Výsledky vyhledávání - "Ainara Rodríguez Marco"

Akademický článek

Dupilumab Treatment Leads to Rapid and Consistent Improvement of Atopic Dermatitis in All Anatomical Regions in Patients Aged 6 Months to 5 Years

Autor: Elaine C. Siegfried, Eric L. Simpson, Michael J. Cork, Peter D. Arkwright, Lara Wine Lee, Zhen Chen, Randy Prescilla, Ashish Bansal, Noah A. Levit, Ainara Rodríguez Marco

Publikováno v: Dermatology and Therapy, Vol 13, Iss 9, Pp 1987-2000 (2023)

Abstract Introduction Atopic dermatitis (AD) is heterogeneous in distribution pattern and clinical features. This analysis assessed the effect of dupilumab on the extent and severity of AD across various signs (erythema, edema/papulation, excoriation

Externí odkaz: https://doaj.org/article/7f9dd1149078422ab5b7d8705d2ca580

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Efficacy and Safety of Dupilumab Maintained in Adults ≥ 60 Years of Age with Moderate-to-Severe Atopic Dermatitis: Analysis of Pooled Data from Four Randomized Clinical Trials

Autor: Jonathan I. Silverberg, Charles W. Lynde, Katrina Abuabara, Cataldo Patruno, Anna de Benedetto, Haixin Zhang, Ryan B. Thomas, Gaëlle Bégo-Le-Bagousse, Faisal A. Khokhar, Jignesh Vakil, Ainara Rodríguez Marco, Noah A. Levit

Publikováno v: American journal of clinical dermatology, vol 24, iss 3

BackgroundAdults aged ≥ 60 years are often underrepresented in atopic dermatitis (AD) clinical trials; age-related comorbidities may impact treatment efficacy and safety.ObjectiveThe aim was to report dupilumab efficacy and safety in patients aged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3653e11adea55a5677cfba6aee2cdc2
https://escholarship.org/uc/item/6dq7x83r

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340 Dupilumab treatment of children with moderate-to-severe atopic dermatitis increases bone alkaline phosphatase, a marker of bone mineralization

Autor: Alan D Irvine, Amy S Paller, Sara Hamon, Julie Horowitz, Annamaria Farrell, Sarah Hatsell, Ainara Rodríguez Marco, Ashish Bansal, Zhen Chen, Sonya L Cyr

Publikováno v: British Journal of Dermatology. 188

Children with atopic dermatitis (AD) are at risk for low bone mineral density (BMD), which is associated with an increased prevalence of osteopenia, osteoporosis, and fracture risk.1,2 Factors such as restricted nutrition, vitamin D deficiency, poor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd003a47f56f4400338754955e99ca5e
https://doi.org/10.1093/bjd/ljac140.034

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No Increased Risk of Overall Infection in Adults with Moderate-to-Severe Atopic Dermatitis Treated for up to 4 Years with Dupilumab

Autor: Andrew Blauvelt, Andreas Wollenberg, Lawrence F. Eichenfield, Haixin Zhang, Debra Sierka, Faisal A. Khokhar, Jignesh Vakil, Arsalan Shabbir, Ainara Rodríguez Marco, Sonya L. Cyr

Publikováno v: Advances in therapy.

Patients with atopic dermatitis (AD) have an increased risk for infections. This open-label extension study, LIBERTY AD OLE, reports the incidence of infections in adults with moderate-to-severe AD treated with dupilumab for up to 4 years.We evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39b1cbd03d0501006a37fafa97c1f75
https://pubmed.ncbi.nlm.nih.gov/36318387

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Akademický článek

Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundDevelopment of anti-drug antibodies (ADAs) and neutralizing antibodies (NAbs) to monoclonal antibodies may adversely impact pharmacokinetics, efficacy, and/or safety.ObjectiveTo describe incidence, titer, and persistence of dupilumab ADAs a

Externí odkaz: https://doaj.org/article/261ac4e1c27146febf714be3ad3c22c4

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Akademický článek

Gene silencing of SOCS3 by siRNA intranasal delivery inhibits asthma phenotype in mice.

Autor: Ma Paz Zafra, Carla Mazzeo, Cristina Gámez, Ainara Rodriguez Marco, Ana de Zulueta, Veronica Sanz, Izaskun Bilbao, Jesús Ruiz-Cabello, Jose M Zubeldia, Victoria del Pozo

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e91996 (2014)

Suppresors of cytokine signaling (SOCS) proteins regulate cytokine responses and control immune balance. Several studies have confirmed that SOCS3 is increased in asthmatic patients, and SOCS3 expression is correlated with disease severity. The objec

Externí odkaz: https://doaj.org/article/513f06e7d0614026964c286965f5ff13

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