Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Aileen Höhne"'
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Abstract 2835: Fibroblast activation protein (FAP)-targeted radiotherapy increases tumor CD8+ T cell infiltration and enhances response to PD-1 immune checkpoint blockade
Autor: Dirk Zboralski, Aileen Höhne, Esben Christensen, Matthias Paschke, Liliane Robillard, Andrew D. Simmons, Frank Osterkamp, Thomas C. Harding, Minh Nguyen
Publikováno v: Cancer Research. 83:2835-2835
Background: FAP is a membrane-bound protease under investigation as a pan-cancer target, given its high expression in tumors but limited expression in normal tissues. FAP-2286 is a FAP-targeted radiopharmaceutical in clinical development for multiple
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c602490b0ff34a3a132453716847659c
https://doi.org/10.1158/1538-7445.am2023-2835
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2
Proof of Therapeutic Efficacy of a 177Lu-Labeled Neurotensin Receptor 1 Antagonist in a Colon Carcinoma Xenograft Model
Autor: Martin Rohracker, Christiane Smerling, Holger Amthauer, Aileen Höhne, Jürgen Goldschmidt, Anette Pethe, Mercedes Noriega, Ulrich Reineke, Marvin Stiebler, Jörg Schulz, Frank Osterkamp, Mathias Lukas, Franziska Stöber
Publikováno v: Journal of Nuclear Medicine. 58:936-941
Increased expression of neurotensin receptor 1 (NTR1) has been shown in a large number of tumor entities such as pancreatic or colon carcinoma. Hence, this receptor is a promising target for diagnostic imaging and radioligand therapy. Using the favor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c490a9fee3ccf56b901a6cb975baadc
https://doi.org/10.2967/jnumed.116.185140
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3
Proof of Therapeutic Efficacy of a
Autor: Jörg, Schulz, Martin, Rohracker, Marvin, Stiebler, Jürgen, Goldschmidt, Franziska, Stöber, Mercedes, Noriega, Anette, Pethe, Mathias, Lukas, Frank, Osterkamp, Ulrich, Reineke, Aileen, Höhne, Christiane, Smerling, Holger, Amthauer
Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(6)
Increased expression of neurotensin receptor 1 (NTR1) has been shown in a large number of tumor entities such as pancreatic or colon carcinoma. Hence, this receptor is a promising target for diagnostic imaging and radioligand therapy. Using the favor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e238eca8b92e8fdc525bf56a093188d8
https://pubmed.ncbi.nlm.nih.gov/28254866
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6
Organofluorosilanes as model compounds for 18F-labeled silicon-based PET tracers and their hydrolytic stability: experimental data and theoretical calculations (PET = positron emission tomography)
Autor: Simon M. Ametamey, Linjing Mu, Ulrike Voigtmann, Ulrich Klar, Markus Reiher, P. August Schubiger, Aileen Höhne, Keith Graham, Lian Yu
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 15(15)
Silicon chemistry has only recently been discovered by radiochemists as a straightforward tool for the introduction of 18 F into biomolecules for positron emission tomography (PET) imaging. 18 F-labeled PET tracers must be stable towards defluorinati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2b3d1970c4f7fd119542003e800e74
https://pubmed.ncbi.nlm.nih.gov/19267382
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7
Synthesis, 18F-labeling, and in vitro and in vivo studies of bombesin peptides modified with silicon-based building blocks
Autor: P. August Schubiger, Timo Stellfeld, Linjing Mu, Ulrike Voigtmann, Dietmar Berndorff, Simon M. Ametamey, Matthias Friebe, John E. Cyr, Ulrich Klar, Michael Honer, Sandra Borkowski, Aileen Höhne, Keith Graham, Ludger Dinkelborg, Ananth Srinivasan
Publikováno v: Bioconjugate chemistry. 19(9)
The gastrin-releasing peptide receptor (GRPr) is overexpressed on various human tumors. The goal of our study was the synthesis of new 18F-labeled bombesin analogues for the PET imaging of GRPr expression in prostate tumor using a silicon-based one-s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28460236ade71b19001ef8a8994c196b
https://pubmed.ncbi.nlm.nih.gov/18754574
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