Zobrazeno 1 - 10
of 986
pro vyhledávání: '"Aimin Xu"'
Autor:
Xiaowen Huang, Pengju Wei, Cheng Fang, Min Yu, Shilun Yang, Linhui Qiu, Yu Wang, Aimin Xu, Ruby Lai Chong Hoo, Junlei Chang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract The blood-brain barrier (BBB) is a critical interface that maintains the central nervous system homeostasis by controlling the exchange of substances between the blood and the brain. Disruption of the BBB plays a vital role in the developmen
Externí odkaz:
https://doaj.org/article/b51dc661b9f841bcb71c732f4338d00d
Autor:
Kelvin Ka-lok Wu, Xiaofan Xu, Manyin Wu, Xiaomu Li, Moinul Hoque, Gloria Hoi Yee Li, Qizhou Lian, Kekao Long, Tongxi Zhou, Hailong Piao, Aimin Xu, Hannah Xiaoyan Hui, Kenneth King-yip Cheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract M1 macrophages induce protective immunity against infection, but also contribute to metabolic and inflammatory diseases. Here we show that the E3 ubiquitin ligase, MDM2, promotes the glycolytic and inflammatory activities of M1 macrophage by
Externí odkaz:
https://doaj.org/article/a3cecd46ad844e0ca36f7a957405e747
Autor:
Jinli Mahe, Ao Xu, Li Liu, Lei Hua, Huiming Tu, Yujia Huo, Weiyuan Huang, Xinru Liu, Jian Wang, Jinhao Tang, Yang Zhao, Zhining Liu, Qiaojun Hong, Rong Ye, Panpan Hu, Peng Jia, Junjie Huang, Xiangyi Kong, Zongyuan Ge, Aimin Xu, Longfei Wu, Chaopin Du, Feng Shi, Hanbin Cui, Shengfeng Wang, Zhihui Li, Liang Wang, Lei Zhang, Lin Zhang
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background It is uncertain whether the weekend warrior pattern is associated with all-cause mortality among adults living with type 2 diabetes. This study explored how the ‘weekend warrior’ physical activity (PA) pattern was associated w
Externí odkaz:
https://doaj.org/article/0728715e63aa460dae4c9dd44d1afa14
Autor:
Jiarui Chen, Ronald Siyi Lu, Candela Diaz-Canestro, Erfei Song, Xi Jia, Yan Liu, Cunchuan Wang, Cynthia K.Y. Cheung, Gianni Panagiotou, Aimin Xu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 791-800 (2024)
Abstracts: Introduction: Metabolic disturbances are major contributors to the onset and progression of non-alcoholic fatty liver disease (NAFLD), which includes a histological spectrum ranging from single steatosis (SS) to non-alcoholic steatohepatit
Externí odkaz:
https://doaj.org/article/8daa620be9e24b74a5135fab902f6fe4
Autor:
Longguo Zhang, Huixin Li, Fangyan Sun, Qiuping Wu, Leigang Jin, Aimin Xu, Jiarui Chen, Ranyao Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDue to the unique heterogeneity of neuroblastoma, its treatment and prognosis are closely related to the biological behavior of the tumor. However, the effect of the tumor immune microenvironment on neuroblastoma needs to be investigated, a
Externí odkaz:
https://doaj.org/article/13cc29a86f174eba877839c6d94a5f6e
Autor:
Lin Liu, Juanying Zhen, Shuyun Liu, Lijie Ren, Guoru Zhao, Jianguo Liang, Aimin Xu, Chao Li, Jun Wu, Bernard Man Yung Cheung
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Irregular sleep patterns have been associated with inflammation. Galectin-3, a novel biomarker, plays an important role in inflammation. We investigated the relationship between sleep patterns and galectin-3 in a Chinese populatio
Externí odkaz:
https://doaj.org/article/06a38d7642124868914b0ad8f8935e01
Autor:
Roy Chun-Laam Ng, Min Jian, Oscar Ka-Fai Ma, Ariya Weiman Xiang, Myriam Bunting, Jason Shing-Cheong Kwan, Curtis Wai-Kin Wong, Leung-Wah Yick, Sookja Kim Chung, Karen Siu-Ling Lam, Ian E. Alexander, Aimin Xu, Koon-Ho Chan
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Adiponectin (APN) is an adipokine which predominantly expresses in adipocytes with neuroprotective and anti-inflammatory effects. We have recently indicated that circulatory trimeric APN can enter the brain by crossing the blood–brain barr
Externí odkaz:
https://doaj.org/article/6eb49e54f24241c98ba0ec6dd4b65832
Autor:
Yao Wang, Jiarui Chen, Yueqiong Ni, Yan Liu, Xiang Gao, Michael Andrew Tse, Gianni Panagiotou, Aimin Xu
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Background The importance of gut microbes in mediating the benefits of lifestyle intervention is increasingly recognized. However, compared to the bacterial microbiome, the role of intestinal fungi in exercise remains elusive. With our established ra
Externí odkaz:
https://doaj.org/article/1087ce547a31400ea5ba09a61cf39aab
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
ABSTRACTHeart failure, a leading driver of global mortality, remains a topic of intense contemporary research interest due to the prevailing unmet need in cardiometabolic therapeutics. Numerous mechanisms with the potential to influence the onset and
Externí odkaz:
https://doaj.org/article/7924a5ec7a0b46bf9182d15a49b41aa3
Autor:
Xiaoping Wu, Lai Yee Cheong, Lufengzi Yuan, Leigang Jin, Zixuan Zhang, Yang Xiao, Zhiguang Zhou, Aimin Xu, Ruby LC Hoo, Lingling Shu
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Type 1 diabetes (T1D) is a chronic disease characterized by self‐destruction of insulin‐producing pancreatic β cells by cytotoxic T cell activity. However, the pathogenic mechanism of T cell infiltration remains obscure. Recently, tissu
Externí odkaz:
https://doaj.org/article/2d1d40e92cea4a5db59baec244a2bdc8