Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aimee Sekine"'
Autor:
Richard Green, Courtney Wilkins, Sunil Thomas, Aimee Sekine, Duncan M. Hendrick, Kathleen Voss, Renee C. Ireton, Michael Mooney, Jennifer T. Go, Gabrielle Choonoo, Sophia Jeng, Fernando Pardo-Manuel de Villena, Martin T. Ferris, Shannon McWeeney, Michael Gale Jr.
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1665-1682 (2017)
The oligoadenylate-synthetase (Oas) gene locus provides innate immune resistance to virus infection. In mouse models, variation in the Oas1b gene influences host susceptibility to flavivirus infection. However, the impact of Oas variation on overall
Externí odkaz:
https://doaj.org/article/c6099d1249e74e98b97acf3c32b3548a
Autor:
Richard Green, Courtney Wilkins, Sunil Thomas, Aimee Sekine, Renee C. Ireton, Martin T. Ferris, Duncan M. Hendrick, Kathleen Voss, Fernando Pardo-Manuel de Villena, Ralph S. Baric, Mark T. Heise, Michael Gale Jr.
Publikováno v:
Genomics Data, Vol 10, Iss C, Pp 137-140 (2016)
West Nile Virus (WNV) is a mosquito-transmitted virus from the Flaviviridae family that causes fever in 1 in 5 infected people. WNV can also become neuro-invasive and cross the blood-brain barrier leading to severe neurological symptoms in a subset o
Externí odkaz:
https://doaj.org/article/a399edad7fcb4b8696afd8f4af0a5968
Autor:
Richard Green, Courtney Wilkins, Sunil Thomas, Aimee Sekine, Renee C. Ireton, Martin T. Ferris, Duncan M. Hendrick, Kathleen Voss, Fernando Pardo-Manuel de Villena, Ralph Baric, Mark Heise, Michael Gale Jr.
Publikováno v:
Genomics Data, Vol 10, Iss C, Pp 114-117 (2016)
Flaviviruses are hematophagous arthropod-viruses that pose global challenges to human health. Like Zika virus, West Nile Virus (WNV) is a flavivirus for which no approved vaccine exists [1]. The role host genetics play in early detection and response
Externí odkaz:
https://doaj.org/article/f4d2416419f643669e1b8140ab713777
Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses
Autor:
Jeremiah Athmer, Anthony R. Fehr, Matthew E. Grunewald, Wen Qu, D. Lori Wheeler, Kevin W. Graepel, Rudragouda Channappanavar, Aimee Sekine, Dana Saud Aldabeeb, Michael Gale, Mark R. Denison, Stanley Perlman
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA. Lineage A betacoronaviruses incorporate a 95-bp stem-loop structure, the packaging
Externí odkaz:
https://doaj.org/article/3da1a93d54de4efbb6a33718ce452b29
Autor:
Jessica B Graham, Jessica L Swarts, Courtney Wilkins, Sunil Thomas, Richard Green, Aimee Sekine, Kathleen M Voss, Renee C Ireton, Michael Mooney, Gabrielle Choonoo, Darla R Miller, Piper M Treuting, Fernando Pardo Manuel de Villena, Martin T Ferris, Shannon McWeeney, Michael Gale, Jennifer M Lund
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005996 (2016)
Infection with West Nile virus (WNV) leads to a range of disease outcomes, including chronic infection, though lack of a robust mouse model of chronic WNV infection has precluded identification of the immune events contributing to persistent infectio
Externí odkaz:
https://doaj.org/article/1368135a2e7e452780f93435ca1dd3a6
Autor:
Kathleen Voss, Jennifer M. Lund, Richard Green, Sunil Thomas, Jessica L. Swarts, Jessica B. Graham, Aimee Sekine, Michael Gale, Renee C. Ireton
Publikováno v:
The Journal of Infectious Diseases. 219:1162-1171
Background A challenge to the design of improved therapeutic agents and prevention strategies for neuroinvasive infection and associated disease is the lack of known natural immune correlates of protection. A relevant model to study such correlates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e15cd39b3e6de8c0184959a99ff655
https://doi.org/10.1093/infdis/jiy623
https://doi.org/10.1093/infdis/jiy623
Autor:
Duncan M. Hendrick, Michael Gale, Aimee Sekine, Shannon K. McWeeney, Jennifer T. Go, Fernando Pardo-Manuel de Villena, Richard Green, Kathleen Voss, Sunil Thomas, Martin T. Ferris, Gabrielle Choonoo, Renee C. Ireton, Michael Mooney, Courtney Wilkins, Sophia Jeng
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1665-1682 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The oligoadenylate-synthetase (Oas) gene locus provides innate immune resistance to virus infection. In mouse models, variation in the Oas1b gene influences host susceptibility to flavivirus infection. However, the impact of Oas variation on overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158bce23584a49da2d2eadb64c7af7b8
https://doi.org/10.1534/g3.117.041624
https://doi.org/10.1534/g3.117.041624
Autor:
Mark T. Heise, Richard Green, Kathleen Voss, Duncan M. Hendrick, Michael Gale, Sunil Thomas, Fernando Pardo-Manuel de Villena, Ralph S. Baric, Renee C. Ireton, Aimee Sekine, Martin T. Ferris, Courtney Wilkins
Publikováno v:
Genomics Data
Genomics Data, Vol 10, Iss C, Pp 114-117 (2016)
Genomics Data, Vol 10, Iss C, Pp 114-117 (2016)
Flaviviruses are hematophagous arthropod-viruses that pose global challenges to human health. Like Zika virus, West Nile Virus (WNV) is a flavivirus for which no approved vaccine exists [1]. The role host genetics play in early detection and response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c136019fabc19529517d3fdc76f694bc
http://europepmc.org/articles/PMC5097955
http://europepmc.org/articles/PMC5097955
Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses
Autor:
Aimee Sekine, Matthew E. Grunewald, Jeremiah Athmer, Dana Aldabeeb, Kevin W. Graepel, Rudragouda Channappanavar, Wen Qu, D. Lori Wheeler, Anthony R. Fehr, Mark R. Denison, Michael Gale, Stanley Perlman
Publikováno v:
mBio, Vol 9, Iss 3, p e00272-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio
mBio, Vol 9, Iss 3 (2018)
mBio
Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA. Lineage A betacoronaviruses incorporate a 95-bp stem-loop structure, the packaging signal (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4e835a077314244d932a33197bfc3e
https://doaj.org/article/0c7edc7255234ff8827fe3a858f18d6d
https://doaj.org/article/0c7edc7255234ff8827fe3a858f18d6d
Autor:
Richard Green, Courtney Wilkins, Darla R. Miller, Martin T. Ferris, Aimee Sekine, Fernando Pardo-Manuel de Villena, Jennifer M. Lund, Shannon K. McWeeney, Michael Gale, Piper M. Treuting, Sunil Thomas, Gabrielle Choonoo, Jessica B. Graham, Kathleen Voss, Michael Mooney, Renee C. Ireton, Jessica L. Swarts
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 11, p e1005996 (2016)
PLoS Pathogens, Vol 12, Iss 11, p e1005996 (2016)
Infection with West Nile virus (WNV) leads to a range of disease outcomes, including chronic infection, though lack of a robust mouse model of chronic WNV infection has precluded identification of the immune events contributing to persistent infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0300e4b6d6fdc24355358a2c955608
https://pubmed.ncbi.nlm.nih.gov/27806117
https://pubmed.ncbi.nlm.nih.gov/27806117