Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Aileen Wee"'
The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD
Autor:
Zun Siong Low, Damien Chua, Hong Sheng Cheng, Rachel Tee, Wei Ren Tan, Christopher Ball, Norliza Binte Esmail Sahib, Ser Sue Ng, Jing Qu, Yingzi Liu, Haiyu Hong, Chaonong Cai, Nandini Chilagondanahalli Lakshmi Rao, Aileen Wee, Mark Dhinesh Muthiah, Zoë Bichler, Barbara Mickelson, Mei Suen Kong, Vanessa Shiyun Tay, Zhuang Yan, Jiapeng Chen, Aik Seng Ng, Yun Sheng Yip, Marcus Ivan Gerard Vos, Nicole Ashley Tan, Dao Liang Lim, Debbie Xiu En Lim, Manesh Chittezhath, Jadegoud Yaligar, Sanjay Kumar Verma, Harish Poptani, Xue Li Guan, Sambasivam Sendhil Velan, Yusuf Ali, Liang Li, Nguan Soon Tan, Walter Wahli
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) represents an impending global health challenge. Current management strategies often face setbacks, emphasizing the need for preclinical models that faithfully mimic the huma
Externí odkaz:
https://doaj.org/article/516eada6ebe94695a2023966be28ab43
Autor:
Feng Liu, Yameng Sun, Dean Tai, Yayun Ren, Elaine L. K. Chng, Aileen Wee, Pierre Bedossa, Rui Huang, Jian Wang, Lai Wei, Hong You, Huiying Rao
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1837 (2024)
This study aimed to understand the dynamic changes in fibrosis and its relationship with the evaluation of post-treatment viral hepatitis using qFibrosis. A total of 158 paired pre- and post-treatment liver samples from patients with chronic hepatiti
Externí odkaz:
https://doaj.org/article/d7c4cad561b24399ab43bd36607d3c23
Autor:
Laurent Gole, Feng Liu, Kok Haur Ong, Longjie Li, Hao Han, David Young, Gabriel Pik Liang Marini, Aileen Wee, Jingmin Zhao, Huiying Rao, Weimiao Yu, Lai Wei
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The novel targeted therapeutics for hepatitis C virus (HCV) in last decade solved most of the clinical needs for this disease. However, despite antiviral therapies resulting in sustained virologic response (SVR), a challenge remains where th
Externí odkaz:
https://doaj.org/article/1ad235e0a7b34bf6aa2bad6e5e2b0113
Autor:
Piyapharom Intarawichian, Sirada Sangpaibool, Piya Prajumwongs, Prakasit Sa-Ngiamwibool, Sakkarn Sangkhamanon, Waritta Kunprom, Malinee Thanee, Watcharin Loilome, Narong Khuntikeo, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Kulyada Eurboonyanun, Julaluck Promsorn, Supinda Koonmee, Aileen Wee, Chaiwat Aphivatanasiri
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Patients with distal cholangiocarcinoma (dCCA) generally have poor outcomes because of late presentation and diagnosis. Therefore, prognostic factors for predicting outcomes are essential to improve therapeutic strategies and quality of life. Tumor-i
Externí odkaz:
https://doaj.org/article/91fd694fbf424e87999b275bb5c979c3
Autor:
Chaiwat Aphivatanasiri, Prakasit Sa-Ngiamwibool, Sakkarn Sangkhamanon, Piyapharom Intarawichian, Waritta Kunprom, Malinee Thanee, Piya Prajumwongs, Narong Khuntikeo, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Kulyada Eurboonyanun, Julaluck Promsorn, Watcharin Loilome, Aileen Wee, Supinda Koonmee
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
AimThis study aims to improve the classification performance of the eighth American Joint Committee on Cancer (AJCC) staging system for perihilar cholangiocarcinoma (pCCA) by proposing the Khon Kaen University (KKU) staging system developed in cholan
Externí odkaz:
https://doaj.org/article/7ed45ac1a01f45a7b87310e088facf7d
Autor:
Ruiyuan Yang, Kexin Li, Cailun Zou, Aileen Wee, Jimin Liu, Liwei Liu, Min Li, Ting Wu, Yu Wang, Zikun Ma, Yan Wang, Jingyi Liu, Ang Huang, Ying Sun, Binxia Chang, Qingsheng Liang, Jidong Jia, Zhengsheng Zou, Xinyan Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Aims: To develop, optimize, and validate a novel model using alanine aminotransferase (ALT) and total bilirubin (TB) dynamic evolution patterns in predicting acute liver failure (ALF) in drug-induced liver injury (DILI) patients.Methods: The demograp
Externí odkaz:
https://doaj.org/article/f51a320e308b41b4ace7ddfd5603edf8
Autor:
Feng Liu, Lai Wei, Wei Qiang Leow, Shu-Hong Liu, Ya-Yun Ren, Xiao-Xiao Wang, Xiao-He Li, Hui-Ying Rao, Rui Huang, Nan Wu, Aileen Wee, Jing-Min Zhao
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundThe evolution of pediatric non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH) is associated with unique histological features. Pathological evaluation of liver specimen is often hindered by observer variabilit
Externí odkaz:
https://doaj.org/article/661f4af5528a419387445a8a0f0e4eb9
Autor:
Gwyneth Soon, Aileen Wee
Publikováno v:
Clinical and Molecular Hepatology, Vol 27, Iss 1, Pp 44-57 (2021)
Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) is a major cause of liver fibrosis and cirrhosis. Accurate assessment of liver fibrosis is important for predicting disease outcomes and assessing therapeutic response in clin
Externí odkaz:
https://doaj.org/article/6f733b7f15df425f94571a909097ac4a
Autor:
Daniel Q. Huang, Mark D. Muthiah, Lei Zhou, Halisah Jumat, Wan Xin Tan, Guan Huei Lee, Seng Gee Lim, Alfred Kow, Glenn Bonney, Iyer Shridhar, Yi Ting Lim, Aileen Wee, Yin Huei Pang, Gwyneth Soon, Pierce Chow, Yock Young Dan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1313-1325 (2021)
Background & Aims: Hepatocellular carcinoma (HCC) arises in a cirrhotic, pro-angiogenic microenvironment. Inhibiting angiogenesis is a key mode of action of multikinase inhibitors and current non-cirrhotic models are unable to predict treatment respo
Externí odkaz:
https://doaj.org/article/7ba8b6da13ae443ebf3680b9ffa1d1a7
Autor:
Gwyneth Shook Ting Soon, Aileen Wee
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 64, Iss 5, Pp 104-111 (2021)
Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) is a major cause of liver fibrosis/cirrhosis and liver-related mortality. Despite emergence of noninvasive tests, liver biopsy remains the mainstay for the diagnosis and asses
Externí odkaz:
https://doaj.org/article/86e35ff04b0b4afda29654ecb13f3e75