The Importance of 1,5‐Oxygen⋅⋅⋅Chalcogen Interactions in Enantioselective Isochalcogenourea Catalysis

Autor: Andrew Woods, Claire M. Young, Andrew D. Smith, Scott L. Cockroft, Alexandra M. Z. Slawin, Aileen B. Frost, Calum McLaughlin, Patrick H. Willoughby, Terry K. Smith, Dominic J. Pascoe, Alix de la Houpliere, Rylie K. Morris, Kenneth Ling, Alex Elmi

Publikováno v: Young, C, Elmi, A, Pascoe, D, Morris, R, McLaughlin, C, Woods, A, Frost, A, de la Houpliere, A, Ling, K, Smith, T K, Slawin, A M Z, Willoughby, P, Cockroft, S & Smith, A 2019, ' The importance of 1,5-oxygen-chalcogen interactions in enantioselective isochalcogenourea catalysis ', Angewandte Chemie International Edition . https://doi.org/10.1002/anie.201914421

Syngenta (Case Award to DJP) and a Philip Leverhulme Prize for funding (SLC, AE). RKM and PHW are grateful to the American Chemical Society Petroleum Research Fund and National Science Foundation (NSF-MRI: CHE-1429616). The importance of 1,5-O···c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe3991a8b54e85ab2e715c519369e95
https://doi.org/10.1002/ange.201914421

Direct Organocatalytic Enantioselective Functionalization of SiOxSurfaces

Autor: John David Parkin, Ross Chisholm, Aileen B. Frost, Richard G. Bailey, Georg Hähner, Andrew D. Smith

Publikováno v: Angewandte Chemie. 130:9521-9525

We thank the Engineering and Physical Sciences Research Council (GH, ADS and JDP acknowledge EP/K000411/1 and EP/L017008/1, and ADS and ABF acknowledge EP/J018139/1) and the Leverhulme Trust (GH and RGB acknowledge RPG2015-109). This work was support

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb94a98d085bff8486898957e7c1ffe
https://doi.org/10.1002/ange.201804814

Trading N and O. Part 3: Synthesis of 1,2,3,4-tetrahydroisoquinolines from α-hydroxy-β-amino esters

Autor: Matthew S. Kennedy, Paul M. Roberts, Stephen G. Davies, Aileen B. Frost, James E. Thomson, Ai M. Fletcher

Publikováno v: Tetrahedron. 72:2139-2163

All rights reserved.A range of enantiopure 1,2,3,4-tetrahydroisoquinolines have been prepared directly from α-hydroxy-β-amino esters. Activation of the α-hydroxy group upon treatment with Tf2O and 2,6-di-tert-butyl-4-methylpyridine promotes azirid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c962bbfd6812c3d4578c1b2bf6a385fd
https://doi.org/10.1016/j.tet.2016.03.008

Direct Organocatalytic Enantioselective Functionalization of SiO

Autor: John D, Parkin, Ross, Chisholm, Aileen B, Frost, Richard G, Bailey, Andrew D, Smith, Georg, Hähner

Publikováno v: Angewandte Chemie (International ed. in English). 57(30)

Traditional methods to prepare chiral surfaces involve either the adsorption of a chiral molecule onto an achiral surface, or adsorption of a species that forms a chiral template creating lattices with long range order. To date only limited alternati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69d31fb51f3367436e63ab4301de9aa6
https://pubmed.ncbi.nlm.nih.gov/29870577

Trading N and O: asymmetric syntheses of β-hydroxy-α-amino acids via α-hydroxy-β-amino esters

Autor: Aileen B. Frost, Paul M. Roberts, Ai M. Fletcher, James A. Lee, Stephen G. Davies, James E. Thomson

Publikováno v: Tetrahedron. 69:8885-8898

Both diastereoisomers of 2-amino-3-hydroxybutanoic acid and 2-amino-3-hydroxy-3-phenylpropanoic acid have been prepared from enantiopure α-hydroxy-β-amino esters via the intermediacy of the corresponding cis- and trans-aziridines. Aminohydroxylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3adc6abd544c3e96a0f6adbfaf6c2c42
https://doi.org/10.1016/j.tet.2013.08.007