Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Aimee Fourie-O'Donohue"'
Autor:
Aimee Fourie-O’Donohue, Phillip Y. Chu, Josefa dela Cruz Chuh, Robert Tchelepi, Siao Ping Tsai, John C. Tran, William S. Sawyer, Dian Su, Carl Ng, Keyang Xu, Shang-Fan Yu, Thomas H. Pillow, Jack Sadowsky, Peter S. Dragovich, Yichin Liu, Katherine R. Kozak
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
For antibody-drug conjugates to be efficacious and safe, they must be stable in circulation to carry the payload to the site of the targeted cell. Several components of a drug-conjugated antibody are known to influence stability: 1) the site of drug
Externí odkaz:
https://doaj.org/article/e46e20ec184a4063ba55b87d5b9f2d28
Autor:
Susan D. Spencer, Mark S. Dennis, Sarajane Ross, Katherine R. Kozak, Aimee Fourie-O'Donohue, Gladys S. Ingle, Yin Zhang, Josefa Chuh, Elizabeth Luis, Vivian Barry-Hamilton, Linda Rangell, Hartmut Koeppen, Dorothy M. French, Ron Firestein, Glenn Pacheco, Nidhi Gupta, Suzie J. Scales
Supplementary Figure 1: IHC validation of anti-mesothelin antibody 19C3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b2e5317ebffc744b644e2646c06691
https://doi.org/10.1158/1535-7163.22501794.v1
https://doi.org/10.1158/1535-7163.22501794.v1
Autor:
Susan D. Spencer, Mark S. Dennis, Sarajane Ross, Katherine R. Kozak, Aimee Fourie-O'Donohue, Gladys S. Ingle, Yin Zhang, Josefa Chuh, Elizabeth Luis, Vivian Barry-Hamilton, Linda Rangell, Hartmut Koeppen, Dorothy M. French, Ron Firestein, Glenn Pacheco, Nidhi Gupta, Suzie J. Scales
Supplementary Table 2: Details of in vivo efficacy studies (# cells implanted; mouse strain, age and weight; tumor randomization volumes and IHC scores; % tumor growth inhibition and time to doubling versus vehicle).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a90c2eab2405a86d366643a0bc81d6
https://doi.org/10.1158/1535-7163.22501773
https://doi.org/10.1158/1535-7163.22501773
Autor:
Susan D. Spencer, Mark S. Dennis, Sarajane Ross, Katherine R. Kozak, Aimee Fourie-O'Donohue, Gladys S. Ingle, Yin Zhang, Josefa Chuh, Elizabeth Luis, Vivian Barry-Hamilton, Linda Rangell, Hartmut Koeppen, Dorothy M. French, Ron Firestein, Glenn Pacheco, Nidhi Gupta, Suzie J. Scales
Supplementary Table 1: Summary of 5B2 anti-mesothelin IHC literature and TMA details.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d497fc929ae9d73af4196930e0c3172
https://doi.org/10.1158/1535-7163.22501776
https://doi.org/10.1158/1535-7163.22501776
Autor:
Susan D. Spencer, Mark S. Dennis, Sarajane Ross, Katherine R. Kozak, Aimee Fourie-O'Donohue, Gladys S. Ingle, Yin Zhang, Josefa Chuh, Elizabeth Luis, Vivian Barry-Hamilton, Linda Rangell, Hartmut Koeppen, Dorothy M. French, Ron Firestein, Glenn Pacheco, Nidhi Gupta, Suzie J. Scales
Supplemental ancillary methods (ELISA, surface plasmon resonance and humanization) and 4 supplemental figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b35fe9f3317ec9ed5c02b37f7fed0df
https://doi.org/10.1158/1535-7163.22501782.v1
https://doi.org/10.1158/1535-7163.22501782.v1
Autor:
Jagath R. Junutula, Paul Polakis, Richard H. Scheller, Mark S. Dennis, Deepak Sampath, Jo-Anne Hongo, Helga Raab, Katherine R. Kozak, Aimee Fourie-O'Donohue, Ron Firestein, Robert Piskol, Eric Cheng, Mary Ann T. Go, Kirsten A. Poon, Fiona Zhong, Rachana Ohri, Coenraad Kuijl, Dongwei Li, Melissa M. Schutten, Meredith Hazen, Yvonne Chen, Lisa M. Crocker, Sunil Bhakta
Luminal A (hormone receptor-positive) breast cancer constitutes 70% of total breast cancer patients. In an attempt to develop a targeted therapeutic for this cancer indication, we have identified and characterized Glial cell line–Derived Neurotroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ebbf88322d045b6d0c4b08c2c22021d
https://doi.org/10.1158/1535-7163.c.6537960.v1
https://doi.org/10.1158/1535-7163.c.6537960.v1
Autor:
Jagath R. Junutula, Paul Polakis, Richard H. Scheller, Mark S. Dennis, Deepak Sampath, Jo-Anne Hongo, Helga Raab, Katherine R. Kozak, Aimee Fourie-O'Donohue, Ron Firestein, Robert Piskol, Eric Cheng, Mary Ann T. Go, Kirsten A. Poon, Fiona Zhong, Rachana Ohri, Coenraad Kuijl, Dongwei Li, Melissa M. Schutten, Meredith Hazen, Yvonne Chen, Lisa M. Crocker, Sunil Bhakta
Figure S1. Validation of anti-GFRA1 antibodies (R&D systems and GNE-8H6) for the use of Immunohistochemistry (IHC) analysis; Figure S2. ELISA analyses to test binding specificity of anti-GFRA1 antibodies to GFRA1 (A) and GFRA2 (B) extra cellular doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100a6557ca8c0f2a229a1ced8e41d71e
https://doi.org/10.1158/1535-7163.22505118
https://doi.org/10.1158/1535-7163.22505118
Autor:
Susan D. Spencer, Mark S. Dennis, Sarajane Ross, Katherine R. Kozak, Aimee Fourie-O'Donohue, Gladys S. Ingle, Yin Zhang, Josefa Chuh, Elizabeth Luis, Vivian Barry-Hamilton, Linda Rangell, Hartmut Koeppen, Dorothy M. French, Ron Firestein, Glenn Pacheco, Nidhi Gupta, Suzie J. Scales
Supplementary Figure 2: IHC validation of anti-mesothelin antibody SP74.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ca9ca3dff4c4a31a7774d1ede47b7d
https://doi.org/10.1158/1535-7163.22501791
https://doi.org/10.1158/1535-7163.22501791
Autor:
Susan D. Spencer, Mark S. Dennis, Sarajane Ross, Katherine R. Kozak, Aimee Fourie-O'Donohue, Gladys S. Ingle, Yin Zhang, Josefa Chuh, Elizabeth Luis, Vivian Barry-Hamilton, Linda Rangell, Hartmut Koeppen, Dorothy M. French, Ron Firestein, Glenn Pacheco, Nidhi Gupta, Suzie J. Scales
Supplementary Figure 4: Western blots of cell lines and xenografts used in Figure 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d071c4c1b4e156a91b28eecb13fb1707
https://doi.org/10.1158/1535-7163.22501785
https://doi.org/10.1158/1535-7163.22501785
Autor:
Jennifer A. Lacap, Shang-Fan Yu, Eduardo E. Mundo, Leslie A. Khawli, Crystal Zhang, C. Andrew Boswell, Kedan Lin, Sheila Ulufatu, Daniela Bumbaca Yadav, Gregory Z. Ferl, Aimee Fourie-O'Donohue, Jason Ho, Katherine R. Kozak
Publikováno v:
Oncotarget
TENB2, a transmembrane proteoglycan protein, is a promising target for antibody drug conjugate (ADC) therapy due to overexpression in human prostate tumors and rapid internalization. We previously characterized how predosing with parental anti-TENB2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07cb4ba1ada3ba78bda2180d608a72f
https://doi.org/10.18632/oncotarget.27263
https://doi.org/10.18632/oncotarget.27263