Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aimée, Parker"'
Autor:
Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery, Simon R. Carding
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-25 (2022)
Abstract Background Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias. Here, we t
Externí odkaz:
https://doaj.org/article/cb0e43327b1d4f1c8b7dc50edb1d5e97
Autor:
Aimée Parker, Steve A. James, Catherine Purse, Arlaine Brion, Andrew Goldson, Andrea Telatin, David Baker, Simon R. Carding
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Age-associated changes in the structure of the intestinal microbiome and in its interaction with the brain via the gut-brain axis are increasingly being implicated in neurological and neurodegenerative diseases. Intestinal microbial dysbiosis and tra
Externí odkaz:
https://doaj.org/article/4d9aca07cb524a83a849da60e79ded4a
Publikováno v:
Gut Microbes, Vol 11, Iss 2, Pp 135-157 (2020)
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with the host. When intestinal homeostasis is perturbed, the function o
Externí odkaz:
https://doaj.org/article/d21307b03d76470fa9810437780da94f
Autor:
Louis Gall, Carrie Duckworth, Ferran Jardi, Lieve Lammens, Aimée Parker, Ambra Bianco, Holly Kimko, D. Mark Pritchard, Carmen Pin
We have built a multi-scale agent-based model (ABM) that reproduces the self-organizing behaviour reported for the intestinal crypt. We demonstrate that a stable spatial organization emerges from the dynamic interaction of multiple signalling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7723905fe6385cda270248e71fa1440
https://doi.org/10.1101/2022.12.18.520934
https://doi.org/10.1101/2022.12.18.520934
Autor:
Oliver J Maclaren, Aimée Parker, Carmen Pin, Simon R Carding, Alastair J M Watson, Alexander G Fletcher, Helen M Byrne, Philip K Maini
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 7, p e1005688 (2017)
Our work addresses two key challenges, one biological and one methodological. First, we aim to understand how proliferation and cell migration rates in the intestinal epithelium are related under healthy, damaged (Ara-C treated) and recovering condit
Externí odkaz:
https://doaj.org/article/c51090bb4d624b438d20bf4f061ad52c
Autor:
Emad Shehata, Aimée Parker, Toru Suzuki, Jonathan. R. Swann, Jotham Suez, Paul. A. Kroon, Priscilla Day‐Walsh
New Findings: What is the topic of this review? The role of the gut microbiome in physiology and how it can be targeted as an effective strategy against two of the most important global medical challenges of our time, namely, metabolic diseases and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5f68ce6af6955cd6b5160a192c575f
https://eprints.soton.ac.uk/455099/
https://eprints.soton.ac.uk/455099/
Autor:
Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery, Simon R. Carding
Publikováno v:
Microbiome. 10(1)
Background Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias. Here, we tested the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e1e96dce9ccf74148b4abb1ae1b21d
https://pubmed.ncbi.nlm.nih.gov/35501923
https://pubmed.ncbi.nlm.nih.gov/35501923
Autor:
Jan Salomonsen, John A Chattaway, Andrew C Y Chan, Aimée Parker, Samuel Huguet, Denise A Marston, Sally L Rogers, Zhiguang Wu, Adrian L Smith, Karen Staines, Colin Butter, Patricia Riegert, Olli Vainio, Line Nielsen, Bernd Kaspers, Darren K Griffin, Fengtang Yang, Rima Zoorob, Francois Guillemot, Charles Auffray, Stephan Beck, Karsten Skjødt, Jim Kaufman
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004417 (2014)
Many genes important in immunity are found as multigene families. The butyrophilin genes are members of the B7 family, playing diverse roles in co-regulation and perhaps in antigen presentation. In humans, a fixed number of butyrophilin genes are fou
Externí odkaz:
https://doaj.org/article/3bfc5bb7c6274a4188c491bf17d47bc0
Autor:
Oliver J, Maclaren, Aimée, Parker, Carmen, Pin, Simon R, Carding, Alastair J M, Watson, Alexander G, Fletcher, Helen M, Byrne, Philip K, Maini
Publikováno v:
PLoS Computational Biology
Our work addresses two key challenges, one biological and one methodological. First, we aim to understand how proliferation and cell migration rates in the intestinal epithelium are related under healthy, damaged (Ara-C treated) and recovering condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::829d03fde21922d7ee86b8b8e586af4b
https://pubmed.ncbi.nlm.nih.gov/28753601
https://pubmed.ncbi.nlm.nih.gov/28753601