Integrated multimodal cell atlas of Alzheimer’s disease

Autor: Mariano I. Gabitto, Kyle J. Travaglini, Victoria M. Rachleff, Eitan S. Kaplan, Brian Long, Jeanelle Ariza, Yi Ding, Joseph T. Mahoney, Nick Dee, Jeff Goldy, Erica J. Melief, Krissy Brouner, Jazmin Campos, John Campos, Ambrose J. Carr, Tamara Casper, Rushil Chakrabarty, Michael Clark, Jonah Cool, Nasmil J. Valera Cuevas, Rachel Dalley, Martin Darvas, Song-Lin Ding, Tim Dolbeare, Christine L. Mac Donald, Tom Egdorf, Luke Esposito, Rebecca Ferrer, Rohan Gala, Amanda Gary, Jessica Gloe, Nathan Guilford, Junitta Guzman, Daniel Hirschstein, Windy Ho, Tim Jarksy, Nelson Johansen, Brian E. Kalmbach, Lisa M. Keene, Sarah Khawand, Mitch Kilgore, Amanda Kirkland, Michael Kunst, Brian R. Lee, Jocelin Malone, Zoe Maltzer, Naomi Martin, Rachel McCue, Delissa McMillen, Emma Meyerdierks, Kelly P. Meyers, Tyler Mollenkopf, Mark Montine, Amber L. Nolan, Julie Nyhus, Paul A. Olsen, Maiya Pacleb, Nicholas Peña, Thanh Pham, Christina Alice Pom, Nadia Postupna, Augustin Ruiz, Aimee M. Schantz, Nadiya V. Shapovalova, Staci A. Sorensen, Brian Staats, Matt Sullivan, Susan M. Sunkin, Carol Thompson, Michael Tieu, Jonathan Ting, Amy Torkelson, Tracy Tran, Ming-Qiang Wang, Jack Waters, Angela M. Wilson, David Haynor, Nicole Gatto, Suman Jayadev, Shoaib Mufti, Lydia Ng, Shubhabrata Mukherjee, Paul K. Crane, Caitlin S. Latimer, Boaz P. Levi, Kimberly Smith, Jennie L. Close, Jeremy A. Miller, Rebecca D. Hodge, Eric B. Larson, Thomas J. Grabowski, Michael Hawrylycz, C. Dirk Keene, Ed S. Lein

Alzheimer’s disease (AD) is the most common cause of dementia in older adults. Neuropathological and imaging studies have demonstrated a progressive and stereotyped accumulation of protein aggregates, but the underlying molecular and cellular mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3819862faf9d0f4384328a779b869e30
https://doi.org/10.1101/2023.05.08.539485

Protocol for the Systematic Fixation, Circuit-Based Sampling, and Qualitative and Quantitative Neuropathological Analysis of Human Brain Tissue

Autor: Caitlin S, Latimer, Erica J, Melief, Jeanelle, Ariza-Torres, Kim, Howard, Amanda R, Keen, Lisa M, Keene, Aimee M, Schantz, Trevor M, Sytsma, Angela M, Wilson, Thomas J, Grabowski, Martin, Darvas, Kristen Dams, O'Connor, Amber L, Nolan, Brian L, Edlow, Christine L, Mac Donald, C Dirk, Keene

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2561

Human brain tissue has long been a critical resource for neuroanatomy and neuropathology, but with the advent of advanced imaging and molecular sequencing techniques, it has become possible to use human brain tissue to study, in great detail, the str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1109f3b350971f9791af3c46290150d2
https://pubmed.ncbi.nlm.nih.gov/36399262