Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aimee E. Belanger"'
Autor:
Thomas R. Shryock, Aimee E. Belanger
Publikováno v:
Journal of Antimicrobial Chemotherapy. 60:715-723
The use of macrolide antibiotics in food animals has the potential to select for macrolide-resistant strains of resident bacterial flora. This may include the animal pathogens that are the intended targets of macrolide antibiotic intervention and Cam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9164c9cd72a94852e6470a33d78413
https://doi.org/10.1093/jac/dkm300
https://doi.org/10.1093/jac/dkm300
Publikováno v:
Journal of Bacteriology. 186:8164-8171
In pioneering studies, Avery et al. identified DNA as the hereditary material (A. T. Avery, C. M. MacLeod, and M. McCarty, J. Exp. Med. 79 :137-158, 1944). They demonstrated, by means of variation in colony morphology, that this substance could trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bb19516ded905132568a43d276e5dd
https://doi.org/10.1128/jb.186.24.8164-8171.2004
https://doi.org/10.1128/jb.186.24.8164-8171.2004
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:2507-2512
Described here are the development and validation of a novel approach to identify genes encoding drug targets in Streptococcus pneumoniae . The method relies on the use of an ordered genomic library composed of PCR amplicons that were generated under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023c771bd870d750e3ab6ab55196aa28
https://doi.org/10.1128/aac.46.8.2507-2512.2002
https://doi.org/10.1128/aac.46.8.2507-2512.2002
Autor:
Aimee E. Belanger, Graham F. Hatfull
Publikováno v:
Journal of Bacteriology. 181:6670-6678
Bacterial glycogen is a polyglucose storage compound that is thought to prolong viability during stationary phase. However, a specific role for glycogen has not been determined. We have characterized SMEG53, a temperature-sensitive mutant of Mycobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111acff7c101e90c1009e99b936af76a
https://doi.org/10.1128/jb.181.21.6670-6678.1999
https://doi.org/10.1128/jb.181.21.6670-6678.1999
Publikováno v:
Journal of Molecular Biology. 279:143-164
Mycobacteriophage D29 is a lytic phage that infects both fast and slow-growing mycobacterial species. The complete genome sequence of D29 reveals that it is a close relative of the temperate mycobacteriophage L5, whose sequence has been described pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfcd010adad88449b15c21f22274f3e5
https://doi.org/10.1006/jmbi.1997.1610
https://doi.org/10.1006/jmbi.1997.1610
Autor:
Patrick J. Brennan, Katarína Mikušová, Julia M. Inamine, Michael E. Ford, Aimee E. Belanger, John T. Belisle, Gurdyal S. Besra
Publikováno v:
Proceedings of the National Academy of Sciences. 93:11919-11924
The antimycobacterial compound ethambutol [Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol] is used to treat tuberculosis as well as disseminated infections caused by Mycobacterium avium. The critical target for Emb lies in the pathway for the biosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29931aa88bc20b82b86e8e10273d6223
https://doi.org/10.1073/pnas.93.21.11919
https://doi.org/10.1073/pnas.93.21.11919
Publikováno v:
Current opinion in microbiology. 5(3)
Streptococcus pneumoniae is a useful tool for the discovery of broad-spectrum antibiotics because of its genetic malleability and importance as a pathogen. Recent publications of complete chromosomal DNA sequences for S. pneumoniae facilitate rapid a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5e89c8147f8c5aa8e93d53bbd444f9
https://pubmed.ncbi.nlm.nih.gov/12057692
https://pubmed.ncbi.nlm.nih.gov/12057692
Publikováno v:
Journal of bacteriology. 182(23)
A temperature-sensitive mutant of Mycobacterium smegmatis was characterized that contains a mutation in ddlA , the gene encoding d -alanine: d -alanine ligase. Enzymatic assays using recombinant proteins and d -cycloserine susceptibility indicate tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded500e4ed18450a2e5948a6f4bd1a13
https://pubmed.ncbi.nlm.nih.gov/11073937
https://pubmed.ncbi.nlm.nih.gov/11073937
Autor:
Patrick J. Brennan, Aimee E. Belanger, Marcy Peteroy, Dalya Rosner, Anatoly Severin, Nancy D. Connell, Hataichanok Scherman, Frances Zhao, Bohdan Harvey, Graham F. Hatfull, Uri Lopatin
Publikováno v:
Antimicrobial agents and chemotherapy. 44(6)
A mutant of Mycobacterium smegmatis has been isolated that is simultaneously resistant to both d -cycloserine ( d -CS) and vancomycin. Genetic complementation with a PBP4 homolog restores sensitivity to both drugs. Resistance to d -CS and vancomycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeed241a6e800429ed4d6175e6ec673b
https://pubmed.ncbi.nlm.nih.gov/10817733
https://pubmed.ncbi.nlm.nih.gov/10817733
Publikováno v:
Journal of bacteriology. 180(1)
We have isolated a UV-induced temperature-sensitive mutant of Mycobacterium smegmatis that fails to grow at 42°C and exhibits a filamentous phenotype following incubation at the nonpermissive temperature, reminiscent of a defect in cell division. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09f612aab310fc17305becc2f2e1be8
https://pubmed.ncbi.nlm.nih.gov/9422594
https://pubmed.ncbi.nlm.nih.gov/9422594