Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aimee Frazier"'
Autor:
Komal Jhaveri, Haeseong Park, James Waisman, Jonathan W Goldman, Angel Guerrero-Zotano, Valentina Boni, Barbara Haley, Ingrid A Mayer, Adam Brufsky, Eddy S Yang, José A García-Sáenz, François-Clement Bidard, John Crown, Bo Zhang, Aimee Frazier, Irmina Diala, Lisa D Eli, Brian Barnett, Hans Wildiers
Publikováno v:
Cancer Research. 82:GS4-10
Background: HER2 mutations are oncogenic drivers in a subset of metastatic breast cancers (MBC). Neratinib (N) is an oral, irreversible pan-HER tyrosine kinase inhibitor with preclinical and clinical activity against HER2 mutations. Genomic analyses
Autor:
Larisa Ryvo, Suzette Delaloge, Judith Bebchuk, Maureen E. Trudeau, William J. Gradishar, Ming-Shen Dai, Richard A. Bryce, Sung-Bae Kim, Aimee Frazier, Mafalda Oliveira, Adam Brufsky, Kiana Keyvanjah, Luciana Landeiro, Sara A. Hurvitz, Barbara Haley, Cristina Saura, Ron Bose, Beverly Moy
Publikováno v:
Cancer Research. 81:PD13-09
Background: The development of central nervous system (CNS) metastases presents a considerable challenge in metastatic breast cancer (MBC) due to the limited availability of evidence-based treatments. Up to 50% of patients with HER2-positive (HER2+)