Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Aina Westrheim Ravna"'
Autor:
Adrina Kalasho Kuzmiszyn, Anders Lund Selli, Natalia Smaglyukova, Timofei Kondratiev, Ole-Martin Fuskevåg, Roy Andre Lyså, Aina Westrheim Ravna, Torkjel Tveita, Georg Sager, Erik Sveberg Dietrichs
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Introduction: Rewarming from accidental hypothermia is often complicated by hypothermia-induced cardiovascular dysfunction, which could lead to shock. Current guidelines do not recommend any pharmacological treatment at core temperatures below 30°C,
Externí odkaz:
https://doaj.org/article/218ba614aef944caa6c5b774dba33ce7
Autor:
Aina Westrheim Ravna, Sondre Ulstein Odland, Georg Sager, Erik Sveberg Dietrichs, Natalia Smaglyukova
The biodynamics and biokinetics of sex hormones are complex. In addition to the classical steroid receptors (nuclear receptors), these hormones act through several non-genomic mechanisms. Modulation of ABC-transporters by progesterone represents a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f222463944499df04f4d813683fb0a4
https://hdl.handle.net/10037/23293
https://hdl.handle.net/10037/23293
Publikováno v:
Bioorganicmedicinal chemistry. 36
The dominant sex hormone testosterone is mainly metabolized by liver enzymes belonging to the uridine-diphospho (UDP) glucuronosyltransferase (UGT) family. These enzymes are the main phase II enzymes, and they have an important role in the detoxifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c19b280bd6397fa22424f1ca4accbef
https://pubmed.ncbi.nlm.nih.gov/33691270
https://pubmed.ncbi.nlm.nih.gov/33691270
Autor:
Farzane Kuresh Kashgari, Erik Sveberg Dietrichs, Georg Sager, Istvan J. Enyedy, Aina Westrheim Ravna, Roy Andre Lyså
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss, Pp 110109-(2020)
Background - Clinical studies have reported overexpression of PDE5 and elevation of intracellular cyclic GMP in various types of cancer cells. ABCC5 transports cGMP out of the cells with high affinity. PDE5 inhibitors prevent both cellular metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c334d1efadc6b2fbc198eb47cbaf3d
https://hdl.handle.net/10037/20662
https://hdl.handle.net/10037/20662
Publikováno v:
Future Medicinal Chemistry. 10:135-155
Aim: Low oxytocin (OT) level is involved in a number of psychiatric diseases, indicating that OT could be used to aid treating these disorders. OT itself is unable to cross the blood–brain barrier, and development of new small nonpeptide drugs targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9cd52c41088b2d3a47336bd990ea42
https://doi.org/10.4155/fmc-2017-0078
https://doi.org/10.4155/fmc-2017-0078
Autor:
Aina Westrheim Ravna
Publikováno v:
Aktuel Nordisk Odontologi. 42:121-129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c2a174baa00e5be573ada51c972bae
https://doi.org/10.18261/issn.2058-7538-2016-01-11
https://doi.org/10.18261/issn.2058-7538-2016-01-11
Autor:
Georg Sager, Roy A. Lysaa, Anna Subbotina, Ryszard Bugno, Aina Westrheim Ravna, Ruben Abagyan
Publikováno v:
The Journal of pharmacy and pharmacology, vol 69, iss 6
The Journal of Pharmacy and Pharmacology
The Journal of Pharmacy and Pharmacology
This is the final version of the following article: Subbotina, A., Ravna, A.W., Lyså, R.A., Abagyan, R., Bugno, R. & Sager, G. (2017). Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbe2530316866e1adcef5dd35f38fc6
https://escholarship.org/uc/item/6gd50420
https://escholarship.org/uc/item/6gd50420
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 3, Pp 4878-4902 (2014)
International Journal of Molecular Sciences
Volume 15
Issue 3
Pages 4878-4902
International Journal of Molecular Sciences
Volume 15
Issue 3
Pages 4878-4902
The mitogen-activated protein kinase-activated protein kinase MK5 is a substrate of the mitogen-activated protein kinases p38, ERK3 and ERK4. Cell culture and animal studies have demonstrated that MK5 is involved in tumour suppression and promotion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb3bb9ec72e14c733632b423e27f2b5
http://www.mdpi.com/1422-0067/15/3/4878
http://www.mdpi.com/1422-0067/15/3/4878
Publikováno v:
Pharmacology & Pharmacy. :104-109
In the present study we have characterized ATP-dependent transport of cAMP and cGMP in physiological, but also supraphysiological concentrations. The uptake into inside-out vesicles from human erythrocytes could be dissected into two components with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c3631e24f50987a8eaf653047dfd2d
https://doi.org/10.4236/pp.2013.41015
https://doi.org/10.4236/pp.2013.41015
Autor:
Ingebrigt Sylte, Zdzisław Chilmonczyk, Rafał Kurczab, Aina Westrheim Ravna, Mari Gabrielsen, Andrzej J. Bojarski, Ruben Abagyan, Irina Kufareva
Publikováno v:
European Journal of Medicinal Chemistry. 47:24-37
The two main groups of antidepressant drugs, the tricyclic antidepressants (TCAs) and the selective serotonin reuptake inhibitors (SSRIs), as well as several other compounds, act by inhibiting the serotonin transporter (SERT). However, the binding mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3f75bd4063051d4bd49b26526dd1a2
https://doi.org/10.1016/j.ejmech.2011.09.056
https://doi.org/10.1016/j.ejmech.2011.09.056