Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Aimee L. Kenoyer"'
Autor:
Kevin P. Labadie, Adrienne L. Lehnert, Aimee L. Kenoyer, Donald K. Hamlin, Andrew D. Ludwig, Alan F. Utria, Sara K. Daniel, Tara N. Mihailovic, Alexander Prossnitz, Johnnie J. Orozco, Yawen Li, D. Scott Wilbur, Robert S. Miyaoka, James O. Park
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Background Early intrahepatic recurrence is common after surgical resection of hepatocellular carcinoma (HCC) and leads to increased morbidity and mortality. Insensitive and nonspecific diagnostic imaging contributes to EIR and results in mi
Externí odkaz:
https://doaj.org/article/de5efabc7d0b4c4991c791912e3e2374
Autor:
Kevin P. Labadie, Andrew D. Ludwig, Adrienne L. Lehnert, Donald K. Hamlin, Aimee L. Kenoyer, Kevin M. Sullivan, Sara K. Daniel, Tara N. Mihailovic, Jonathan G. Sham, Johnnie J. Orozco, Raymond S. Yeung, Delphine L. Chen, D. Scott Wilbur, Robert S. Miyaoka, James O. Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Glypican-3 (GPC3) is a tumor associated antigen expressed by hepatocellular carcinoma (HCC) cells. This preclinical study evaluated the efficacy of a theranostic platform using a GPC3-targeting antibody αGPC3 conjugated to zirconium-89 (89Z
Externí odkaz:
https://doaj.org/article/ddea22e7449b4b418c2f02ca24983fd2
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Pretargeted radioimmunotherapy (PRIT) has been investigated as a multi-step approach to decrease relapse and toxicity for high-risk acute myeloid leukemia (AML). Relevant factors including endogenous biotin and immunogenicity, however, have limited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cb196c04e590eb312858a4d9061fed
https://doi.org/10.1158/1535-7163.c.6542662
https://doi.org/10.1158/1535-7163.c.6542662
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Supplementary Materials, Methods and relevant AA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c057d8965675ca7f790ca8236eb48a
https://doi.org/10.1158/1535-7163.22520518.v1
https://doi.org/10.1158/1535-7163.22520518.v1
Autor:
Oliver W. Press, Brian G. Till, Amelia Waltman, Theodore A. Gooley, Mark D. Hylarides, Darrell R. Fisher, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco, Ajay K. Gopal, Damian J. Green, Shyril O'Steen
Table S1 presents mouse survival data for in vivo experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1f8931fda4e9dec0f52f77d94c1a28
https://doi.org/10.1158/0008-5472.22414092.v1
https://doi.org/10.1158/0008-5472.22414092.v1
Autor:
Oliver W. Press, K. Dane Wittrup, D. Scott Wilbur, Kelly D. Orcutt, Shyril O'Steen, Brian G. Till, Johnnie J. Orozco, Theodore A. Gooley, Ajay K. Gopal, Mark D. Hylarides, Aimee L. Kenoyer, Sofia H.L. Frost, Darrell R. Fisher, Donald K. Hamlin, Yukang Lin, Shani L. Frayo, Damian J. Green
Figures including: Supplemental Figure 1- Dose finding pharmacokinetics. Supplemental Figure 2- Dose finding tissue biodistribution. Supplemental Figure 3- body weight over time in a therapy study. Supplemental Figure 4- blood counts over time in a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fa9ad6c582f79e53958516ac3c2d49
https://doi.org/10.1158/0008-5472.22413027
https://doi.org/10.1158/0008-5472.22413027
Autor:
Oliver W. Press, K. Dane Wittrup, D. Scott Wilbur, Kelly D. Orcutt, Shyril O'Steen, Brian G. Till, Johnnie J. Orozco, Theodore A. Gooley, Ajay K. Gopal, Mark D. Hylarides, Aimee L. Kenoyer, Sofia H.L. Frost, Darrell R. Fisher, Donald K. Hamlin, Yukang Lin, Shani L. Frayo, Damian J. Green
Streptavidin (SA)-biotin pretargeted radioimmunotherapy (PRIT) that targets CD20 in non-Hodgkin lymphoma (NHL) exhibits remarkable efficacy in model systems, but SA immunogenicity and interference by endogenous biotin may complicate clinical translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dc53f403d5241580b8113781f0a0c07
https://doi.org/10.1158/0008-5472.c.6508593.v1
https://doi.org/10.1158/0008-5472.c.6508593.v1
Autor:
Oliver W. Press, John M. Pagel, Damian J. Green, Ajay K. Gopal, Amanda Axtman, Aimee L. Kenoyer, Franz Buchegger, Mark Hylarides, Nural Orgun, Patrick S. Stayton, D. Scott Wilbur, Yukang Lin, Donald K. Hamlin, Shani M. Frayo, Jaideep Shenoi, Steven I. Park
Purpose: Pretargeted radioimmunotherapy (PRIT) using streptavidin (SAv)-biotin technology can deliver higher therapeutic doses of radioactivity to tumors than conventional RIT. However, “endogenous” biotin can interfere with the effectiveness of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac83bf1161f96c54d74b350d1a496f57
https://doi.org/10.1158/1078-0432.c.6519756
https://doi.org/10.1158/1078-0432.c.6519756
Autor:
Oliver W. Press, John M. Pagel, Damian J. Green, Ajay K. Gopal, Amanda Axtman, Aimee L. Kenoyer, Franz Buchegger, Mark Hylarides, Nural Orgun, Patrick S. Stayton, D. Scott Wilbur, Yukang Lin, Donald K. Hamlin, Shani M. Frayo, Jaideep Shenoi, Steven I. Park
PDF file - 112K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcb81c04719eeba642321f5e20943e6
https://doi.org/10.1158/1078-0432.22443294
https://doi.org/10.1158/1078-0432.22443294
Autor:
Oliver W. Press, Brian G. Till, Amelia Waltman, Theodore A. Gooley, Mark D. Hylarides, Darrell R. Fisher, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco, Ajay K. Gopal, Damian J. Green, Shyril O'Steen
Constitutive B-cell receptor signaling leads to overexpression of the antiapoptotic BCL-2 protein and is implicated in the pathogenesis of many types of B-cell non-Hodgkin lymphoma (B-NHL). The BCL-2 small-molecule inhibitor venetoclax shows promisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba29fc239fe41412deedcbacf1fa7d0
https://doi.org/10.1158/0008-5472.c.6508887.v1
https://doi.org/10.1158/0008-5472.c.6508887.v1