Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ailing Du"'
Autor:
Hao Liu, Yue Zhang, Mitchell Yip, Lingzhi Ren, Jialing Liang, Xiupeng Chen, Nan Liu, Ailing Du, Jiaming Wang, Hao Chang, Hyejin Oh, Chen Zhou, Ruxiao Xing, Mengyao Xu, Peiyi Guo, Dominic Gessler, Jun Xie, Phillip W.L. Tai, Guangping Gao, Dan Wang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101230- (2024)
Recombinant adeno-associated virus (rAAV)-based gene therapy is entering clinical and commercial stages at an unprecedented pace. Triple transfection of HEK293 cells is currently the most widely used platform for rAAV manufacturing. Here, we develop
Externí odkaz:
https://doaj.org/article/60f1fe4d77694132aa0fbf4e90bcd7e3
Autor:
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip WL Tai, Guangping Gao, Jun Xie
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 945-965 (2024)
Abstract Physiological regulation of transgene expression is a major challenge in gene therapy. Onasemnogene abeparvovec (Zolgensma®) is an approved adeno-associated virus (AAV) vector gene therapy for infants with spinal muscular atrophy (SMA), how
Externí odkaz:
https://doaj.org/article/4e7a21bfc0d24ec095ce22f8d8fa7575
Autor:
Hao Chang, Ailing Du, Jun Jiang, Lingzhi Ren, Nan Liu, Xuntao Zhou, Jialing Liang, Guangping Gao, Dan Wang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101129- (2023)
Gene therapy using recombinant adeno-associated virus (rAAV) relies on safe, efficient, and precise in vivo gene delivery that is largely dependent on the AAV capsid. The proteinaceous capsid is highly amenable to engineering using a variety of appro
Externí odkaz:
https://doaj.org/article/ea71cd7d510646e991a46aa0bf3a4f1a
Autor:
Qiuhong Jiao, Baoting Liu, Xiufeng Xu, Tao Huang, Bufan Cao, Lide Wang, Qingguo Wang, Ailing Du, Jingtian Li, Baolong Zhou, Tao Wang
Publikováno v:
RSC Advances. 13:5444-5456
Alleviation of doxorubicin-induced cardiotoxicity by a biodegradable porous organic polymer drug delivery system via passive targeted release.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ecc559080eb3f7f24f66d29c00af7fd
https://doi.org/10.1039/d2ra07410a
https://doi.org/10.1039/d2ra07410a
Autor:
Mandana Arbab, Zaneta Matuszek, Kaitlyn M. Kray, Ailing Du, Gregory A. Newby, Anton J. Blatnik, Aditya Raguram, Michelle F. Richter, Kevin T. Zhao, Jonathan M. Levy, Max W. Shen, W. David Arnold, Dan Wang, Jun Xie, Guangping Gao, Arthur H. M. Burghes, David R. Liu
Publikováno v:
Science. 380
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality, arises from survival motor neuron (SMN) protein insufficiency resulting from SMN1 loss. Approved therapies circumvent endogenous SMN regulation and require repeated dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da790fc009f5f996838b159db859f45f
https://doi.org/10.1126/science.adg6518
https://doi.org/10.1126/science.adg6518
Autor:
Qin Shen, Xiaohu Zhang, Hanhan Chen, Ailing Du, Xiao Han, Xiaojing Wu, Chunjie Zhao, Bin Liu, Qing-Ran Bai, Zhaoying Ding
Publikováno v:
Cerebral Cortex. 29:4968-4981
During early development, signaling centers, such as the cortical hem and the preoptic area (POA), are critical for telencephalic patterning. However, the mechanisms underlying the maintenance of signal centers are poorly understood. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fbcc0c66f24922d666f78f0d643831
https://doi.org/10.1093/cercor/bhz037
https://doi.org/10.1093/cercor/bhz037
Autor:
Bingna Cai, Xiangxi Yi, Zhou Wang, Xiangtan Zhao, Ailing Duan, Hua Chen, Peng Wan, Deke Chen, Jingtong Huang, Jianyu Pan
Publikováno v:
Journal of Functional Foods, Vol 110, Iss , Pp 105846- (2023)
This study aims to investigate the anti-fatigue effect and mechanism of Syngnathus schlegeli peptides (SAP) on exercise-fatigued mice. Compared to the control group, SAP significantly reduced the accumulation of metabolites LA, BUN and MDA, increased
Externí odkaz:
https://doaj.org/article/56034d0bead441e3b5119ffca94c43d8
Publikováno v:
Ceramics International. 40:8801-8808
The efficiency of silicon removal technology by acid leaching and flocculation during zirconium oxychloride octahydrate (ZrOCl2 center dot 8 H2O) production has been improved. The optimum conditions of acid leaching were found to be as follows: trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f3b318cc0ea16af4066f82b323484d
https://doi.org/10.1016/j.ceramint.2014.01.102
https://doi.org/10.1016/j.ceramint.2014.01.102
Publikováno v:
Ceramics International. 40:1431-1438
The water leaching and transition process in manufacturing zirconium oxychloride octahydrate was examined. Results from X-ray diffraction (XRD) and Fourier-transform infrared (FT-IR) spectra showed that most of the soluble sodium silicate was dissolv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0608e6ca1e89dbec87e1b68257271a65
https://doi.org/10.1016/j.ceramint.2013.07.026
https://doi.org/10.1016/j.ceramint.2013.07.026
Publikováno v:
Kuangchan zonghe liyong, Vol 43, Iss 6, Pp 104-109 (2022)
With the intensification of mining activities, the problem of soil pollution in mining area becomes more and more serious. Nowadays, the main methods include physical remediation, chemical remediation, bio-remediation and so on. Among them, chemical
Externí odkaz:
https://doaj.org/article/891794c5cbed41a18f7e244a79baa89c