Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aileen Weiwei Li"'
Autor:
Hua Wang, Alexander J. Najibi, Miguel C. Sobral, Bo Ri Seo, Jun Yong Lee, David Wu, Aileen Weiwei Li, Catia S. Verbeke, David J. Mooney
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The immunosuppressive tumour microenvironment impairs immunotherapy in poorly immunogenic cancer. Here, the authors load an alginate gel with GM-CSF, CpG oligonucleotides and doxorubicin-iRGD to promote immunogenic death of tumour cells and improve i
Externí odkaz:
https://doaj.org/article/2af10e759cc3482da0ca26d55a1844d7
Autor:
Jun Yong Lee, David J. Mooney, Bo Ri Seo, David M. Wu, Catia S. Verbeke, Miguel C. Sobral, Hua Wang, Aileen Weiwei Li, Alexander J. Najibi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Poorly immunogenic tumors, including triple negative breast cancers (TNBCs), remain resistant to current immunotherapies, due in part to the difficulty of reprogramming the highly immunosuppressive tumor microenvironment (TME). Here we show that peri
Autor:
Christina M. Tringides, Hua Wang, David K.Y. Zhang, Adam N.R. Cartwright, Maxence O. Dellacherie, David J. Mooney, Aileen Weiwei Li, Sandeep T. Koshy, Kai W. Wucherpfennig, Miguel C. Sobral
Publikováno v:
Nat Mater
Targeted immunomodulation of dendritic cells (DCs) in vivo will enable manipulation of T-cell priming and amplification of anticancer immune responses, but a general strategy has been lacking. Here we show that DCs concentrated by a biomaterial can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb7884234c8f2e40f7ad873c6b00f3f
https://europepmc.org/articles/PMC7748064/
https://europepmc.org/articles/PMC7748064/
Autor:
Aileen Weiwei Li, Young Jin Choi, Soumya Badrinath, Kai W. Wucherpfennig, Maxence O. Dellacherie, Jaeyun Kim, Alexander G. Stafford, James C. Weaver, Amanda R. Graveline, Ting-Yu Shih, David J. Mooney, Miguel C. Sobral, Omar Abdel-Rahman Ali
Publikováno v:
Nature Materials. 17:528-534
Existing strategies to enhance peptide immunogenicity for cancer vaccination generally require direct peptide alteration, which, beyond practical issues, may impact peptide presentation and result in vaccine variability. Here, we report a simple adso