated with anti-TNF-α treatment highlighted the central role of
Externí odkaz:
https://doaj.org/article/62a290a796854623a301534dcf5074b8
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22178 (2011)
Under the perspectives of network science and systems biology, the characterization of transcriptional regulatory (TR) networks beyond the context of model organisms offers a versatile tool whose potential remains yet mainly unexplored. In this work,
Externí odkaz:
https://doaj.org/article/75adfa83ab1c4ce6ac531eb670fa5ac3
Autor:
Hellen Hiza, Jerry Hella, Ainhoa Arbués, Mohamed Sasamalo, Veronica Misana, Jacques Fellay, Sébastien Gagneux, Klaus Reither, Damien Portevin
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, their modulation may be used to assess antibiotic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f2b2c0e813a8208bc52caaf1b8ad91
https://doi.org/10.1101/2022.01.26.22269875
https://doi.org/10.1101/2022.01.26.22269875
Autor:
Hellen, Hiza, Jerry, Hella, Ainhoa, Arbués, Mohamed, Sasamalo, Veronica, Misana, Jacques, Fellay, Sébastien, Gagneux, Klaus, Reither, Damien, Portevin
Publikováno v:
Frontiers in medicine. 9
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by