Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aina Zurita Martinez"'
Autor:
Gad Getz, Eugen Tausch, Matthew S. Davids, Stacey M. Fernandes, Jennifer R. Brown, Aina Zurita Martinez, Neil E. Kay, Florence Cymbalista, Laxmi Parida, Filippo Utro, William G. Wierda, Sameer A. Parikh, Christof Schneider, Kahn Rhrissorrakrai, Bria Persaud, Stephan Stilgenbauer, Nitin Jain, Donna Neuberg, Julien Broséus, Chaya Levovitz, Daniel Rosebrock, Liudmila Elagina, Annabelle J. Anandappa, Camilla Koldbæk Lemvigh, Romain Guieze, Ignaty Leshchiner, Amaro Taylor-Weiner, Thomas J. Kipps, Erin M. Parry, Brian P. Danysh, Teddy Huang, Kara Slowik, Kenneth J. Livak, Johannes Bloehdorn, Noelia Purroy, Catherine J. Wu, Laura Z. Rassenti, Shuqiang Li
Publikováno v:
Blood. 136:47-48
Richter's syndrome (RS) arising from chronic lymphocytic leukemia (CLL) is a striking example of an aggressive malignant histology that emerges from indolent cancer. A major barrier to disease control in CLL, RS is associated with poor clinical outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c5fb3747d6ed77bf6bb602f73f481d2
https://doi.org/10.1182/blood-2020-139456
https://doi.org/10.1182/blood-2020-139456
Autor:
Adrian Wiestner, Fara Faye Regis, Lili Wang, Jing Sun, Esther A. Obeng, Rutendo Gambe, Jean Fan, Shanye Yin, Angela N. Brooks, Amaro Taylor-Weiner, Emanuela M. Ghia, Carrie Cibulskis, Robin Reed, Thomas J. Kipps, Donna Neuberg, Ignaty Leshchiner, Ruben D. Carrasco, Mark D. Fleming, Zachary J. Cartun, James A. DeCaprio, Benjamin L. Ebert, Youzhong Wan, Elisa Ten Hacken, Sarah E. M. Herman, Catherine J. Wu, Laura Z. Rassenti, Gad Getz, Aina Zurita Martinez, Dean R. Campagna
Publikováno v:
Cancer cell, vol 35, iss 2
SF3B1 is recurrently mutated in chronic lymphocytic leukemia (CLL), but its role in the pathogenesis of CLL remain elusive. Here, we show that conditional expression of Sf3b1-K700E mutation in mouse B cells disrupts pre-mRNA splicing, alters cell dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a552fc6456f9a24e7ec4a5a8d172d93c
https://escholarship.org/uc/item/101965h5
https://escholarship.org/uc/item/101965h5
Autor:
Justin F. Gainor, James W. Rocco, Sai-Hong Ignatius Ou, Aina Zurita Martinez, Mari Mino-Kenudson, Marguerite Rooney, Alice T. Shaw, Mroz E, Catherine J. Wu, Daniel Rosebrock, Jaegil Kim, J. A. Engelman, Dimitri Livitz, Jiachen Lin, Ignaty Leshchiner, Oliver Spiro, Liudmila Elagina, Ivana Bozic, Chip Stewart, Gad Getz
Driver mutations alter cells from normal to cancer through several evolutionary epochs: premalignancy, early malignancy, subclonal diversification, metastasis and resistance to therapy. Later stages of disease can be explored through analyzing multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8acc1be28e99b1eb24bd785ac08e68
Autor:
Aina Zurita Martinez, Donna Neuberg, William G. Wierda, Lars Rønn Olsen, Gad Getz, Nitin Jain, Peter V. Kharchenko, Shuqiang Li, Kenneth Livak, Ana Lako, Scott J. Rodig, Catherine J. Wu, Camilla Koldbæk Lemvigh, Ignaty Leshchiner, Giacomo Oliveira, Erin M. Parry, Lillian Werner, Annabelle J. Anandappa, Pavan Bachireddy, Noelia Purroy, Satyen H. Gohil, Teddy Huang
Publikováno v:
Blood. 134:680-680
Despite advances in the treatment of chronic lymphocytic leukemia (CLL), the transformation of CLL to an aggressive lymphoma, or Richter's transformation (RT), remains a clinical challenge, as it responds poorly to standard therapies and shortens sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09d288c6c636e6d212b4e1bda6f964be
https://doi.org/10.1182/blood-2019-125904
https://doi.org/10.1182/blood-2019-125904
Autor:
Adrian Wiestner, Delong Liu, Clare Sun, Daniel Rosebrock, Yun-Ching Chen, Gad Getz, Mehdi Pirooznia, Aina Zurita Martinez, Catherine J. Wu
Publikováno v:
Blood. 134:3017-3017
Activation and proliferation of chronic lymphocytic leukemia (CLL) cells depend on signals from the lymph node (LN) tumor microenvironment (TME). Separately, the genetic makeup of CLL has been closely linked to disease aggressiveness and its capacity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d32ea219c7300e5f209592e1f26e961
https://doi.org/10.1182/blood-2019-123441
https://doi.org/10.1182/blood-2019-123441
Autor:
Vamsi K. Mootha, John G. Doench, Shuqiang Li, Alexis Jourdain, Aina Zurita Martinez, Giulia Notarangelo, Matthew S. Davids, Cory M. Johannessen, María Hernández-Sánchez, Romain Guieze, Philip A. Thompson, Zacchary Cartun, Kaitlyn Baranowski, Ozan Aygün, Sun Jing, Wade Harper, Catherine J. Wu, Donna Neuberg, Heo Jin-Mi, Steven A. Carr, Ignaty Leshchiner, Federica Piccioni, Daniel Rosebrock, Vivian M. Liu, Jennifer R. Brown, Dimitri Livitz, Christopher J. Ott, Gad Getz, William G. Wierda, Anthony Letai
Publikováno v:
Blood. 132:893-893
The FDA-approval of potent targeted therapies has led to great changes in the therapeutic landscape of chronic lymphocytic leukemia (CLL). As a key example, venetoclax, a first-in-class BCL-2 inhibitor, leads to response in about 80% of patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ded7c5d267496683740c598a9ad0618
https://doi.org/10.1182/blood-2018-99-118604
https://doi.org/10.1182/blood-2018-99-118604
Autor:
Ruben D. Carrasco, Shanye Yin, Adrian Wiestner, Lili Wang, Mark D. Fleming, Aina Zurita Martinez, Dean R. Campagna, Fara Faye Regis, Ignaty Leshchiner, Gad Getz, Benjamin L. Ebert, Sarah E. M. Herman, Elisa Ten Hacken, Esther A. Obeng, Angela N. Brooks, Catherine J. Wu
Publikováno v:
Blood. 132:947-947
Collective large-scale sequencing efforts have unexpectedly revealed the high frequency of mutations in the splicing factor genes (SF3B1, U2AF1, SRSF2, ZRSR2) in various solid and hematological cancers, suggesting the association of splicing dysregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeea2845dd2a0c8d6c2709e1e1ed7fc8
https://doi.org/10.1182/blood-2018-99-117691
https://doi.org/10.1182/blood-2018-99-117691
Publikováno v:
Revista Española de Cirugía Oral y Maxilofacial v.29 n.6 2007
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
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SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774d379ca7190f12f0af7617252addc7
https://doi.org/10.4321/s1130-05582007000600008
https://doi.org/10.4321/s1130-05582007000600008