Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aimee Culverhouse"'
Autor:
Bronwyn M. Kivell, Kelly F. Paton, Nitin Kumar, Aashish S. Morani, Aimee Culverhouse, Amy Shepherd, Susan A. Welsh, Andrew Biggerstaff, Rachel S. Crowley, Thomas E. Prisinzano
Publikováno v:
Molecules, Vol 23, Iss 10, p 2602 (2018)
The acute activation of kappa opioid receptors (KOPr) produces antinociceptive and anti-cocaine effects, however, their side-effects have limited further clinical development. Mesyl Sal B is a potent and selective KOPr analogue of Salvinorin A (Sal A
Externí odkaz:
https://doaj.org/article/b7c703a3687e4e638f6d6d30eadc40f1
Autor:
Peter J. Bosch, Rachel Saylor Crowley, Aimee Culverhouse, Benjamin Neuenswander, Bronwyn M. Kivell, Amy Ewald, Thomas E. Prisinzano
Publikováno v:
Psychopharmacology. 234(16)
Kappa-opioid receptor (KOPr) agonists have pre-clinical anti-cocaine and analgesic effects. However, side effects including sedation, dysphoria, aversion, anxiety and depression limit their therapeutic development. The unique structure of salvinorin
Publikováno v:
Drug and Alcohol Dependence. 171:e106
Publikováno v:
Drug and Alcohol Dependence. 156:e114