Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aimon Alkanani"'
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Type 1 diabetes results from an autoimmune attack directed at pancreatic beta cells predominantly mediated by T cells. Transplantation of stem cell derived beta-like cells (sBC) have been shown to rescue diabetes in preclinical animal models. However
Externí odkaz:
https://doaj.org/article/06fd99859a4448dc9697d80e55dbb658
Autor:
KIMBER SIMMONS, ANGELA M. MITCHELL, AIMON ALKANANI, KRISTEN MCDANIEL, ERIN BASCHAL, TAYLOR ARMSTRONG, LAURA PYLE, LIPING YU, AARON W. MICHELS
Publikováno v:
Diabetes. 69
Human leucocyte antigen (HLA) class II genes confer significant genetic risk for type 1 diabetes (T1D) development and protection. The dominant protection afforded by the DRB1*15:01 (DR15)-DQA1*01:02-DQB1*06:02 (DQ6) haplotype across all stages of T1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd3f5be414548408b05141096dd0e99
https://doi.org/10.2337/db20-252-or
https://doi.org/10.2337/db20-252-or
Autor:
Eddie A, James, Joana R F, Abreu, John W, McGinty, Jared M, Odegard, Yvonne E, Fillié, Claire N, Hocter, Slobodan, Culina, Kristin, Ladell, David A, Price, Aimon, Alkanani, Marynette, Rihanek, Lisa, Fitzgerald-Miller, Ania, Skowera, Cate, Speake, Peter, Gottlieb, Howard W, Davidson, F Susan, Wong, Bart, Roep, Roberto, Mallone
Publikováno v:
Diabetologia. 61(3)
Validated biomarkers are needed to monitor the effects of immune intervention in individuals with type 1 diabetes. Despite their importance, few options exist for monitoring antigen-specific T cells. Previous reports described a combinatorial approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17cc2c815c8cecbb460f585597e01cff
https://pubmed.ncbi.nlm.nih.gov/29196783
https://pubmed.ncbi.nlm.nih.gov/29196783