Výsledky vyhledávání - "Aime K. Johnson"

Akademický článek

Whole-Genome Shotgun Metagenomic Sequencing Reveals Distinct Gut Microbiome Signatures of Obese Cats

Autor: Xiaolei Ma, Emily Brinker, Emily C. Graff, Wenqi Cao, Amanda L. Gross, Aime K. Johnson, Chao Zhang, Douglas R. Martin, Xu Wang

Publikováno v: Microbiology Spectrum, Vol 10, Iss 3 (2022)

ABSTRACT Overweight and obesity are growing health problems in domestic cats, increasing the risks of insulin resistance, lipid dyscrasias, neoplasia, cardiovascular disease, and decreasing longevity. The signature of obesity in the feline gut microb

Externí odkaz: https://doaj.org/article/25c48efbb287439db94532316398eb51

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Akademický článek

Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy

Autor: Heather L. Gray-Edwards, Xuntian Jiang, Ashley N. Randle, Amanda R. Taylor, Taylor L. Voss, Aime K. Johnson, Victoria J. McCurdy, Miguel Sena-Esteves, Daniel S. Ory, Douglas R. Martin

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 6, Iss C, Pp 135-142 (2017)

GM1 gangliosidosis is a fatal lysosomal disorder, for which there is no effective treatment. Adeno-associated virus (AAV) gene therapy in GM1 cats has resulted in a greater than 6-fold increase in lifespan, with many cats remaining alive at >5.7 year

Externí odkaz: https://doaj.org/article/3e3a1ecbcf1a457a8a1a35bcff0c25d7

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Akademický článek

AAV-Mediated Gene Delivery in a Feline Model of Sandhoff Disease Corrects Lysosomal Storage in the Central Nervous System

Autor: Hannah E. Rockwell, Victoria J. McCurdy, Samuel C. Eaton, Diane U. Wilson, Aime K. Johnson, Ashley N. Randle, Allison M. Bradbury, Heather L. Gray-Edwards, Henry J. Baker, Judith A. Hudson, Nancy R. Cox, Miguel Sena-Esteves, Thomas N. Seyfried, Douglas R. Martin

Publikováno v: ASN Neuro, Vol 7 (2015)

Sandhoff disease (SD) is an autosomal recessive neurodegenerative disease caused by a mutation in the gene for the β-subunit of β-N-acetylhexosaminidase (Hex), resulting in the inability to catabolize ganglioside GM2 within the lysosomes. SD presen

Externí odkaz: https://doaj.org/article/ca9dfbf3374b4466a2748535a40d9de2

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Rabies: who should care?

Autor: Henry J, Baker, Douglas R, Martin, Amanda L, Gross, Manuel F, Chamorro, Maria C, Naskou, Aime K, Johnson, Kenny V, Brock, Kent R, Van Kampen, Rodney E, Willoughby

Publikováno v: Journal of the American Veterinary Medical Association. :1-5

Rabies is the deadliest viral infection known, with no reliable treatment, and although it is entirely preventable, rabies continues to kill more than 60,000 people every year, mostly children in countries where dog rabies is endemic. America is only

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2720be7178fe1dc835945488f987400
https://doi.org/10.2460/javma.22.09.0420

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Normal feline reproduction: The tom

Autor: Aime K, Johnson

Publikováno v: Journal of Feline Medicine and Surgery. 24:212-220

Practical relevance: Understanding the normal reproductive anatomy and physiology of the male cat is important for successful breeding. Veterinarians may be called in to troubleshoot when fertility and pregnancy rates decrease in a cattery. By unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c78dc0aab56185f37b179434fb96fb
https://doi.org/10.1177/1098612x221079707

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