Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Ainara Castellanos–Rubio"'
Autor:
Aina Lluch, Jèssica Latorre, Núria Oliveras-Cañellas, Ana Fernández-Sánchez, José M. Moreno-Navarrete, Anna Castells-Nobau, Ferran Comas, Maria Buxò, José I. Rodríguez-Hermosa, María Ballester, Isabel Espadas, Alejandro Martín-Montalvo, Birong Zhang, You Zhou, Ralph Burkhardt, Marcus Höring, Gerhard Liebisch, Ainara Castellanos-Rubio, Izortze Santin, Asha Kar, Markku Laakso, Päivi Pajukanta, Vesa M. Olkkonen, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102040- (2024)
Background: Long non-coding RNAs (lncRNAs) can perform tasks of key relevance in fat cells, contributing, when defective, to the burden of obesity and its sequelae. Here, scrutiny of adipose tissue transcriptomes before and after bariatric surgery (G
Externí odkaz:
https://doaj.org/article/ca620d31a1364335831107541b0e2f56
Autor:
Ane Olazagoitia‐Garmendia, Henar Rojas‐Márquez, Maialen Sebastian‐delaCruz, Aloña Agirre‐Lizaso, Anne Ochoa, Luis Manuel Mendoza‐Gomez, Maria J Perugorria, Luis Bujanda, Alain Huerta Madrigal, Izortze Santin, Ainara Castellanos‐Rubio
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Cytokine mediated sustained inflammation increases the risk to develop different complex chronic inflammatory diseases, but the implicated mechanisms remain unclear. Increasing evidence shows that long noncoding RNAs (lncRNAs) play key roles
Externí odkaz:
https://doaj.org/article/2f41a2bb7e6d45ddbe55bfb28e891916
Autor:
Henar Rojas-Márquez, Ane Olazagoitia-Garmendia, Maria Jesus Perugorria, Alain Huerta, Luis Bujanda, Ainara Castellanos-Rubio
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 8, Pp 1132-1134 (2024)
Externí odkaz:
https://doaj.org/article/c4aa1475fffe43f6b3e582ba6f3cdde2
Autor:
Ane Olazagoitia-Garmendia, Rodrigo Senovilla-Ganzo, Fernando García-Moreno, Ainara Castellanos-Rubio
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Long noncoding RNAs have been identified in most vertebrates, but the functional characterization of these molecules is challenging, mainly due to the lack of linear sequence homology between species. In this work, we aimed to find functiona
Externí odkaz:
https://doaj.org/article/6f6db5c05af94e479657ba32adff3bad
Autor:
Itziar González-Moro, Henar Rojas-Márquez, Maialen Sebastian-delaCruz, Jon Mentxaka-Salgado, Ane Olazagoitia-Garmendia, Luis Manuel Mendoza, Aina Lluch, Federica Fantuzzi, Carmen Lambert, Jessica Ares Blanco, Lorella Marselli, Piero Marchetti, Miriam Cnop, Elías Delgado, José Manuel Fernández-Real, Francisco José Ortega, Ainara Castellanos-Rubio, Izortze Santin
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionMost of the disease-associated single nucleotide polymorphisms (SNPs) lie in non- coding regions of the human genome. Many of these variants have been predicted to impact the expression and function of long non-coding RNAs (lncRNA), but t
Externí odkaz:
https://doaj.org/article/ebe17607831f49a7867679d95c1d4143
Autor:
Nora Fernandez-Jimenez, Koldo Garcia-Etxebarria, Leticia Plaza-Izurieta, Irati Romero-Garmendia, Amaia Jauregi-Miguel, Maria Legarda, Szilvia Ecsedi, Ainara Castellanos-Rubio, Vincent Cahais, Cyrille Cuenin, Davide Degli Esposti, Iñaki Irastorza, Hector Hernandez-Vargas, Zdenko Herceg, Jose Ramon Bilbao
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD could be driven by oth
Externí odkaz:
https://doaj.org/article/49108c83776145ee885324a210722b7d
Autor:
Amaia Jauregi-Miguel, Izortze Santin, Koldo Garcia-Etxebarria, Ane Olazagoitia-Garmendia, Irati Romero-Garmendia, Maialen Sebastian-delaCruz, Iñaki Irastorza, Spanish Consortium for the Genetics of Celiac Disease, Ainara Castellanos-Rubio, Jose Ramón Bilbao
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Celiac disease (CD) patients present a loss of intestinal barrier function due to structural alterations in the tight junction (TJ) network, the most apical unions between epithelial cells. The association of TJ-related gene variants points to an imp
Externí odkaz:
https://doaj.org/article/59193204e3404c659d3ab3fdb52d1104
Autor:
Ainara Castellanos-Rubio, Sankar Ghosh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Immune-mediated diseases, such as celiac disease, type 1 diabetes or multiple sclerosis, are a clinically heterogeneous group of diseases that share many key genetic triggers. Although the pathogenic mechanisms responsible for the development of immu
Externí odkaz:
https://doaj.org/article/f7e50b9a0fcc48f3b7f260728e0f6840
Autor:
Maialen Sebastian-delaCruz, Itziar Gonzalez-Moro, Ane Olazagoitia-Garmendia, Ainara Castellanos-Rubio, Izortze Santin
Publikováno v:
Non-Coding RNA, Vol 7, Iss 1, p 3 (2021)
mRNA stability influences gene expression and translation in almost all living organisms, and the levels of mRNA molecules in the cell are determined by a balance between production and decay. Maintaining an accurate balance is crucial for the correc
Externí odkaz:
https://doaj.org/article/40ee4a585dfc42bfaa83552da6dc5a2b
Autor:
Maialen Sebastian-delaCruz, Ane Olazagoitia-Garmendia, Itziar Gonzalez-Moro, Izortze Santin, Koldo Garcia-Etxebarria, Ainara Castellanos-Rubio
Publikováno v:
Epigenomes, Vol 4, Iss 3, p 16 (2020)
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract that develops due to the interaction between genetic and environmental factors. More than 160 loci have been associated with IBD, but the functional im
Externí odkaz:
https://doaj.org/article/4e7460e68bb64b5fb984cc8a10dc1610