Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Aimy, Sebastian"'
Autor:
Chandrakumar Bogguri, Vivek Kurien George, Beheshta Amiri, Alexander Ladd, Nicholas R. Hum, Aimy Sebastian, Heather A. Enright, Carlos A. Valdez, T. Nathan Mundhenk, Jose Cadena, Doris Lam
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Organophosphorus nerve agents (OPNA) are hazardous environmental exposures to the civilian population and have been historically weaponized as chemical warfare agents (CWA). OPNA exposure can lead to several neurological, sensory, and motor symptoms
Externí odkaz:
https://doaj.org/article/2c2b58c2460a469e8a5d95815e53ca1f
Autor:
Candice G. T. Tahimic, Sonette Steczina, Aimy Sebastian, Nicholas R. Hum, Metadel Abegaz, Masahiro Terada, Maria Cimini, David A. Goukassian, Ann-Sofie Schreurs, Tana M. Hoban-Higgins, Charles A. Fuller, Gabriela G. Loots, Ruth K. Globus, Yasaman Shirazi-Fard
Publikováno v:
Genes, Vol 15, Iss 8, p 975 (2024)
Microgravity exposure induces a cephalad fluid shift and an overall reduction in physical activity levels which can lead to cardiovascular deconditioning in the absence of countermeasures. Future spaceflight missions will expose crew to extended peri
Externí odkaz:
https://doaj.org/article/b556bfb69eec4b2dbb9127ad4c3572b7
Autor:
Janna M. Emery, Betsabel Chicana, Hanna Taglinao, Citlaly Ponce, Cristine Donham, Hawa Padmore, Aimy Sebastian, Scott L. Trasti, Jennifer O. Manilay
Publikováno v:
Frontiers in Hematology, Vol 2 (2024)
IntroductionErythropoiesis occurs in a specialized niche in the bone marrow and is regulated in part by oxygen-sensing signaling pathways. VHL is an E3 ubiquitin ligase that regulates the degradation of hypoxia-inducible factor (HIF) proteins under n
Externí odkaz:
https://doaj.org/article/4a49c124cf3840839390f0f8b623b95e
Autor:
Aimy Sebastian, Kelly A. Martin, Ivana Peran, Nicholas R. Hum, Nicole F. Leon, Beheshta Amiri, Stephen P. Wilson, Matthew A. Coleman, Elizabeth K. Wheeler, Stephen W. Byers, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the top five deadliest forms of cancer with very few treatment options. The 5-year survival rate for PDAC is 10% following diagnosis. Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been su
Externí odkaz:
https://doaj.org/article/50a6f40489714f8794e255c10b83ab8d
Autor:
Doris Lam, Aimy Sebastian, Chandrakumar Bogguri, Nicholas R. Hum, Alexander Ladd, Jose Cadena, Carlos A. Valdez, Nicholas O. Fischer, Gabriela G. Loots, Heather A. Enright
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Fentanyl is one of the most common opioid analgesics administered to patients undergoing surgery or for chronic pain management. While the side effects of chronic fentanyl abuse are recognized (e.g., addiction, tolerance, impairment of cognitive func
Externí odkaz:
https://doaj.org/article/e29acf262dd54a4293736846a13d9a09
Autor:
Aimy Sebastian, Nicholas R. Hum, Jillian L. McCool, Stephen P. Wilson, Deepa K. Murugesh, Kelly A. Martin, Naiomy Deliz Rios-Arce, Beheshta Amiri, Blaine A. Christiansen, Gabriela G. Loots
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people world-wide. Accumulating evidence attests to the important roles of the immune system in OA pathogenesis. Understanding the role of various immune cells in joint
Externí odkaz:
https://doaj.org/article/f300656bbb3c4474aac3fe6b2c690ffd
Autor:
Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to lack of targetable receptors and intertumoral heterogeneity, triple negative breast cancer (TNBC) remains particularly difficult to treat. Doxorubicin (DOX) is typically used as nonselective neoadjuvant chemotherapy, but the diversity of treat
Externí odkaz:
https://doaj.org/article/c68fb0a68f6b4394a52c6b409b8dbd81
Autor:
Amit Kumar Rai, K. Shanmugha Rajan, Malik Bisserier, Agnieszka Brojakowska, Aimy Sebastian, Angela C. Evans, Matthew A. Coleman, Paul J. Mills, Arsen Arakelyan, Shizuka Uchida, Lahouaria Hadri, David A. Goukassian, Venkata Naga Srikanth Garikipati
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
During spaceflight, astronauts are exposed to various physiological and psychological stressors that have been associated with adverse health effects. Therefore, there is an unmet need to develop novel diagnostic tools to predict early alterations in
Externí odkaz:
https://doaj.org/article/84d74f0fe1d04e32a3384ed3b4a9b671
Autor:
Malik Bisserier, Agnieszka Brojakowska, Nathaniel Saffran, Amit Kumar Rai, Brooke Lee, Matthew Coleman, Aimy Sebastian, Angela Evans, Paul J. Mills, Sankar Addya, Arsen Arakelyan, Venkata Naga Srikanth Garikipati, Lahouaria Hadri, David A. Goukassian
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
There are unique stressors in the spaceflight environment. Exposure to such stressors may be associated with adverse effects on astronauts' health, including increased cancer and cardiovascular disease risks. Small extracellular vesicles (sEVs, i.e.,
Externí odkaz:
https://doaj.org/article/bbefd550bc9e444082b1c7e3af1d6abf
Autor:
David Goukassian, Arsen Arakelyan, Agnieszka Brojakowska, Malik Bisserier, Siras Hakobyan, Lahouaria Hadri, Amit Kumar Rai, Angela Evans, Aimy Sebastian, May Truongcao, Carolina Gonzalez, Anamika Bajpai, Zhongjian Cheng, Praveen Kumar Dubey, Sankar Addya, Paul Mills, Kenneth Walsh, Raj Kishore, Matt Coleman, Venkata Naga Srikanth Garikipati
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/6e4e59e2685345c8b957e77b67506dfd