Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Aimin Peng"'
Publikováno v:
eLife, Vol 12 (2023)
Checkpoint activation after DNA damage causes a transient cell cycle arrest by suppressing cyclin-dependent kinases (CDKs). However, it remains largely elusive how cell cycle recovery is initiated after DNA damage. In this study, we discovered the up
Externí odkaz:
https://doaj.org/article/e7c8d92f3a0240069476c4fb4ddf4258
Publikováno v:
Atmosphere, Vol 14, Iss 10, p 1548 (2023)
Urumqi City, located in the northwest of China, is a city with a high indoor radon concentration in a nationwide indoor radon survey in China. This study focuses on the assessment of the indoor radon level and its distribution in this city. Indoor ra
Externí odkaz:
https://doaj.org/article/c0f923ea8259423cb16b82fa3c1f8524
Autor:
Odjo G. Gouttia, Jing Zhao, Yanqiu Li, Mackenzie J. Zwiener, Ling Wang, Gregory G. Oakley, Aimin Peng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Platinum-based chemotherapy is the standard first-line treatment for oral squamous cell carcinoma (OSCC) that is inoperable, recurrent, or metastatic. Platinum sensitivity is a major determinant of patient survival in advanced OSCC. Here, we investig
Externí odkaz:
https://doaj.org/article/68f5aba1ff7448eaa9c2d20ee62a81ee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
First-line treatments for oral cancer typically include surgery, radiation, and in some cases, chemotherapy. Radiation and oral cancer chemotherapeutics confer cytotoxicity largely by inducing DNA damage, underscoring the importance of the cellular D
Externí odkaz:
https://doaj.org/article/54db90cd8242474dbffeb650c6d74b5e
Autor:
Songli Zhu, Mohammadjavad Paydar, Feifei Wang, Yanqiu Li, Ling Wang, Benoit Barrette, Tadayoshi Bessho, Benjamin H Kwok, Aimin Peng
Publikováno v:
eLife, Vol 9 (2020)
DNA double strand breaks (DSBs) have detrimental effects on cell survival and genomic stability, and are related to cancer and other human diseases. In this study, we identified microtubule-depolymerizing kinesin Kif2C as a protein associated with DS
Externí odkaz:
https://doaj.org/article/335398a307dd48f6895ff3abe516284a
Mitotic progression is regulated largely by reversible phosphorylation events that are mediated by mitotic kinases and phosphatases. Protein phosphatase 1 (PP1) has been shown to play a crucial role in regulation of mitotic entry, progression, and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1175c36a46ff3c230405a6a3a636a13e
https://doi.org/10.1158/1541-7786.c.6541032.v1
https://doi.org/10.1158/1541-7786.c.6541032.v1
S1. PNUTS knockdown reduced mitotic phosphorylation of Aurora B.1. PNUTS knockdown reduced mitotic phosphorylation of Aurora B. S2. The subcellular localization of PNUTS. S3. PNUTS targeting renders cancer cells sensitive to Aurora inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a60ccb01fa1f44b65a06baee11730b5
https://doi.org/10.1158/1541-7786.22515309.v1
https://doi.org/10.1158/1541-7786.22515309.v1
Autor:
Aimin Peng, Li Lan, James K. Wahl, Nicholas J. Eurek, Ling Wang, Laura A. Fisher, Songli Zhu, Feifei Wang
Figure S1. PNUTS depletion causes endogenous DNA damage. Figure S2. PNUTS depletion leads to DNA damage hypersensitivity. Figure S3. The recruitment of PNUTS to DNA damage sites is dependent on PARP1. Figure S4. PNUTS is required for the efficient in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da3a800f6efaa585668c7880c6fd2d9
https://doi.org/10.1158/0008-5472.22418430
https://doi.org/10.1158/0008-5472.22418430
Autor:
Aimin Peng, Li Lan, James K. Wahl, Nicholas J. Eurek, Ling Wang, Laura A. Fisher, Songli Zhu, Feifei Wang
Movie S1. The recruitment of GFP-PNUTS after laser microirradiation is shown in a 10 min period.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934281d4200136dd999aa2b39eb5bcc9
https://doi.org/10.1158/0008-5472.22418427
https://doi.org/10.1158/0008-5472.22418427