Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ailing Tong"'
Autor:
Ailing Tong, John T Petroff II, Fong-Fu Hsu, Philipp AM Schmidpeter, Crina M Nimigean, Liam Sharp, Grace Brannigan, Wayland WL Cheng
Publikováno v:
eLife, Vol 8 (2019)
Pentameric ligand-gated ion channels (pLGICs) are essential determinants of synaptic transmission, and are modulated by specific lipids including anionic phospholipids. The exact modulatory effect of anionic phospholipids in pLGICs and the mechanism
Externí odkaz:
https://doaj.org/article/7d8ff2a346f24e4283e555d674e30404
Autor:
Gayathri K. Natarajan, Jyotsna Mishra, Qunli Cheng, Ailing Tong, Amadou K. Camara, Wai-Meng Kwok
Publikováno v:
Biophysical Journal. 122:399a-400a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fc10a1c6dfea4c9e6bdab9784c9a7fb
https://doi.org/10.1016/j.bpj.2022.11.2180
https://doi.org/10.1016/j.bpj.2022.11.2180
Autor:
Carl Frieden, Farha Khan, Gregory T. DeKoster, John T. Petroff, Lawrence J. Chen, Jeff Abramson, Wayland W.L. Cheng, Ailing Tong
Publikováno v:
Anal Chem
Native mass spectrometry paired with ion mobility (IM-MS) provides the capacity to monitor the structure of protein complexes and simultaneously assess small molecule binding to the protein. Native IM-MS typically utilizes positive mode electrospray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492637df9035708ba456726166914924
https://doi.org/10.1021/acs.analchem.0c00454
https://doi.org/10.1021/acs.analchem.0c00454
Autor:
Fong-Fu Hsu, Grace Brannigan, Ailing Tong, Wayland W.L. Cheng, Liam Sharp, Crina M. Nimigean, Philipp A. M. Schmidpeter, John T. Petroff
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Pentameric ligand-gated ion channels (pLGICs) are essential determinants of synaptic transmission, and are modulated by specific lipids including anionic phospholipids. The exact modulatory effect of anionic phospholipids in pLGICs and the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a982af5996e9e7ccf3136dcc7f7c5686
https://elifesciences.org/articles/50766
https://elifesciences.org/articles/50766
Autor:
Liam Sharp, John T. Petroff, Grace Brannigan, Philipp A. M. Schmidpeter, Wayland Wl Cheng, Ailing Tong, Fong-Fu Hsu, Crina M. Nimigean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0a7f26e57edc2d49eeff49e87ddf7b
https://doi.org/10.7554/elife.50766.024
https://doi.org/10.7554/elife.50766.024
Autor:
Philipp A. M. Schmidpeter, Fong-Fu Hsu, Ailing Tong, Liam Sharp, Crina M. Nimigean, John T. Petroff, Grace Brannigan, Wayland W.L. Cheng
Pentameric ligand-gated ion channels (pLGICs) are essential determinants of synaptic transmission, and are modulated by specific lipids including anionic phospholipids. The exact modulatory effect of anionic phospholipids in pLGICs and the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3238b1d606034e13f9803ac0cd76b9ee
https://doi.org/10.1101/722512
https://doi.org/10.1101/722512
Publikováno v:
Journal of Biological Chemistry. 284:2854-2860
Potassium channels are tetrameric proteins that mediate K(+)-selective transmembrane diffusion. For KcsA, tetramer stability depends on interactions between permeant ions and the channel pore. We have examined the role of pore blockers on the tetrame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e24cc0b183afb9f311627781674c052
https://doi.org/10.1074/jbc.m807474200
https://doi.org/10.1074/jbc.m807474200
Autor:
Jonathan V. Rocheleau, Colin G. Nichols, Maria S. Remedi, Joseph C. Koster, Ailing Tong, David W. Piston, Michael L. McDaniel, Brian Patton
Publikováno v:
Diabetologia. 49:2368-2378
ATP-sensitive K(+) (K(ATP)) channels couple glucose metabolism to insulin secretion in pancreatic beta cells. In humans, loss-of-function mutations of beta cell K(ATP) subunits (SUR1, encoded by the gene ABCC8, or Kir6.2, encoded by the gene KCNJ11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b394840d51f083b0f4c36b1c8a14dad7
https://doi.org/10.1007/s00125-006-0367-4
https://doi.org/10.1007/s00125-006-0367-4
Publikováno v:
Biophysical Journal. 96(3)
Potassium channels are tetrameric proteins that mediate K+ selective transmembrane diffusion. For the prototypic potassium channel KcsA, interactions between ions and the channel pore can modulate the stability of the tetrameric structure of KcsA, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817801d8e5f448515909dee0ff621414
Autor:
Alexis Scott, Joseph C. Koster, Colin G. Nichols, F. Thomas Wunderlich, Eva Rother, André Kleinridders, Maria S. Remedi, Harley T. Kurata, Jens C. Brüning, Ailing Tong
Publikováno v:
Cell metabolism. 9(2)
ATP-insensitive K(ATP) channel mutations cause neonatal diabetes mellitus (NDM). To explore the mechanistic etiology, we generated transgenic mice carrying an ATP-insensitive mutant K(ATP) channel subunit. Constitutive expression in pancreatic beta c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c485ac8314f208fcf6ed2db874fdb018
https://pubmed.ncbi.nlm.nih.gov/19187772
https://pubmed.ncbi.nlm.nih.gov/19187772