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pro vyhledávání: '"Aimee Lake"'
Autor:
Aimee Lake, Mark T. Bedford
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 618:91-101
DNA is under constant attack from intracellular and external mutagens. Sites of DNA damage need to be pinpointed so that the DNA repair machinery can be mobilized to the proper location. The identification of damaged sites, recruitment of repair fact
Autor:
Jeremy J. Daniel, Li Xia, Murli Krishna, Alexsandra Espejo, Aimee Lake, Jeesun Kim, Mark T. Bedford, Yi Zhang
Publikováno v:
EMBO reports. 7:397-403
The post-translational modification of histones regulates many cellular processes, including transcription, replication and DNA repair. A large number of combinations of post-translational modifications are possible. This cipher is referred to as the
Autor:
LeAnn J. Howe, Kay L. Walter, Xiaobing Shi, Steve M. Chan, Paul J. Utz, Alexey Lugovskoy, Aimee Lake, Jen Hao A. Kuo, Mark T. Bedford, Scott D. Briggs, Foteini Davrazou, David G. E. Martin, Or Gozani, Tatiana G. Kutateladze, Ian M. Fingerman, Ioulia Kachirskaia
Publikováno v:
The Journal of biological chemistry. 282(4)
The PHD finger motif is a signature chromatin-associated motif that is found throughout eukaryotic proteomes. Here we have determined the histone methyl-lysine binding activity of the PHD fingers present within the Saccharomyces cerevisiae proteome.