Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aimee J Aylward"'
Autor:
Vicky Chou, Richard V. Pearse, Aimee J. Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B. Fancher, Alina Sigalov, Courtney R. Benoit, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Philip L. De Jager, Vilas Menon, Tracy L. Young-Pearse
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Microglia and neuroinflammation play an important role in the development and progression of Alzheimer’s disease (AD). Inositol polyphosphate-5-phosphatase D (INPP5D/SHIP1) is a myeloid-expressed gene genetically-associated with AD. Throug
Externí odkaz:
https://doaj.org/article/9e3d8cd8d32347f6b00af0ac1594f3b7
Autor:
Hyo Lee, Aimee J. Aylward, Richard V. Pearse, II, Alexandra M. Lish, Yi-Chen Hsieh, Zachary M. Augur, Courtney R. Benoit, Vicky Chou, Allison Knupp, Cheryl Pan, Srilakshmi Goberdhan, Duc M. Duong, Nicholas T. Seyfried, David A. Bennett, Mariko F. Taga, Kevin Huynh, Matthias Arnold, Peter J. Meikle, Philip L. De Jager, Vilas Menon, Jessica E. Young, Tracy L. Young-Pearse
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112994- (2023)
Summary: SORL1 is implicated in the pathogenesis of Alzheimer’s disease (AD) through genetic studies. To interrogate the roles of SORL1 in human brain cells, SORL1-null induced pluripotent stem cells (iPSCs) were differentiated to neuron, astrocyte
Externí odkaz:
https://doaj.org/article/911ab12d4ed045b69c2a0c7474867a7a
Autor:
Hyo Lee, Aimee J. Aylward, Richard V. Pearse, Yi-Chen Hsieh, Zachary M. Augur, Courtney R. Benoit, Vicky Chou, Allison Knupp, Cheryl Pan, Srilakshmi Goberdhan, Duc M. Duong, Nicholas T. Seyfried, David A. Bennett, Hans-Ulrich Klein, Philip L. De Jager, Vilas Menon, Jessica E. Young, Tracy L. Young-Pearse
Publikováno v:
bioRxiv
SummarySORL1 is strongly implicated in the pathogenesis of Alzheimer’s disease (AD) through human genetic studies that point to an association of reduced SORL1 levels with higher risk for AD. To interrogate the role(s) of SORL1 in human brain cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5ca35d64f619357003633b6b32402a
https://doi.org/10.1101/2023.02.25.530017
https://doi.org/10.1101/2023.02.25.530017
Autor:
Hyo Lee, Aimee J Aylward, Richard V Pearse II, Yi‐Chen Hsieh, Zachary M Augur, Allison Knupp, Srilakshmi Goberdhan, Cheryl Pan, Nicholas T. Seyfried, David A Bennett, Philip L De Jager, Jessica E. Young, Tracy Young‐Pearse
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb64be854043477358ee61d7d654876
https://doi.org/10.1002/alz.067209
https://doi.org/10.1002/alz.067209