Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aimee M Juan"'
Autor:
Shaday Michan, Aimee M Juan, Christian G Hurst, Zhenghao Cui, Lucy P Evans, Colman J Hatton, Dorothy T Pei, Meihua Ju, David A Sinclair, Lois E H Smith, Jing Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85031 (2014)
Proliferative retinopathy is a leading cause of blindness, including retinopathy of prematurity (ROP) in children and diabetic retinopathy in adults. Retinopathy is characterized by an initial phase of vessel loss, leading to tissue ischemia and hypo
Externí odkaz:
https://doaj.org/article/9e52085956a84969910e9d7eead06e5e
Autor:
Zhuo Shao, Mollie Friedlander, Christian G Hurst, Zhenghao Cui, Dorothy T Pei, Lucy P Evans, Aimee M Juan, Houda Tahiri, François Duhamel, Jing Chen, Przemyslaw Sapieha, Sylvain Chemtob, Jean-Sébastien Joyal, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69552 (2013)
Angiogenesis of the microvasculature is central to the etiology of many diseases including proliferative retinopathy, age-related macular degeneration and cancer. A mouse model of microvascular angiogenesis would be very valuable and enable access to
Externí odkaz:
https://doaj.org/article/f1702bd7523d451ea79e799da8f27bc0
Autor:
Tadanori Mammoto, Elisabeth Jiang, Amanda Jiang, Yongbo Lu, Aimee M Juan, Jing Chen, Akiko Mammoto
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73407 (2013)
Tight regulation of vascular permeability is necessary for normal development and deregulated vascular barrier function contributes to the pathogenesis of various diseases, including acute respiratory distress syndrome, cancer and inflammation. The a
Externí odkaz:
https://doaj.org/article/c943198a1c20484c9e3b1ea0d3ce48da
Autor:
Jing Chen, Andreas Stahl, Nathan M Krah, Molly R Seaward, Jean-Sebastian Joyal, Aimee M Juan, Colman J Hatton, Christopher M Aderman, Roberta J Dennison, Keirnan L Willett, Przemyslaw Sapieha, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30203 (2012)
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype
Externí odkaz:
https://doaj.org/article/b95b34056b594302b9b6d0fd3915b137
Autor:
Aimee M, Juan, Yee Hoon, Foong, Joanne L, Thorvaldsen, Yemin, Lan, Nicolae A, Leu, Joel G, Rurik, Li, Li, Christopher, Krapp, Casey L, Rosier, Jonathan A, Epstein, Marisa S, Bartolomei
Publikováno v:
Molecular Cell. 82:3613-3631.e7
Allele-specific expression of imprinted gene clusters is governed by gametic DNA methylation at master regulators called imprinting control regions (ICRs). Non-gametic or secondary differentially methylated regions (DMRs) at promoters and exonic regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da430c918441cf018953c45499e4a3d
https://doi.org/10.1016/j.molcel.2022.08.021
https://doi.org/10.1016/j.molcel.2022.08.021
Autor:
Zhuo Shao, Mollie Friedlander, Christian G. Hurst, Zhenghao Cui, Dorothy T. Pei, Lucy P. Evans, Aimee M. Juan, Houda Tahiri, François Duhamel, Jing Chen, Przemyslaw Sapieha, Sylvain Chemtob, Jean-Sébastien Joyal, Lois E. H. Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/bea40d8bbf514a4faebd184d4fde109f
Autor:
Aimee M. Juan, Marisa S. Bartolomei
Publikováno v:
Genes & Development. 33:1-3
The monoallelic parent of origin-specific expression of imprinted genes in mammals is regulated by differentially DNA methylated imprinting control regions (ICRs). In contrast to most of the genome, ICRs must maintain their DNA methylation and parent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccf8ad2e76b19bfe7b45fc181d76055
https://doi.org/10.1101/gad.322990.118
https://doi.org/10.1101/gad.322990.118
Autor:
Zhenghao Cui, David A. Sinclair, Aimee M. Juan, Dorothy T. Pei, Jean-Sébastien Joyal, Lucy P. Evans, Christian G. Hurst, Lois E.H. Smith, Przemyslaw Sapieha, Andreas Stahl, Shaday Michan, Colman J. Hatton, Jing Chen
Publikováno v:
Angiogenesis. 16:985-992
Regeneration of blood vessels in ischemic neuronal tissue is critical to reduce tissue damage in diseases. In proliferative retinopathy, initial vessel loss leads to retinal ischemia, which can induce either regrowth of vessels to restore normal meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ad7fdad45ff50c201622aa80d59bb2
https://doi.org/10.1007/s10456-013-9374-5
https://doi.org/10.1007/s10456-013-9374-5
Autor:
Andreas Stahl, Agustin Cerani, Flavio A. Rezende, Nicholas Sitaras, Dominique Leboeuf, Eric Milot, Gaelle Mawambo, Eric Lapalme, Martin Guimond, Aimee M. Juan, Sophie Tremblay, Francois Binet, Nicolas Tetreault, Sandra Favret, Jean-Sébastien Joyal, Randal J. Kaufman, Timothy E. Kennedy, Przemyslaw Sapieha
Publikováno v:
Cell Metabolism. 17:353-371
SummaryIn stroke and proliferative retinopathy, despite hypoxia driven angiogenesis, delayed revascularization of ischemic tissue aggravates the loss of neuronal function. What hinders vascular regrowth in the ischemic central nervous system remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c673d3556e4fc8c4942365ac7bd4ab1
https://doi.org/10.1016/j.cmet.2013.02.003
https://doi.org/10.1016/j.cmet.2013.02.003
Autor:
Kerry A. Pierce, Clary B. Clish, Michael B. Powner, Lucy P. Evans, Marin L. Gantner, Alan B. Packard, Edith Aguilar, Jin Sung Kim, Zhuo Shao, Jing Chen, Zhongjie Fu, Samuel B. Burnim, Ye Sun, Bruno Maranda, Aimee M. Juan, Martin Friedlander, Przemyslaw Sapieha, Christian G. Hurst, Nicholas Saba, Emile Levy, Colman J. Hatton, Flavio A. Rezende, Thomas Fredrick, Gauri Patel, Marcus Fruttiger, Patrick Bherer, Lois E.H. Smith, Zhenghao Cui, Michel Boisvert, Kristis Vevis, Jean-Sébastien Joyal
Publikováno v:
Nature medicine
Tissues with high metabolic rates often use lipid as well as glucose for energy, conferring a survival advantage during feast and famine.1 Current dogma suggests that high-energy consuming photoreceptors depend on glucose.2,3 Here we show that retina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd62a1bd9c8f80590c7ec5696b6e670
https://pubmed.ncbi.nlm.nih.gov/26974308
https://pubmed.ncbi.nlm.nih.gov/26974308